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Objective To observe the efficacy of Shenling Baizhu powder combined with Erchentang in treatment of senile pneumonia, and its influence on serum procalcitonin. Methods With randomized controlled trial, 100 patients were randomly divided into two groups. The control group (49 cases) was treated by routine western medicine, and the treatment group (51 cases) was treated by Shenling Baizhu powder combined with Erchentang additionally. The treatment course was 1 week, and the therapeutic effect was observed after two courses. The improvement time of clinical symptoms and signs, and the change of serum procalcitonin were detected. Results Clinical efficacy of the two groups had no significant difference (P>0.05). The improvement time of signs and symptoms in treatment group was better than that in control group (P<0.05). The serum procalcitonin improved in treatment group was better than that in control group (P<0.05). Conclusion Shenling Baizhu powder combined with Erchentang has obvious anti-infection effect, and can improve symptoms and signs of senile pneumonia rapidly.
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Acinetobacter baumannii.Sixty(20.6%) strains of Gram-positive bacteria were isolated.Staphylococcus aureus was the most predominat pathogen(13.0%),meticillin-resistant S.aureus(MRSA)(72.8%).Twenty-nine(10.0%) strains of fungi were isolated,Candida albicans was the most predominant(7.56%).The result of drug sensitive test showed that there were high rates of multiple drug resistance in most bacteria strains,but there were high different drug resistance rates to different antibiotics.Ampicillin had the highest resistance rate nearly 100%.In contrast,the imipenem resistance had the lower resistance rate from 0-14.3%.Lactamases(ESBLs) in K.pneumoniae and E.coli were 56.5% and 41.2%. CONCLUSIONS Gram-negitive bacteria are major pathogens in pneumonia of aged.There are high rates of multiple drug resistance in bacteria strains.The clinic should reasonably choose the antibiotics according to the test results of the pathogens sensitivity to drugs.
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Objective To observe the clinical effect of Herba Houttuyniae Injection in treating senile pneumonia and to explore its possible mechanism. Methods Sixty-five patients were randomly divided into two groups. The control group was treated with conventional western therapy (CWT), while the treatment group was treated with CWT plus Herba Houttuyniae Injection. The changes of serum cytokines, IL-2 and TNF-?, before and after treatment were observed. Results the total effective rate of treatment group is 94.3%, while that of the control group is 83.3%. The difference of the total effective rate between the two groups was significant(P