RESUMEN
Neuroblastomas are among the most important tumors of extra cranial origin in pediatric patients. They arise from emyonal cells involved in the development of the sympathetic nervous system, whose differentiation has been arrested [1, 2]. This article describes an atypical presentation of ganglioneuroblastoma in a 52 year old male patient. X– Ray left hand in AP and Lateral views showed it as a soft tissue swelling. Excision was done under digital block, and excised specimen was sent to department of pathology for histo pathological examination. HPE showed it as gangioneuroblastoma and pathologists advised to get immunohistochemistry for cathepsin D to be done.
RESUMEN
Schwannian stroma poor calcified bilateral neuroblastoma of adrenal gland in 14 year old male patient is an exceptionally uncommon, malignant tumor that is derived from the primitive neural crest cells of the adrenal medulla. Neuroblastoma is the fourth most common malignancy of childhood up to five years of age, and very occasionally seen after that. It rarely occurs in the adrenal gland after ten years of age and bilaterally. The diagnosis was established based on clinical, radiological, histopathological and immunohistochemical features. At present, the patient is on chemotherapy and radiotherapy but the recent MRI is showing bilateral pubic bone and femur metastasis. Conclusion: Schwannian stroma poor calcified bilateral neuroblastoma of adrenal gland is a rare tumor at the age of 14 years which needs precise histopathological assessment and confirmation by Immunohistochemistry.