Perception of first-order grating acuity and second-order spatial contrast sensitivity in anisometropia amblyopia / 国际眼科杂志(Guoji Yanke Zazhi)

AIM: To study the perception of first-order grating acuity and second-order spatial contrast sensitivity in patients with monocular anisometropia amblyopia.METHODS:A total of 715 children(715 eyes)diagnosed as monocular anisometropia amblyopia in our hospital from January 2018 to December 2022 were collected as amblyopia group, and 745 children(745 eyes)with normal corrected visual acuity were collected. The best corrected visual acuity(BCVA), first-order grating acuity and/or second-order spatial contrast sensitivity were measured, repectively. The perception ability of amblyopia patients to first-order grating acuity and second-order spatial contrast sensitivity were analyzed.RESULTS:There were significant differences between amblyopia group and normal control group in the perception of first-order grating acuity(11.58±6.10 vs. 20.27±3.47, P<0.001)and second-order spatial contrast sensitivity(0.33±0.16 vs 0.12±0.04, P<0.001). And there were significant differences between mild-to-moderate amblyopia and severe amblyopia patients in first-order grating acuity(12.10±6.23 vs. 8.13±3.70, P<0.001)and second-order spatial contrast sensitivity(0.32±0.16 vs. 0.37±0.17, P<0.05).CONCLUSION: The first-order and second-order visual pathway of the cerebral cortex in children with monocular anisometropia amblyopia have different degrees of damage. The injury of severe amblyopia is more serious than that of mild-to-moderate amblyopia.

Research progress on visual defects of amblyopia / 中华实验眼科杂志

Amhlyopia is a developmental disorder of visual system caused by abnormal visual experiences in critical period,whose characteristic is low monocular or binocular best corrected visual acuity and without ocular organic lesions.With the development of the research,more and more studies showed that amblyopia can not only lead to a reduction in corrected visual acuity,but also accompany by many other visual defects,such as visual crowd effect,impaired spatial contrast sensitivity,decreased vernier acuity,contour integration deficit,orientation discrimination deficit,temporal processing deficit and global processing deficit,which has become a common concern of a social problem.A comprehensive understanding of visual defects in amblyopia is of great significance on the diagnosis and treatment of amblyopia.This paper summarized the research progress of various visual defects of amblyopia,so as to provide references for the clinical diagnosis and treatment of amblyopia.