Research on the Ethical Supervision of Human Gene Editing Technology: Based on the Perspective of Game Theory / 中国医学伦理学

In view of the current norms and demands of human gene editing technology at home and abroad, the paper explained that the regulatory difficulties faced by human gene editing technology were due to the conflict between economic interests and moral bottom line by constructing a game model in a hypothetical way. On this basis, the ideas of the supervision mode of human gene editing technology were put forward: establish unified international standards based on the country as the main body, enact more stringent and effective laws, to jointly deal with the behavior of genetic manipulation of human gametes, zygotes and embryos for the purpose of reproductive, and ensure the normalization and legalization of gene editing technology to avoid technology abuse.

Investigation about the present status of renal replacement therapy in department of intensive care unit in Tianjin / 中华危重病急救医学

Objective:To understand the current state of renal replacement therapy (RRT) in intensive care unit (ICU) of Tianjin public hospital, and to provide scientific evidence and direction for homogenized management and overall level improvement of RRT in Tianjin.Methods:The questionnaires were distributed to the chief or key staff of 33 ICUs from 32 public hospitals in Tianjin by clinical quality control center for critical care medicine of Tianjin and ICU of Tianjin Third Central Hospital. The RRT data of ICUs from January 2020 to December 2021 was collected, including the type and size of ICU, the number of patients undergoing RRT, reasons for initiating RRT, the RRT modes, the anticoagulation and the complications of RRT and so on.Results:A total of 33 valid questionnaires were obtained, with a recovery rate of 100%. The result showed that there were 38 803 patients admitted to the selected ICUs during investigation, and 5 456 of them (14.06%) received RRT. In most ICUs, the reasons of initiating RRT were renal failure, sepsis and volume overload. The mode of RRT was mainly continuous venovenous hemofiltration (CVVH), which was followed by continuous venovenous hemodiafiltration (CVVHDF). Carbonate replacement fluid was the first choice. Heparin was the dominant anticoagulant, and there was an increasing trend in the use of citrate anticoagulation simultaneously. However, heparin-free anticoagulation used mostly in bleeding patients. Overall, the RRT modes and anticoagulation methods were single. Thrombosis was the main iatrogenic factor interrupting RRT in most ICUs, and also the reasons for complications related to catheter or circulation pipeline. It still showed an ineffective anticoagulation of RRT even after increasing the dosage of anticoagulants.Conclusions:RRT is an important organ support method in ICU, which has been widely carried out in ICUs of Tianjin and continues to expand. Despite the positive performance, it still needs to be improved and standarized in some aspects, such as the diversification of RRT modes, anticoagulation, and the complication prevention.

Expert recommendation for operational norms of laparoscopic radical resection of perihilar cholangiocarcinoma / 中华外科杂志

Radical resection is the only curable treatment for perihilar cholangiocarcinoma.With the continuous renewal of laparoscopic instruments and the continuous improvement of technology, laparoscopic radical resection of perihilar cholangiocarcinoma has been gradually carried out in China, and its feasibility and safety have been recognized by some domestic peers. In order to standardize clinical diagnosis and treatment behavior, ensure patients receive safe and standardized treatment and improve prognosis, so that the operation can be standardized application and development. Based on the principles of treatment of perihilar cholangiocarcinoma and the corresponding technical norms of laparoscopic operation, the Expert Group on Operational Norms of Laparoscopic Radical Resection of Perihilar Cholangiocarcinoma and Editorial Board of Chinese Journal of Surgery have organized relevant domestic experts to formulate expert recommendations for laparoscopic radical resection of perihilar cholangiocarcinoma, so as to facilitate clinical practice and standardized application.

Expert recommendation for robot-assisted esophagectomy (2019 edition) / 中华外科杂志

Minimally invasive esophagectomy for the surgical treatment of esophageal cancer has gradually been recognized and applied. With the application of robot-assisted technology in esophageal surgery, robot-assisted esophagectomy has been carried out in large domestic centers, and its feasibility and safety have been recognized by some domestic experts. In view of no advice or guidelines about robot-assisted esophagectomy has been written before, Committee of Esophageal Cancer in China Anticancer Association organized relevant domestic experts to establish this expert recommendation for standardization of robot-assisted esophagectomy, aiming at helping surgeons perform this complex procedure safely.

Expert recommendation for operational norms of laparoscopic radical resection of perihilar cholangiocarcinoma / 中华外科杂志

Radical resection is the only curable treatment for perihilar cholangiocarcinoma.With the continuous renewal of laparoscopic instruments and the continuous improvement of technology, laparoscopic radical resection of perihilar cholangiocarcinoma has been gradually carried out in China, and its feasibility and safety have been recognized by some domestic peers. In order to standardize clinical diagnosis and treatment behavior, ensure patients receive safe and standardized treatment and improve prognosis, so that the operation can be standardized application and development. Based on the principles of treatment of perihilar cholangiocarcinoma and the corresponding technical norms of laparoscopic operation, the Expert Group on Operational Norms of Laparoscopic Radical Resection of Perihilar Cholangiocarcinoma and Editorial Board of Chinese Journal of Surgery have organized relevant domestic experts to formulate expert recommendations for laparoscopic radical resection of perihilar cholangiocarcinoma, so as to facilitate clinical practice and standardized application.

Expert recommendation for robot-assisted esophagectomy (2019 edition) / 中华外科杂志

Minimally invasive esophagectomy for the surgical treatment of esophageal cancer has gradually been recognized and applied. With the application of robot-assisted technology in esophageal surgery, robot-assisted esophagectomy has been carried out in large domestic centers, and its feasibility and safety have been recognized by some domestic experts. In view of no advice or guidelines about robot-assisted esophagectomy has been written before, Committee of Esophageal Cancer in China Anticancer Association organized relevant domestic experts to establish this expert recommendation for standardization of robot-assisted esophagectomy, aiming at helping surgeons perform this complex procedure safely.

Making the Concept Standard Is the Base of Development of Theory of TCM / 浙江中医药大学学报

It was pointed out that the development of theory of TCM was restricted by the indistinct concepts.The advantages and disadvantages of the concept between traditional Chinese medicine and western medicine were analyzed.Basing on literature researches and modern science researches can solve the concept problems of the theory of TCM.

Design and Application of Oral Prescription Drug Labels in Hospital Pharmacy / 中国药房

OBJECTIVE:To further standardize oral prescription drug labels in hospital pharmacy. METHODS: The prescription drug labels were specially made based on drug package inserts. RESULTS & CONCLUSIONS: The new oral prescription drug labels contain more information in which drug usage has been clearly identified thus helpful for pharmacists to reduce dispensing errors, the related information of medicines are available. Carrying out rational drug use and pharmaceutical care services plays a key role for the safe, effective and rational drug use.

Great attention to the standard training and certification system for interventional neuroradiologist / 介入放射学杂志

During the past decades, interventional neuroradiology has become one of the most important modalities for treatment of cerebral vascular diseases. Chinese doctors have made great progress in this field, and their diagnosis and treament have also reached the international level in some territories. Following the need of specialized development for interventional neuroradiology,more and more problems have arisen and even caused argument in this field. To resolve the issue and promote the healthy and fast development of interventional neuroradiology,it is time for us to formulate the standard training and certification system for interventional neuroradiologist.

The standardized research of nomenclature and classification of rheumatism / 中华中医药杂志

The nomenclature of rheumatism is very miscellaneous and varied,seriously influencing academic intercourse and development.In order to standardize the nomenclature and classification,this article,on the basis of studying historical documents and learning from clinical achievements,closely combined clinical practice to research every disease’s name in history corresponding to every patient in clinic.After testing,verifying and comparing repeatedly,these names are now standardized into 4 classes over 60 names from 15 classes over 400 names in history.These new over 60 rheumatism names which are classified after taking view of cause,site,symptom,and characteristics of disease possess scientific and practical value.

Some Suggestions on Reasonably Standardizing the Structure of the Institutional Ethics Committee for Organ Transplantation in China / 中国医学伦理学

It is the prerequisite and foundation to set up the institutional ethics committee of organ transplantation that holds a proper structure for ethics committee to play a key role effectively.In terms of our reality and based on the successful practices and guidelines of international organizations of ethics committee,some suggestions and guidelines on reasonably standardizing the structure of ethics committee for organ transplantation in China are given to guarantee ethics committee to fulfill its target functions.