Establishment and implementation effect of rapid response medical team for extracorporeal cardiopulmonary resuscitation in emergency department / 中华急诊医学杂志

Objective:To retrospectively analyze the establishment and implementation effect of ECPR rapid response medical team in emergency department, and to explore a more efficient rescue mode.Methods:A total of 41 patients who started ECPR in the emergency room of a tertiary hospital in Beijing from November 2017 to September 2022 were selected as subjects. The 14 patients treated by the ECPR rapid response medical team in the emergency department were set as the experimental group, and the 27 patients treated by the ECPR team of the MDT mode led by the cardiac surgeon were set as the control group. The ECPR start-up time, pipeline pre-filling time, ECPR start-up to ECMO successful operation time, complication rate and treatment success rate were compared between the two groups.Results:There was no significant difference in the outcome between the two groups (all P>0.05), but the total time (min) of ECPR implementation by the rapid response medical team in the emergency department was shorter (20.86 ± 10.86 vs. 23.04 ± 11.40), the incidence of complications was lower, and the success rate of treatment was higher (28.57 % vs. 25.93 %). Conclusion:Establishing a mature ECPR rapid response team dominated by emergency medical care helps improve the rescue coordination and work efficiency, thereby providing the emergency protection and management of full -chain for the treatment of critical condition.

As startups no contexto da organização capitalista financeira e as subjetividades empreendedoras / Startups in the context of financial capitalist organization and entrepreneurial subjectivities / Startups en el contexto de la organización capitalista financiera y subjetividades emprendedoras

As startups são empresas que apresentam modelos de negócios marcados pela inovação, rapidez, flexibilidade e alta capacidade de adaptação aos mercados. Atuando em diferentes setores socioeconômicos, elas prometem criar e transformar produtos e serviços. A emergência e disseminação dessas empresas ocorrem em um momento histórico de mudanças iniciadas a partir de 1970 e marcadas pelas crises geradas com o esgotamento do paradigma da sociedade urbano industrial. No Brasil, o número desse modelo de negócio apresentou uma expansão expressiva, alcançando a marca de 13.374 nos últimos cinco anos. Atento a esse cenário, o objetivo desta pesquisa consistiu em compreender como sujeitos, grupos e instituições atribuem sentidos à experiência de trabalho nas chamadas startups. Na parte teórica, as condições sociais e econômicas que possibilitaram a emergência e disseminação das startups são analisadas em uma perspectiva crítica. A parte empírica, por sua vez, apresenta depoimentos de empreendedores relatando o contexto geral de atuação nas startups. Ao final deste artigo, conclui-se que há uma instrumentalização capitalística de componentes subjetivos específicos selecionados e colocados em circulação para fortalecer o modo de produção capitalista financeirizado.(AU)

Startups are companies that have business models characterized by innovation, speed, flexibility, and a high capacity to adapt to markets. Operating in different socioeconomic sectors, they promise to create and transform products and services. The emergence and dissemination of these companies occur at a historical moment of changes that began from 1970 and are marked by the crises generated by the exhaustion of the paradigm of industrial urban society. In Brazil, the number of businesses in this model showed a significant expansion, reaching 13,374 companies in the last five years. Attentive to this scenario, the objective of this research was to understand how subjects, groups, and institutions attribute meanings to the work experience in so-called startups. In the theoretical part, the social and economic conditions that enabled the emergence and dissemination of startups are analyzed in a critical perspective. The empirical part presents entrepreneurs reporting the general context of action in startups. At the end of this article, it is concluded that there is a capitalistic instrumentalization of specific subjective components that are selected and put into circulation to strengthen the financed capitalist production.(AU)

Las startups son empresas que tienen modelos de negocio marcados por la innovación, la velocidad, la flexibilidad y una alta capacidad de adaptación a los mercados. Desde diferentes sectores socioeconómicos, las startups prometen crear y transformar productos y servicios. La aparición y difusión de estas empresas se produce en un momento histórico de cambios que comenzó a partir de 1970 y que está marcado por crisis generadas por el agotamiento del paradigma de la sociedad urbana industrial. En Brasil, estas empresas se expandieron significativamente alcanzando la marca de 13.374 empresas en los últimos cinco años. En este escenario, el objetivo de esta investigación fue entender cómo los sujetos, grupos e instituciones atribuyen significados a la experiencia laboral en las startups. En la parte teórica, se analizan las condiciones sociales y económicas que permitieron el surgimiento y la difusión de las startups en una perspectiva crítica. La parte empírica presenta testimonios de emprendedores que informan sobre el trabajo en startups. La investigación concluye que hay una instrumentalización capitalista de componentes subjetivos específicos que se seleccionan y ponen en circulación para fortalecer el modo de producción capitalista financiero.(AU)

Healthcare Innovation Lifecycle and Policy Ecosystem: Insights from India.

Purpose: Healthcare innovations are one of the drivers of healthcare sector growth in India. Innovation policies are challenging because of the uncertainty regarding the outcome of the innovations. Hence, there is a need to understand the interface between policies and healthcare innovations to identify gaps and propose timely recommendations. Acoordingly, this study uses the Indian healthcare startup sector as a case study to analyse the above linkages, gaps and propose recommendations. Methodology: Quantitative data from the startup India portal along with qualitative data from key informant interviews have been analysed to draw insights. Findings: Healthcare startups have made significant contributions to the economy and healthcare sector, but there are gaps and room for improvement especially in the areas of awareness, funding and mentoring. Conclusions: Based on the study findings a conceptual framework has been created for understanding the nature of gaps and their linkages in the healthcare innovation lifecycle.

O impacto da ansiedade em informação nas Startups de Inovação / La información como un recurso de ansiedad en las organizaciones / Information as a source of anxiety in organizations

O presente trabalho tem como objetivo identificar o impacto da informação no contexto da construção de conhecimento em trabalhadores de startups. Nesse sentido, ao observarmos o atual cenário das organizações, analisamos que a informação é capaz de modificar o comportamento dos sujeitos de diferentes maneiras. Dessa forma, ao mesmo tempo em que devemos considerar a informação como um recurso para as organizações, também é necessário compreender o seu impacto na saúde geral dos trabalhadores, que vai desde a sensação de incapacidade em absorver múltiplas informações na produção de conhecimento, entre outros problemas (doenças somáticas, síndrome de esgotamento etc.), o que interfere na saúde mental, tanto quanto à saúde física. O uso da informação provoca inúmeros desencadeamentos nas organizações, todavia, destacamos um comportamento desenvolvido pelos trabalhadores que necessita ser analisado: a ansiedade informacional. Diante desse cenário, a presente pesquisa buscou compreender o comportamento informacional dos trabalhadores do conhecimento nas startups. Para tanto, foi escolhido o método 'estudo de caso', aplicando-se a triangulação, ou seja, aplicando diferentes técnicas de coleta e análise de dados, tornando a pesquisa mais consistente, validando assim os dados e análises realizadas. A população da pesquisa consiste em 18 sujeitos de 4 diferentes empresas de tecnologia da informação que foram enquadradas como startups. Com as informações colhidas, foi possível construir parâmetros baseados em estratégias de Gestão de Pessoas de Ribeiro et al (2019) capazes de minimizar o impacto da ansiedade em informação nos trabalhadores dessas startups(AU)

Este documento tiene como objetivo identificar el impacto de la información en el contexto de la creación de conocimiento en los trabajadores de nuevas empresas. En este sentido, al observar el escenario actual de las organizaciones, analizamos que la información puede modificar el comportamiento de los sujetos de diferentes maneras. Por lo tanto, si bien debemos considerar la información como un recurso para las organizaciones, también es necesario comprender su impacto en la salud general de los trabajadores desde la sensación de incapacidad para absorber información múltiple en la producción de conocimiento; entre otros problemas, enfermedades somáticas, síndrome de agotamiento, etcétera, que interfieren con la salud mental y la salud física. El uso de la información causa numerosos factores desencadenantes en las organizaciones; sin embargo, destacamos un comportamiento desarrollado por los trabajadores que debe analizarse: la ansiedad informativa. Dado este escenario, la presente investigación buscó comprender el comportamiento informativo de los trabajadores del conocimiento en las nuevas empresas. Para esto, se eligió el método "estudio de caso", aplicando la triangulación, es decir, diferentes técnicas de recolección y análisis de datos, haciendo que la investigación sea más consistente, para validar los datos y el análisis realizado. La población de la investigación consistió en 18 sujetos de 4 compañías diferentes de tecnología de la información que fueron clasificadas como startups. Con la información recopilada, fue posible construir parámetros basados ​​en las estrategias de gestión de personas de Ribeiro y otros (2019), capaces de minimizar el impacto de la ansiedad por la información en los trabajadores de estas nuevas empresas(AU)

The purpose of the study was to identify the impact of information in the context of knowledge creation among workers from startup enterprises. Based on observation of the current scenario of organizations, we analyzed the fact that information may modify the behavior of subjects in different ways. Thus, while we should consider information as a resource for organizations, we should also understand its impact on workers' general health in terms of a feeling of inability to grasp multiple information in the process of knowledge production. Among other problems, somatic diseases and the burnout syndrome interfere with mental and physical health. Given this scenario, the study aimed to understand the information behavior of knowledge workers in the new enterprises. To achieve this goal, the case study method was applied, which included the use of triangulation, i.e. different data collection and analysis techniques contributing greater consistency to the study when validating the data and the analysis performed. The study population was 18 subjects from 4 different information technology companies classified as startups. With the information collected, parameters could be constructed on the basis of the people management strategies developed by Ribeiro et al (2019), capable as they are of minimizing the impact of information anxiety among workers from these new enterprises(AU)

Research Advances in the Action of Toll-like Receptor 2 in Acupuncture Information Start-up and Conduction Mechanism / 上海针灸杂志

This article summarizes the literature about studies onToll-like receptor 2and acupuncture points and explores thecorrelationand action of Toll-like receptor 2inacupuncture information start-up and conduction mechanism from the biological characteristics of Toll-like receptor 2and the relationship of Toll-like receptor 2-mediated signal pathways tomast cells, acupuncture effects and the immuno-neuro-endocrine network.

Biomethane production from vinasse in upflow anaerobic sludge blanket reactors inoculated with granular sludge

ABSTRACT The main objective of this study was to evaluate the anaerobic conversion of vinasse into biomethane with gradual increase in organic loading rate (OLR) in two upflow anaerobic sludge blanket (UASB) reactors, R1 and R2, with volumes of 40.5 and 21.5 L in the mesophilic temperature range. The UASB reactors were operated for 230 days with a hydraulic detection time (HDT) of 2.8 d (R1) and 2.8-1.8 d (R2). The OLR values applied in the reactors were 0.2-7.5 g totalCOD (L d)−1 in R1 and 0.2-11.5 g totalCOD (L d)−1 in R2. The average total chemical oxygen demand (totalCOD) removal efficiencies ranged from 49% to 82% and the average conversion efficiencies of the removed totalCOD into methane were 48-58% in R1 and 39-65% in R2. The effluent recirculation was used for an OLR above 6 g totalCOD (L d)−1 in R1 and 8 gtotalCOD (L d)−1 in R2 and was able to maintain the pH of the influent in R1 and R2 in the range from 6.5 to 6.8. However, this caused a decrease for 53-39% in the conversion efficiency of the removed totalCOD into methane in R2 because of the increase in the recalcitrant COD in the influent. The largest methane yield values were 0.181 and 0.185 (L) CH4 (gtotal COD removed)−1 in R1 and R2, respectively. These values were attained after 140 days of operation with an OLR of 5.0-7.5 g totalCOD (L d)−1 and total COD removal efficiencies around 70 and 80%.

Biofilm formation for organic matter and sulphate removal in gas-lift reactors

A start-up strategy was presented and evaluated to obtain a well-established biofilm in a gas lift-reactor capable both for the removal of organic matter and sulphate. Pumice stone was used as material support. The influence of shear forces, given by the biogas recirculation, the effect of the COD/SO4-2 ratio and the OLRs increase were evaluated on the reactor performance. From the first stages, cell colonization was observed along with the presence of extracellular polymeric substances. The COD and sulphate removal was over 70 percent, for all conditions. The increase of gas flow did not have an adverse effect on biofilm development even though there was some detachment. Specific methanogenic activity of the biofilm increased along the experiments. Operational parameters as alkalinity and alkalinity ratio were within the recommended values for the operation with sulphate-rich wastewater. For gas-lift reactors operation it becomes fundamental to have a suitable start-up strategy that takes into account the initial biofilm development from a non-acclimatized biomass.

Startup flow of nurse workstation / 医疗卫生装备

Nurse workstation, a typical client program of "No.1 Military" project, is trailed and speculated with Oracle tools such as TOAD, and then the general startup flow mode for "No.1 Military" project can be determined, which is instructive for its maintenance and programming.