Factores que influyen en el grado de resección y propuesta de escala preoperatoria para el manejo de meningiomas de base de cráneo / Predictive factors in the extent of resection and proposal of a preoperative scale for the management of skull base meningiomas

Objetivos: identificar factores que intervienen en el grado de resección de los meningiomas de base de cráneo y proponer una escala para calcular la probabilidad de resección total. Materiales y métodos: estudio unicéntrico, observacional, retrospectivo, de pacientes operados en el período 06/2018 ­ 06/2022. Se utilizaron como variables: edad, clínica, localización, tamaño, embolización previa, edema perilesional, calcio intratumoral, características en T2 y T1 e invasión ósea. El grado de resección se midió con la clasificación de Simpson tradicional y también se dividió en resección total (Simpson I, II y III) y subtotal (Simpson IV y V). Con los resultados se propuso una escala teniendo en cuenta las variables con significación estadística (p < 0.05). Se realizó una revisión bibliográfica del tema. Resultados: Se operaron un total de 23 pacientes. Fueron estadísticamente significativas asociadas con el grado de Simpson, la localización (p 0,002) y el tamaño (p 0,001). Asociada con resección total y subtotal, la invasión ósea (p 0,013). Para la escala utilizamos: localización (anterior 1 punto, posterior 2 puntos, medial 2 puntos y medial que involucra seno cavernoso 3 puntos), tamaño (<5 cm 1 punto, >5 cm 2 puntos) e invasión ósea (no 1 punto y si 2 puntos). Realizamos un análisis inferencial y se observó asociación entre la escala realizada y el grado de resección (p 0,005). Conclusión: En nuestro estudio se observó una asociación entre el tamaño, la localización y la invasión ósea con el grado de resección conseguido. Propusimos una escala para medir la probabilidad de resección total(AU)

Objectives: identify factors that intervene in the degree of resection of skull base meningiomas and propose a scale to calculate the probability of total resection. Materials and methods: single-center, observational, retrospective study of patients operated in the period 06/2018 - 06/2022. The following variables were used: age, symptoms, location, size, previous embolization, perilesional edema, intratumoral calcium, characteristics in T2 and T1 and bone invasion. The degree of resection was measured using the traditional Simpson scale and was also divided into total (Simpson I, II, and III) and subtotal (Simpson IV and V) resection. With the results, a scale was proposed taking into account the variables with statistical significance (p < 0.05). A bibliographic review of the subject was carried out. Results: A total of 23 patients were operated. They were statistically significant associated with Simpson's grade the location (p 0.002) and size (p 0.001). Associated with total and subtotal resection, the bone invasion (p 0.013). For the scale we use: location (anterior 1 point, posterior 2 points, medial 2 points and medial involving the cavernous sinus 3 points), size (<5 cm 1 point, >5 cm 2 points) and bone invasion (no 1 point and yes 2 points). We performed an inferential analysis and an association was observed between the scale used and the degree of resection (p 0.005). Conclusion: In our study, an association was observed between the size, location and bone invasion with the degree of resection achieved. We proposed a scale to measure the probability of total resection(AU)

A single center retrospective study on hospitalization information for 812 cases of very low birth weight and ex-tremely low birth weight infants / 中华实用儿科临床杂志

Objective To analyze the survival rate and hospitalization information for 81 2 cases of very low birth weight (VLBW)and extremely low birth weight (ELBW)infants.Methods The retrospective study was con-ducted in a single center,Department of Neonatology,Hubei Women and Children Hospital,from January 2009 to De-cember 201 4,where the data of 81 2 infants with birth weight(BW)less than 1 500 g was analyzed in regard to perinatal condition,treatment and complications of these in relation to prognosis.Results (1 )A total of 621 cases(76.5%) had favorable prognosis.(2)There was a significant difference in the favorable prognosis rate between different BW groups (χ2 =28.87,P <0.05)and different gestational age(GA)groups (χ2 =1 4.77,P <0.05).The favorable prog-nosis rate for the male infants(χ2 =4.69,P <0.05),puerpera age between 1 7 -25 and 36 -46 years old (χ2 =1 1 .1 9, P <0.05),usage of prenatal hormones(χ2 =8.02,P <0.05),the infants without intrauterine infection (χ2 =8.61 ,P <0.05),the mother without gestational hypertension (χ2 =7.20,P <0.05)and gestational diabetes mellitus(χ2 =1 9.2, P <0.05)were different compared to the control groups.(3)Infants with peripherally inserted central catheter (PICC) (χ2 =33.31 ,P <0.05)and recovery birth weight within 1 0 days(χ2 =29.65,P <0.05)had higher favorable prognosis rate compared to the control groups,which had significant differences.(4)Infants with intraventricular haemorrhage (IVH)(χ2 =1 3.1 6,P <0.05),respiratory distress syndrome (RDS)(χ2 =7.59,P <0.05),necrotizing enterocolitis (NEC)(χ2 =1 3.02,P <0.05)and serious asphyxia (χ2 =6.05,P <0.05)had lower favorable prognosis rates than those did not,with significant differences.(5)Logistic analysis:the lower BW,smaller GA,earlier birth,unused PICC, serious asphyxia,IVH,RDS were risk factors for poor prognosis(all P <0.05).Conclusions The favorable prognosis rate of VLBW and ELBW infants has improved gradually,and is closely related to GA,BW,maternal age,perinatal care,prevention complication,treatment of disease and social factors etc.