Isolated Left Trochlear Nerve Palsy Caused by Sphenoid Sinus Mucocele / 대한이비인후과학회지

Paranasal sinus mucoceles are an uncommon cause of isolated palsies of cranial nerves III, IV, and VI. The trochlear nerve has been reported to be less frequently affected than the abducens and oculomotor nerves. Isolated sphenoid sinus diseases may cause serious complications by involving adjacent vital structures such as the optic nerve, cavernous sinus, internal carotid artery, and cranial nerves III–VI. We report a case of a 76-year-old woman who presented to our emergency department with a chief complaint of acute double vision and headache. Her diplopia was diagnosed as left trochlear nerve palsy. Brain CT and MRI revealed expanding cystic lesions in both sphenoid sinuses with bony erosion of the left sinus wall. The patient underwent an endoscopic intranasal sphenoidotomy and recovered completely from diplopia at postoperative 2 months. The relationship between the trochlear nerve palsy and its anatomy is also discussed.

Comparison of Double Maddox Rod Test and Bagolini Striated Lens Test for Superior Oblique Palsy

PURPOSE: We compared the results of the double Maddox rod test (DMRT), which is commonly performed in clinics as a subjective torsion test for superior oblique muscle palsy, with those of the Bagolini striated lenses test (BSLT) in a least dissociating condition to predict the cyclofusional capacity. METHODS: Twenty-five patients with acquired superior oblique muscle palsy were tested for degree of subjective torsion with DMRT and BSLT in primary position and down-gaze in Daegu Catholic University Hospital from May 2014 to March 2015. DMRT was performed in a dark room and BSLT in a lighted room. RESULTS: Mean extorsional degree in primary position was 3.40 ± 2.58° on DMRT and 1.88 ± 2.92° on BSLT, a significant difference (p = 0.000). In down-gaze, mean extorsional degree was 4.16 ± 2.90° with DMRT and 2.40 ± 2.90° with BSLT (p < 0.001). CONCLUSIONS: The subjective torsional measurement with BSLT was significantly smaller than with DMRT, and the cyclofusional capacity in patients with acquired superior oblique palsy was 1.5° in primary position and 1.8° in down-gaze. BSLT is helpful in addition to DMRT and fundus photograph for the evaluation of cyclotropia in patients with superior oblique muscle palsy, and this test may yield clinically important information for predicting the cyclofusional capacity of patients with superior oblique muscle palsy.

A Case of Trochlear Nerve Schwannoma Presenting with Binocular Diplopia

PURPOSE: To report a case of unilateral trochlear nerve schwannoma in a patient without neurofibromatosis. CASE SUMMARY: A 58-year-old male presented with acute onset of diplopia which developed 10 days prior. Alternate prism cover test, ductions and versions and Bielschowsky three-step test were compatible with left superior oblique muscle palsy. High-resolution magnetic resonance imaging showed a 6-mm-sized lobulated mass in the cisternal segment of the left trochlear nerve passing lateral to the brainstem. An additional thin-section gadolinium-enhanced orbit magnetic resonance imaging showed definite enhancement in the entire portion of the lobulated mass, compatible with a trochlear nerve schwannoma. Diplopia was managed conservatively with prism glasses and regular follow-up examinations were recommended without further treatment. CONCLUSIONS: A trochlear nerve tumor should be considered in adults who develop diplopia associated with acquired superior oblique muscle palsy.

The Effect of Inferior Oblique Muscle Transposition in Primary and Secondary Inferior Oblique Muscle Overaction

PURPOSE: To evaluate and compare the effect of transposition of inferior oblique muscle in patients with primary inferior oblique muscle overaction and secondary due to superior oblique muscle palsy. METHODS: The present study included 41 patients (53 eyes), who appeared to have primary or secondary inferior oblique muscle overaction due to superior oblique muscle palsy and received transposition of inferior oblique muscle with at least 3 months of follow-up. Patients were retrospectively analyzed to compare the effect of correction and its prognosis. Inferior oblique muscle overaction was graded as +1 to +4 according to the severity. Successful surgery was defined as postoperative inferior oblique muscle overaction from 0 to +1 and failure as above +2. Hypertropia in primary gaze was also recorded to evaluate the effect of correction. RESULTS: Twenty-six (35 eyes) and 15 (18 eyes) patients with primary and secondary inferior oblique muscle overaction due to superior oblique muscle palsy, respectively, received transposition of inferior oblique muscle. Patients with primary inferior oblique muscle overaction showed correction of 2.1 +/- 0.9 with preoperative inferior oblique muscle overaction of 2.0 +/- 0.7. Patients with secondary inferior oblique muscle overaction showed a correction of 2.3 +/- 0.9 with preoperative value of 2.3 +/- 0.8. Each 3.2 +/- 4.1 prism diopters (PD) and 6.5 +/- 5.3 PD of hypertropia at primary gaze showed correction of 3.0 +/- 7.4 PD and 6.3 +/- 5.1 PD, respectively, in each group. CONCLUSIONS: Primary and secondary inferior oblique muscle overaction due to superior oblique muscle palsy showed no difference in correction of overaction and hypertropia after transposition of inferior oblique muscle. Except for presence of inferior oblique muscle underaction, the correction appears effective with good prognosis.

A Case of Idiopathic Orbital Inflammation Presenting with Isolated Myositis of the Superior Oblique Muscle

PURPOSE: To report a case of idiopathic orbital inflammation presenting with isolated myositis of the superior oblique muscle. CASE SUMMARY: A 57-year-old male presented with pain in his left eye and diplopia for three months. His past history was unremarkable except surgery for a thyroid nodule six months prior. At initial presentation, his corrected vision and intraocular pressure were normal. Biomicroscopy and fundus examination were unremarkable. Nasal side swelling of the left upper eyelid was observed, and 1.5-mm proptosis of the left eye was revealed on exophthalmometry. Two and four prism diopter right hypertropia were noted at up and right-up gaze, respectively. Axial and coronal orbital computed tomography (CT) showed enhancement of isolated superior oblique muscle hypertrophy in the left eye. Systemic work-up was negative for any inflammatory disease. A presumptive diagnosis of isolated myositis of superior oblique muscle was made, and the patient was started on 30 mg of oral prednisolone daily. Pain and diplopia disappeared and proptosis of the left eye decreased to 0.5 mm after one week of treatment. Orbital CT images obtained one month after treatment showed a significant decrease in size of the left superior oblique muscle. The steroid was tapered for two months, and the patient has shown no signs of recurrence for four months after cessation of treatment. CONCLUSIONS: Idiopathic orbital inflammation presenting with isolated myositis of the superior oblique muscle is very rare and has not been previously reported in Korea. A patient presenting with pain and diplopia was diagnosed as having isolated myositis of the superior oblique muscle based on CT scan, and good results were achieved with oral steroid therapy.

Parálisis del músculo oblicuo superior atípica / Atypical paralysis of the superior oblique muscle

Las paresias y parálisis oculomotoras implican todos aquellos procesos susceptibles de producir un déficit parcial o total de los movimientos del globo ocular. La lesión puede estar en cualquier parte del sistema oculomotor que incluye la corteza cerebral, el tronco cerebral, nervios, placa neuromuscular y del propio músculo. Las paresias y/o parálisis del músculo oblicuo superior o IV par craneal constituye una de las más frecuentes en la práctica médica estrabológica, puede ser de etiología congénita o adquirida, se caracteriza por hipertropía que aumenta con la inclinación de la cabeza hacia el hombro del lado del ojo afectado signo de Bielschowsky, anisotropía en V, exciclotropía. Los pacientes con paresias y/o parálisis adquirida muestran diplopía vertical y torsional que aumenta con la mirada hacia abajo, tortícolis con inclinación de la cabeza hacia el lado opuesto del ojo afectado y descenso del mentón. El paciente acude a consulta por presentar diplopía vertical y torsional de 13 años de evolución. Al examen de la motilidad ocular había ortotropía en la Posición Primaria de la Mirada con hiperforia al cover test ojo izquierdo, 10 Dp base inferior por barra de prismas, exciclotropía 5*, tortícolis hacia la derecha y Bielschowsky positivo hacia el lado izquierdo. La impresión diagnóstica fue paresia adquirida del músculo OS izquierdo de etiología no precisada. El tratamiento realizado fue la retroinserción del recto superior del ojo izquierdo 4 mm más el desplazamiento temporal de un 1/4 de la inserción con el objetivo de eliminar la diplopía vertical y torsional y la posición anómala de la cabeza

The oculomotor paresis and paralysis involve all those processes capable of producing partial or total deficit of the ocular globe movements. The injure may be located in any part of the oculomotor system that includes the brain cortex, the brain trunk, nerves, neuromuscular plate and of the muscle. Paresis and/or paralysis of the superior oblique muscle or IV cranial nerve is very frequent in the medical practice for strabismus; it can be congenital or acquired, characterized by hypertropia that increases with the head moving toward the shoulder next to the affected eye sign of Bielschowsky, V-anisotropy and excyclotropia. The patients affected by acquired paresis and/or paralysis show vertical and torsional diplopia that increases when they look down, torticollis from inclining the head towards the opposed side of the affected eye, and lowering of the chin. A patient went to the doctor's because he presented with vertical and torsional diplopia of 13 years of progression. The ocular motility exam revealed orthotropia at primary position of look with hyperphoria at cover test in the left eye, 10 Dp inferior basis in bar prism test, excyclotropia 5, torticollis toward the right side and positive Bielschowsky index toward the left side. The diagnosis was acquired paresis of the left oblique superior muscle left of unspecified etiology. The treatment was over 4 mm retroinsertion of the superior rectum of the left eye plus one-fourth temporary displacement of the insertion, with the objective of eliminating the vertical and torsional diplopia and the anomalous position of the head

Secondary Superior Oblique Overaction after Inferior Oblique Muscle Myectomy in a Patient Misdiagnosed with Inferior Oblique Muscle Overaction

PURPOSE: To report a case of superior oblique muscle tenotomy in a patient with suspected bilateral inferior oblique muscle overaction. The patient showed secondary superior oblique muscle overaction and inferior oblique muscle underaction after inferior oblique muscle myectomy. CASE SUMMARY: The patient showed V-pattern exotropia with suspected bilateral inferior oblique muscle overaction. After bilateral lateral rectus muscle recession with bilateral inferior oblique muscle myectomy, the patient showed secondary esotropia and inferior oblique underaction. After the surgery, progressive secondary superior oblique muscle overaction continued and finally, a superior oblique muscle tenotomy was performed. After the superior oblique muscle tenotomy, the superior oblique muscle overaction was corrected but the inferior oblique muscle underaction continued. CONCLUSIONS: After an inferior oblique muscle myectomy, secondary superior oblique muscle overaction can develop. Thus, caution should be taken in diagnosing inferior oblique muscle overaction in patients who show minimally inferior oblique muscle overaction as well as the surgical methods chosen.

A Case of Congenital Absence of the Superior Oblique Muscle Treated With Anterior and Nasal Transposition of the Inferior Oblique Muscle

PURPOSE: To report a patient with absence of the superior oblique (SO) muscle of the left eye, who showed improvement after anterior and nasal transposition of the inferior oblique muscle for left hyperdeviation and right head tilt. CASE SUMMARY: A two-year-old boy presented with hypertropia of the left eye and right head tilt. Alternate prism-cover test in the primary position demonstrated 18 prism diopters (PD) of left hypertropia, which increased to 35 PD in the left head tilt position. A version test demonstrated overaction of the left inferior oblique muscle and underaction of the left superior oblique muscle. As an orbit CT scan showed absence of the SO muscle, the patient was diagnosed with congenital absence of SO and left anterior and nasal transposition of the inferior oblique muscle was performed. Three weeks after surgery, the patient presented with orthotropia at distant and near. The version test revealed normal oblique muscles. There was no vertical deviation shown on the Bielschowsky head tilt test. The abnormal head posturing was no longer observed. CONCLUSIONS: The authorsreport a patient manifesting abnormal head posture and hypertropia, diagnosed with absence of SO muscle, which was successfully corrected using anterior and nasal transposition of the inferior oblique muscle.

A Case of Acquired Brown Syndrome after Surgical Repair of a Medial Orbital Wall Fracture

A case of acquired Brown syndrome caused by surgical repair of medial orbital wall fracture is reported in the present paper. A 23-year-old man presented at the hospital with right periorbital trauma. Although the patient did not complain of any diplopia, the imaging study revealed a blow-out fracture of the medial orbital wall. Surgical repair with a calvarial bone autograft was performed at the department of plastic surgery. The patient was referred to the ophthalmologic department due to diplopia that newly developed after surgery. The prism cover test at distant fixation showed hypotropia of the right eye, which was 4 prism diopters (PD) in primary gaze, 20 PD in left gaze, while orthophoric in right gaze. Eye movement of the right eye was markedly limited on elevation in adduction with normal elevation in abduction with intorsion in the right eye present. Forced duction test of the right eye showed restricted elevation in adduction. Computerized tomography scan of the orbits showed the right superior oblique muscle was entrapped between the autografted bone fragment and posterior margin of the fracture. When repairing medial orbital wall fracture that causes Brown syndrome, surgeons should always be careful of entrapment of the superior oblique muscle if the implant is inserted without identifying the superior and posterior margin of the orbital fracture site.

The Effect of Inferior Oblique Muscle Surgery in Congenital Superior Oblique Palsy

PURPOSE: To compare the postoperative results of inferior oblique muscle operation in congenital superior oblique palsy (CSOP) according to the preoperative vertical deviation. METHODS: This study reviewed medical records of 26 patients who were diagnosed as CSOP with the largest vertical deviation at adducted position and incomitant vertical strabismus from May 2003 to April 2004 at hospital. The patients were divided into two groups, the group 1 (18 patients) shows less than 20 prism diopter (PD) vertical deviation at the primary position, the group 2 (10 patients) shows no less than 20 PD vertical deviation at the primary position preoperatively. We performed operation of the inferior oblique muscle (IOM) for both group. We evaluated the surgical effect at the primary position and both lateral gaze after 3 months. and performed reoperation as needed. RESULTS: Mean correction amount of vertical deviation at primary position of two groups were 11.6+/-2.7 PD in the group 1 and 7.4+/-3.5 PD in the group 2. Postoperative vertical deviation was decreased compared to preoperative value and it was statistically significant. But there were statistically significant differences in the corrected amount after inferior oblique muscle operation between two groups at all gazes. Surgical result of group 1 was successful (100%), but in group 2, all failed (100%) and needed reoperation. CONCLUSIONS: This study showed that corrected amount with IOM operation was smaller in CSOP with no less than 20 PD vertical deviation at primary position and incomitant vertical strabismus. It may be taken into consideration when operation for rectus and oblique musle were performed simultaneously in CSOP.

A Case of Congenital Absence of the Superior Oblique Muscle

PURPOSE: To report a patient with adsence of the superior oblique (SO) muscle of the right eye, who showed improvement after surgery for hyperdeviation and exotropia. METHODS: A four-year-old girl who presented with 14 PD exotropia, and 25 PD hypertropia of the right eye had a history of myectomy of the right inferior oblique (IO) muscle for bilateral SO palsy as a two-year-old. At the time of surgery, severely fibrotic pseudotendon of IO and Tenon's capsule attached to the insertional area of the inferior rectus muscle was found. IO was remyectomized with adhesiolysis. Lateral rectus and superior rectus (SR) muscles were recessed 6.5mm and 7mm, respectively. After exposure of SR, the absence of SO was found. MRI taken at postoperative one day showed definite SO absence. RESULTS: Three weeks after surgery, 4 PD of left hyperphoria at distant and 5 PD of left hyperphoria at near were observed. Right hyperdeviation was not detected. At postoperative 7 months, 4 PD of exophoria, 6 PD of right dissociated vertical deviation (DVD) and 10 PD of left DVD were seen at distant. A small left hyperdeviation was intermittently noted at upgaze and was cautiously followed. CONCLUSIONS: Absence of the superior oblique muscle is rare. However, such absence should be suspected when apparent superior oblique palsy accompanies with severe hyperdeviation and horizontal deviation. MRI or CT is helpful in the diagnosis of this condition and direct confirmation is needed.

Clinical Evaluation of Superior Oblique Muscle PalsyAssociated with Horizontal Deviation

PURPOSE: The purpose of this study is to provide useful clinical information for proper diagnosis of the superior oblique muscle palsy (SOP) associated with horizontal deviation. METHODS: The records of 186 patients with SOP treated surgically were reviewed. The patients who underwent surgery for horizontal deviation more than 10 PD were classified into SOP associated with horizontal deviation. RESULTS: Of 186 patients with SOP, 96 (51.6%) patients also showed horizontal deviation. In 59 patients (61.5%) of these 96 patients, chief complaint was horizontal deviation only and 24 patients (25.0%) knew their hyperdeviation. Compensatory head-tilt was shown in 52 patients (54.2%), however only 11 (11.5%) patients complained their head-tilt posture. Of 96 patients, 72 (82.3%) had horizontal deviation in the eye contralateral to the paretic eye and amblyopia occurred in the horizontally deviated eye. The frequency of exodeviation was 82.3 % and was more than that of esodeviation. The mean amount of hyperdeviation was 12.6 +/- 6.77 PD, and that of horizontal deviation was 22.9 +/- 8.13 PD in exodeviation and 22.5 +/- 9.17 PD in esodeviation, respectively ninety three patients (96.9%) showed positive Bielschowsky head-tilt test. All 83 patients who had fundus examination showed foveal extorsion. CONCLUSIONS: This study reveals that Bielschowsky head-tilt test and fundus examination for foveal extorsion are needed to diagnose SOP which is masked by prominent horizontal deviation.

A Case of Simultaneous Injury to Ipsilateral Superior Rectus and Superior Oblique Muscle

PURPOSE: Because the ipsilateral superior rectus (SR) and superior oblique (SO) muscles are innervated by two different nerves, it is very rare for these two muscles to be paralyzed while all other extraocular muscles function normally. The authors experienced a case where the patient had a loss of intorsion (action of both SR and SO muscles) and also loss of SO muscle's infraduction and adduction, and SR muscle's supraduction and abduction. The authors studied how such loss of function affects extraocular movement. METHODS: A 63-year-old male patient who had his SR and SO muscles severed by a saw was admitted to the hospital after getting rid of the two exposed muscle which were attached to the eyeball due to failure of reconstruction of two muscle. The patient was followed up for 8 months, and at the end of the follow-up period, the angle of deviation was measured while double Maddox test and fundus examination were also performed. RESULTS: At primary position there was extorsion of 7 degrees as well as esodeviation of 6 PD and hypodeviation of 6 PD on the left eye, and we hereby report the case.

The Effect of Modified Anterior Transposition of the Inferior Oblique Muscle for Hypertropia in Superior Oblique Muscle Palsy with Inferior Oblique Muscle Overaction

PURPOSE: The authers studied the effect of modified anterior transposition of the inferior oblique muscle for hypertropia in superior oblique muscle palsy combined inferior oblique muscle overaction. METHODS: We retrospectively analysed 19 cases of superor oblique palsy, which were treated by modified inferior oblique muscle anterior transposition from January 1999 to march 2001. Mean follow-up was 14.6 months. The medial portion of inferior oblique muscle was transpositioned to 1mm posterior position of the temporal insertion of inferior rectus muscle and lateral portion of inferior oblique muscle was moved 5mm on imaginary line, which is the line of between temporal insertion of inferior rectus and inferior insertion of lareral rectus muscle, to the direction of inferior insertion of lateral rectus muscle from temporal insertion of inferior rectus muscle, then backward 6mm from that point perpendicularly. RESULTS: The success rates in modified anterior transposition were 94% in under 20delta of hypertropia and 89.5% in over +3 of IOOA. CONCLUSIONS: Modified anterior transposition is an effective procedure of +3 to +4 inferior oblique muscle overaction and hypertropia in superior oblique muscle palsy as a primary surgery.

Surgical Correction of Exotropia due to Oculomotor Nerve Palsy

In third nerve palsy, the functions in the four of the six extraocular muscles are compromised and its treatment is the most difficult problem in the paralytic strabismus. In surgical method, large recession and resection of horizontal rectus muscles, lateral rectus muscle transposition to medial rectus muscle and superior oblique muscle transposition are used for strabismus surgery on oculomotor nerve palsied eye. We compared the results of two methods of surgical correction. In three eyes, lateral muscle transpositions to medial rectus muscle were performed. On the last follow up examination (men; 6.7 months), two eyes resulted in severe hypertropia and unacceptable ocular alignment and no improvement of limited adduction. In six eyes of whom superior oblique muscle transpositions were performed, all resulted in acceptable ocular alignment, no hypertropia, and the limitations of adduction were improved markedly. Therefore, in the treatment of third nerve palsy, sperior oblique muscle transposition is more effective than lareral rectus muscle transposition to medial rectus muscle.

Superior oblique lengthening procedure with silicone expander in rabbits

Using a rabbit model, we assessed the postoperative status and histopathologic findings of superior oblique tenotomy with silicone expander procedure. In the control group we marked and cut the superior oblique, and in the experimental group we inserted a silicone 240 retinal band 4 mm in length along the edges of incision. At the postoperative weeks 1,3,5 and 7, we randomly chose five rabbits and made a histopathologic examination after hematoxylin-eosin and Masson's trichrome stain. The distance between the incised edges was various in the control group, but constant in the experimental group. With time inflammation decreased and fibrosis of the superior oblique increased. Foreign body reaction occurred around the suture material in both groups., but not around the silicone expander. At 5 weeks atrophy of the superior oblique was observed in both groups.From the above results, we concluded that the superior oblique lengthening procedure using silicone expander is a useful surgical method for weakening the superior oblique muscle.

Strabismus Surgery on Congenital Oculomotor Nerve Palsied Eye

In congenital third nerve palsy, the function in four of the six extraocular muscles is compromised, and its treatment is the most difficult problem in paralytic strabismus. In general, either large recession and resection on horizontal rectus muscles or superior oblique muscle transposition is used for treatment. We compared the results of the two methods of surgical therapy. A Total of nine eyes in nine cases underwent surgical correction for ocular alignment in the primary position, In four eyes of four cases horizontal rectus muscle surgery was performed. In five eyes of five cases superior oblique muscle transposition was performed. Postoperatively, one of four cases who underwent horizontal rectus muscle surgery and four of five cases who underwent superior obique muscle transposition resulted in acceptable ocular alignment, in which the angle of deviation at the primary position was within 2 delta. Therefore, in the treatment of congenital third nerve palsy, superior oblique muscle transposition is more effective than horizontal rectus muscle surgery for the correction of ocular alignment.