Quantitative evaluation of lumbar spine osteoporosis by apparent diffusion coefficient and signal intensity ratio of magnetic resonance diffusion-weighted magnetic resonance imaging / 中国骨伤

OBJECTIVE@#To investigate the application value of apparent diffusion coefficient (ADC) and signal intensity ratio (SIR) of MR diffusion-weighted imaging (DWI) in quantitative evaluation of lumbar spine osteoporosis.@*METHODS@#A total of 175 patients with lumbar spine diseases who received dualenergy X-ray absorption (DXA) bone mineral density (BMD), routine MRI and DWI of the lumbar spine from May 2017 to October 2019 were selected. According to the T-value of DXA, the patients were divided into osteoporosis group (64 cases), osteopenia group (53 cases) and normal bone mass group (58 cases). The ADC and SIR values of L@*RESULTS@#There were statistically significant differences in ADC and SIR values among three groups (@*CONCLUSION@#ADC and SIR can better reflect the BMD of patients with lumbar diseases, and can quantitatively evaluate the vertebral body of osteoporosis, which play an important role in the diagnosis of lumbar osteoporosis.

The value of MRI IDEAL technique in the etiological analysis of vertebral compression fracture / 实用放射学杂志

Objective To discuss the differential value of magnetic resonance asymmetric echo threeGpoint waterGfat separation technique (IDEAL)in benign and malignant vertebral compression fractures.Methods 48 cases of vertebral compression fractures patients (85 vertebrals)were performed conventional MRI and IDEAL scanning at 1.5T superconducting MR scanner (GE Brivo 355 MR system).25 benign and 23 malignant vertebral compression fracture cases were enrolled in this study.25 benign cases(42 vertebrals)included 8 pure traumatic fractures,16 osteoporosis and 1 tuberculosis respectively,while 23 malignant cases (43 vertebrals)included 22 metastases and 1 myeloma respectively.The signal intensity ratios(SIR)of the benign and malignant vertebral in waterGfat imaging and that of inGphase and outGphase (fatty signal intensity/water signal intensity and outGphase signal intensity/inGphase signal intensity respectively),and namely SIR were measured and calculated.SIR in the 4 groups were statistically analyzed.Results WaterGfat SIR of benign vertebral compression fracture was 0.67±0.19,whereas in malignant vertebral compression fractures was 0.14±0.07,and the difference was statistically significant (t＝1 2.6 2 ,P＜0.05 ).SIR of outGphase signal intensity/inGphase signal intensity of benign vertebral compression fracture was 0.52±0.25,whereas in malignant vertebral compression fracture was 0.83±0.07,and the difference was statistically significant (t＝－7.2 9 ,P＜0.05).Conclusion The SIR of malignant group is significantly lower than that of benign group in waterGfat imaging. whereas the SIR of malignant group is higher than that of benign group in inGphase and outGphase imaging.There is no overlap of SIR between benign and malignant in waterGfat imaging and inGphase and outGphase imaging.IDEAL technique has a high application value in the identification of benign and malignant vertebral compression fractures,which is worth popularizing.

The value of the signal intensity ratio of the extraocular muscle and the ipsilateral white matter of the MRI in the evaluation of the activity of thyroid-associated ophthalmopathy / 中华内分泌代谢杂志

Objective To investigate the quantitative value of the signal intensity ratio of extraocular muscle and ipsilateral white matter measured by MRI for the evaluation of activity in thyroid-associated ophthalmopathy. Methods A total of 129 patients and 245 eyeballs with thyroid-associated ophthalmopathy were enrolled in this study and this 245 eyeballs were set as thyroid-associated ophthalmopathy group(TAO group). There were 10 patients with newly diagnosed Graves'disease and in the same period and these 20 eyeballs were set as graves'disease group(GD group). 32 normal people from annual physical test excluded thyroid and eye diseases and their 64 eyes were selected randomly for the normal control group(NC group). The signal intensity of the extraocular muscle and the ipsilateral white matter on the MRI images were measured, while did exophthalmos and the width of the inner fat of eyeballs (FWs)measurements in the same time. Results SIR,FWs,and exophthalmos of TAO group were higher than those of the other 2 groups[SIRs:1.71(1.40,2.10)vs 1.26(1.22,1.34)and 1.23(1.14,1.32);FWs:8.04(6.70, 8.71)mm vs 6.16(4.86,7.08)mm and 6.93(6.41,7.65)mm,exophthalmos:20.10(18.56,22.15)mm vs 15.40(14.87,16.60)mm and 14.73(13.40,16.07)mm,all P<0.05]. The reference value of SIR establishing based on SIRs of NC group is less than 1.37. In total 129 TAO patients,55 patients(with 106 eyeballs)have a clinical activity score(CAS). Then,these eyeballs were grouped to activity and non-activity(grouped by CAS≥3),and the baseline group difference of these 2 groups was not statistically significant. The SIRs and exophthalmos of activity group were higher than the non-activity group[SIRs:1.70(1.45,2.33)vs 1.41(1.25,1.75); exophthalmos:(20.38 ± 2.40)mm vs(19.05 ± 3.70)mm,all P<0.05]. But the difference of FWs of these two groups was not statistically significant(P>0.05). The SIRs and CAS had a positive correlation(r=0.580,P=0.000),through the receiver operating characteristic curve(ROC)we get the best diagnostic performance of TAO activity when the SIR≥1.56(sensibility=65.6%,specificity=89.1%,AUC=0.815,P=0.000). Conclusion The signal intensity ratio of extraocular muscle and ipsilateral white matter may discriminate the activity of TAO early as a quantitative indicator, reflecting its efficacy,and is worth clinically generalizing.