First description of basaloid carcinoma of the canine mammary gland: case report / Primeira descrição do carcinoma basaloide da glândula mamária canina: relato de caso

The objective of this case report was to describe histopathological and immunohistochemical characteristics of the first reported basaloid carcinomas in the canine mammary gland. Two bitches were treated for tumors in the mammary gland and underwent mastectomy. Microscopic evaluation of these tumors revealed epithelial cells arranged in a predominantly solid pattern with hyperchromatic peripheral cells arranged in a palisade pattern. Metastases in regional lymph nodes were found in both animals, and one bitch exhibited pulmonary metastasis. Immunohistochemistry revealed positive labeling for the basal cell markers cytokeratin 14 and p63. Histopathological and immunohistochemical findings led to diagnoses of basaloid carcinoma of the canine mammary gland with regional and distant metastasis.(AU)

O objetivo deste relato de caso é descrever as características histopatológicas e imuno-histoquímicas do primeiro relato de carcinoma basaloide na glândula mamária canina. Duas cadelas foram atendidas com tumores na glândula mamária e foram submetidas à mastectomia. A avaliação microscópica demonstrou células epiteliais arranjadas em um padrão predominantemente sólido, com células periféricas hipercromáticas, dispostas em paliçada. As duas apresentaram metástase em linfonodos regionais e uma delas metástase pulmonar. A imuno-histoquímica revelou marcação positiva para citoqueratina 14 e p63, marcadores de células basais. Achados histopatológicos e imuno-histoquímicos levaram ao diagnóstico de carcinoma basaloide da glândula mamária canina com metástase regional e a distância.(AU)

Carcinoma papilar pancreático sólido y quístico / Solid and cystic pancreatic papillary carcinoma

Paciente femenina de 22 años. Quince días antes del ingreso comenzó con dolor en el hemiabdomen superior que se intensificaba con la ingestión de alimentos, acompañado de sensación de plenitud. Se encontraron niveles de amilasa sérica dentro de límites normales. Los estudios imagenológicos, tanto la ecografía como tomografía axial computarizada, revelaron una masa tumoral en la cola del páncreas de contornos bien definidos y vascularizados. Se intervino quirúrgicamente y se realizó la exéresis total de la lesión. El estudio anátomo-patológico confirmó que se trataba de un carcinoma papilar pancreático sólido y quístico. Posteriormente, la paciente recibió tratamiento con quimioterapia y radioterapia. Los exámenes imagenológicos evolutivos no mostraron recidivas locales, ni metástasis a distancia. La paciente ha tenido buena respuesta al tratamiento y hoy conserva buen estado de salud.

A 22 years-old female patient who began feeling some pain in the upper hemiabdomen that became intensive after food consumption and the feeling of having eaten too much. The serum amylase levels were within the normal limits. The imaging studies both echography and computerized axial tomography disclosed a well-defined and vascularized tumor mass in the tail of pancreas. She was operated on to completely remove the lesion. The anatomopathological study confirmed the diagnosis of solid and cystic pancreatic papillary carcinoma. Later on, the patient received chemotherapy and radiotherapy. The evolutional imaging tests did not show either local relapses or distant metastasis. The patient responded well to treatment and her health status is good nowadays.