Acupuncture at pharyngeal acupoints for true bulbar paralysis after cerebral infarction: a randomized controlled trial / 中国针灸

OBJECTIVE@#To compare the clinical effect of acupuncture at the affected side and both sides of the pharyngeal acupoints for true bulbar paralysis after cerebral infarction.@*METHODS@#A total of 66 patients with true bulbar paralysis after cerebral infarction were randomly divided into an unilateral group and a bilateral group, 33 cases in each group, 1 case dropped off in each group at last. On the basis of conventional drugs and electro-nape-acupuncture treatment, the patients in the unilateral group were treated with acupuncture at the affected side's , and (Extra), while patients in the bilateral group were treated with acupuncture at the both sides' , and The treatment was performed once a day, 6 days a week, and the clinical effect was assessed after 21-day therapy. The swallowing and vocalization of the two groups were evaluated by dysphagia grading scale, Kubota water swallowing test and GRBAS grading scale before and after treatment.@*RESULTS@#After 21 days of treatment, the scores of the dysphagia grading scale in the two groups were both improved (<0.01), and the unilateral group was superior to the bilateral group (<0.01). The GRBAS grading scale and Kubota water swallowing test grading after treatment were improved in both groups (<0.01), and the unilateral group was superior to the bilateral group (<0.05, <0.01).@*CONCLUSION@#Acupuncture at the pharyngeal acupoints of the affected side achieves much better therapeutic effect on true bulbar paralysis as compared with the acupoints of the bilateral sides.

Should Japanese physicians' professionalism be based on "bushido" , a business philosophy, or benevolence? / 医学教育

<p>　Professionalism was featured in this scientific journal the other day, and a paper on whether or not bushido, or Japanese chivalry, could serve as a model of professionalism required for Japanese physicians was published in it. Following this, the issue was also discussed in a paper written by Iwata. From my point of view, Japanese physicians should learn professionalism from Confucianism including the teachings of Confucius, the basis of Japanese chivalry, rather than bushido itself, as recommended in a paper written by Nishigori.</p><p></p><p>　On the other hand, Sanpo-yoshi (benefits for all three sides), or a business philosophy, introduced by Nomura in his paper, is family profit-oriented and irrelevant to the above-mentioned "not-for-profit" professionalism. It has been said that "medicine is benevolent art" , and the basis of education on professionalism for Japanese physicians will be developed by learning about "benevolence" from the Analects of Confucius.</p>

Study on the Extraction Technology of Compound Qima Capsules / 中国药房

OBJECTIVE:To optimize the extraction technology of Compound qima capsules. METHODS:With the blood pres-sure lowering of rats as index,pharmacological efficacy test was used to screen the preparation technology(A was whole herb de-coction;B was Gastrodia elata fine powder mixed with other decocted medical materials). The extraction technology was opti-mized by single factor and orthogonal test using the contents of astragaloside and isoflavone grape glycosides and the quality of sol-id as indexes,with added water,decoction time,decoction times as factors;and the verification test was carried out. RESULTS:Pharmacological efficacy test showed that antihypertensive effect of sample by technology B was superior. The optimal extraction condition of other medical materials of technology B was as follows as 12-fold water per time,decocting for 1.5 h,for 3 times. In verification test,average extraction rates of astragaloside and isoflavone grape glycosides were 64.02% and 51.97%,and average value of the quality of solid was 5.69 g(RSD≤1.92%,n=3). CONCLUSIONS:The optimized extraction technology is stable and feasible.

Efficacy of Bevacizumab monotherapy on radiation-induced brian necrosis / 中华放射医学与防护杂志

Objective To explore the effects and safety of bevacizumab monotherapy on radiationinduced brain necrosis in patients with head and neck cancer.Methods Twenty-three patients with radiation-induced brain necrosis received intravenous injection of bevacizumab 5 mg/kg every 2 weeks for 4 cycles.Before and 2 weeks after the treatment LENT/SOMA scoring system,Montreal Cognitive Assessment (MoCA),and MRI were used to evaluate the scores of subjective and objective items,cognitive scores,and the extent of edema.Adverse effects were observed.Results Two patients suffered from grade 2 rhinorrhagia after the first dose and had to give up the therapy.Twenty-one patients received the full dose of bevacizumab and showed improvement in clinical signs and symptoms.The MoCA score after treatment was significantly higher than that before treatment (t =3.166,P ＜ 0.05).MRI T2-weighted image showed that the volume of brain edema was decreased by (53.9 ± 22.13)％ on average (Z =-5.645,P ＜0.05).One patient showed mild exacerbation of the extent of focus on MRI after the second cycle therapy but still showed significant improvement at the end of four cycles.Of the 21 cases that successfully finished the whole treatment,one suffered from grade 2 rash and one had mild intracranial hemorrhage,however,no grade 3 to 5 adverse reactions were observed.Conclusions Bevacizumab monotherapy may have a rapid and safe therapeutic effect on radiation necrosis.

Application of central region cervical lymph nodes dissection in papillary thyroid microcarcinoma with clinically node-negative sides of neck stage / 中国医师进修杂志

Objective To analyze the application value of central region cervical lymph nodes dissection in papillary thyroid microcarcinoma (PTMC) with clinically node-negative sides of neck stage.Methods Clinical data of 72 PTMC patients with clinically node-negative sides of neck stage were collected,and they were underwent total thyroidectomy,isthmic portion excision and contralateral lobus glandularis excision and neck dissection.A long term follow-up was made.Results Twenty-four patients were found central region cervical lymph nodes metastasis while other 48 patients were not found central region cervical lymph nodes metastasis.Followed up for 1.5-4.5 (3.4 ± 1.1) years,4 patients were found recurrent laryngeal nerve paralysis and recovered within 4 months.Four patients were found central region cervical lymph nodes metastasis after operation the 3rd years.Conclusions There is a tendency for PTMC patients with clinically node-negative sides of neck stage to occur central region cervical lymph nodes metastasis,it's necessary to perform prophylactic central region dissection.It can decrease the complications and improve the prognosis.

Choice of Initial Operation and Functional Outcome in Rotator Cuff Repair on Both Shoulder / 대한정형외과학회잡지

PURPOSE: We evaluated the influencing factors in selection of initial operation and outcomes after operative treatment of symptomatic rotator cuff tear including both sides. MATERIALS AND METHODS: From December 2000 to March 2011, 60 shoulders of 30 patients underwent arthroscopic rotator cuff repair by a single experienced shoulder surgeon in our clinic. We retrospectively compared outcome by operation order according to hand dominance, tear size and by operation timing, operation method, and tear size. Symptom period was 10 months until the first operation and 19 months until the second operation. Interval between first and second operation was nine months. RESULTS: In comparison by operation order according to hand dominance and tear size, the functional scores did not differ significantly between the initial repair and delayed repair group (p>0.05). In comparison in a total of 60 cases, the functional outcome according to the operation timing and method of operation was not significantly different (p>0.05). The smaller sized tear group showed significantly better functional outcome, compared to the larger sized tear group (p<0.05). CONCLUSION: In cases of both-side symptomatic rotator cuff tear, most operations were performed on the more symptomatic side and the dominant arm first. The functional outcome showed improvement, regardless of operation order according to hand dominance and tear size, and regardless of operation timing and operation method as well. Tear size was the only significant factor influencing functional outcome.

Comparison of medical imaging technique professionals' education and working system between Chinese mainland and Taiwan region / 中华医学教育探索杂志

There are great differences in the education and working system of certain professionals between Chinese mainland and Taiwan region due to the differeuces in the political system.In this essay,we try to compare the differences in the education level,objective and course offering of the medical imaging technique major and the differences in the professional qualification examination system and the working system between Chinese Mainland and Taiwan Region.We also probe into the possible fields for both sides to learn from each other and to provide references for cooperative school - running,professionals' interchange and working system of medical imaging technique majors of both sides.

Looking for future cooperation through both sides of the Taiwan Straits' exchanges of traditional Chinese medicine periodicals / 国际中医中药杂志

By conducting exchanges of international periodicals,the author graphically categorized publishing information of Taiwan traditional Chinese medicine periodicals,organizations,relevant websites as well as data base in order to provide readers with information from more aspects.The author wished to raise the awareness of the importance of academic communication from both sides by analyzing conditions for the future cooperation between both sides of the Taiwan Straits.This study aimed to stimulate the development of scientific research and of the cause of traditional Chinese medicine by utilizing resources.

Effect of Lead Pollution on Health of Residents Living on Highway-sides in Mountain Areas / 环境与健康杂志

Objective To investigate the body burden of lead and the related health effects in the residents living on the highway-sides of the mountain areas in Fujian province,China.Methods Eighty-nine subjects living nearby the highway-sides(exposed group) and 69 subjects far away from the highway(control group) were recruited by stratified random sampling method.Their basic situation and relevant index were investigated with questionnaire;The lead levels of blood and urine were determined by graphite furnace atomic absorption spectrometric method and compared;The temperature,pulse rate and blood pressure were taken to analyze the related health effects;and the influence factors of blood lead levels were analyzed by single factor analysis method,rank correlation analysis method and multiple regression analysis method.Results The blood and urine lead level of exposure group([94.19 26.51),(15.36?7.67)?g/L ]were significantly higher than that of the control group[(62.83?13.33),(7.24?4.62) ?g/L;t=8.981 0、7.766 2,P

A integração entre o Internato Rural e o Programa de Agentes Comunitários de Saúde, relato de um ano de experiência no município de Itabira - MG / Integration of Rural Probation of Medicine and Health Community Agents' Program: report on one year of experience in Itabira, Minas Gerais

Os autores apresentam o trabalho desenvolvido durante um ano pelo Internato Rural da Faculdade de Ciências Médicas de Minas Gerais (FCMMG) nos distritos de lpoema e Senhora do Carmo, município de ltabira. Destacam as atividades de integração entre o Internato Rural e o Programa de Agentes Comunitários de Saúde. Utilizam a assistên- cia pré-natal e a prevenção do câncer de colo uterino como parâme- tros para análise da atenção à saúde da mulher nas localidades assis- tidas. Constatam a realização de 10.758 visitas domiciliares pelos agentes comunitários de saúde e de 2.939 consultas clínicas atendi- das pelos acadêmicos de medicína. Verificam um progressivo aumen- to no número de consultas de pré-natal e de exames de cítologia oncótica do colo uterino. Encerram comentando sobre o programa de saúde da família na prática do Internato Rural.

The authors present the proceedings developed during one year by the Rural Probation of Medicine of the Faculdade de Ciências Médicas de Minas Gerais (FCMMG) in the districts of Ipoema and Senhora do Carmo, in ltabira town. Activities of integration of Rural Probation and Heallth Community Agents' Program are outstanding. They use the prenatal assistence and prevention of carcinoma of the uterine cervix as a parameter to analyse the attention given to woman health on the sites assisted. 10758 domiciliary visits were done by the health community aggents and 2939 clinical appointments by the medicine srudents. Evidence of ptogressive gtowth in the nurnber of prenatal appointments as well as of oncologic cytologycal smears of uterine cervix. They close with cornrnenrs about rhe Family Health Program in the Rural Probation practice.

Influência dos métodos de compensação do erro linear no cálculo da área de poligonais topográficas em terreno ondulado / Linear error methods influenced on topographic area calculation under wavy landscape

Os métodos mais conhecidos e utilizados no cálculo da compensação do erro linear, para a obtenção das projeções compensadas e das coordenadas, com a finalidade de calcular-se a área de uma poligonal, são: (1) compensação pelos lados da poligonal, medidos diretamente no terreno; (2) compensação pelas projeções naturais, calculadas em função das distâncias medidas e dos senos e cossenos dos rumos ou azimutes. O objetivo deste trabalho foi quantificar a diferença na área calculada pelos dois métodos de compensação do erro linear e comparar com os valores máximos admissíveis pelo critério de JORDAN (1957), para terreno ondulado. O uso corrente de um ou outro método não diz, a priori, qual o mais exato. No entanto, mostra que a diferença entre as áreas calculadas, por ambos os métodos, é muito inferior ao valor máximo para o erro em área. estabelecido. Os resultados obtidos para as áreas das poligonais, permitem concluir, que os métodos de compensação estudados, não diferem entre si, de acordo com os critérios normalizados em Topografia.

Linear error compensation methods mainly used compensated projections and coordenates acquisition for poligons area calculation were: (1) poligons sides compensation, directiy measured on terrain; (2) natural projections calculated with measured distances an sine and cosine of courses or azimuthes. The purpose of our study was quantify differences on calculated area by two linear error compensation method and to compare with JORDAN's critério (1957) values for wavy landscape. Use doesn't show which is the most correct method. However differences between calculated area by both methods are a lot of lower área error values tolerable. Poligons areas results demonstrated two different compensation methods can be used accord Topographic standartized critério.

COMPARATIVE STUDY OF TWO IMMUNOELECTRON MICROSCOPICAL DOUBLE LABELLING METHODS APPLYING PROTEIN A-GOLD TECHNIQUE / 解剖学报

In the present study, comparison have been made between two kinds of double labelling methods; single side labelling and both sides labelling. To make the different groups be comparable, all sections were continuously cut from the same specimen and all labelling processes were carried out at the same ti- me. The groups were divided as follows: A, one side anti-?-amylase labelling and one side antitrypsin labelling; B, single side labelling of anti-?-amylase and antitrypsin; C, one incubation with anti-?-amylase, followed by two incu- bations with protein A-gold (PAG) complexes of varied size, C1: 7nm and 20nm, C2: 10nm and 20nm, C3: 20nm and 7nm; D, single side labelling of anti- ?-amylase and an unrelated antiserum (antichathepsin D), applying free protein A between two labellings; E, as C, but with free protein A between two PAG incubations; F, as control. Group A and B showed that the two labelling me- thods had almost the same sensitivity.Group C indicated that the interaction of single side labelling were resulted from the combination of the second PAG with the free Fc region of the first antiserum. To decrease the interaction, it was necessary for the second PAG to be much larger than the first one.Group D de- monstrated that the interaction between the second antiserum and the first PAG was very feeble. Group E proved that free protein A could completely prevent the interaction of single side labelling method. The both sides labelling method avoids interaction, but mistakes resulting from the ultrastructural differences on two sides of the sections may happen. Which method to be selected is dependent upon what to be labelled.

EFFECT OF TOTAL GLUCOSIDES OF PAEONY ON LEUKOTRIENE B_4 BY PERITONEAL MACROPHAGES IN RATS / 中国药理学通报

Total glucosides of paeony ( TGP ) , an extract of Paeonia Lacti-flora Pall were investigated for its effect on the synthesis of leukotriene B_4 ( LTB_4 ) by peritoneal macrophages ( PM?). LTB4, generated by 10~9~15 ? 10~10/L PM? with ionophore A_23187 , were measured with RP-HPLC. Suppression of releasing LTB_4 from PM? by TGP ( 100 mg/L ) was as much as the same dose of Flufenamic acid, but the action of TGP was slower. TGP significantly inhibited the synthesis of LTB_4 by PM? in a dose-dependent manner. The concentration of TGP required to obtain 50% inhibition ( IC_50 ) of formation of LTB_4 was 0.66mg/L. The data suggested antiinflam-matory and immunomodulatory action of TGP were related to its suppression of releasing LTB_4