RESUMEN
Objective To evaluate the antihyperglycemic potential of Tamarix aphylla (T. aphylla) leaves in STZ–NIC induced diabetes in Wister Albino rats. Methods Acute toxicity study was done to check the toxicity of T. aphylla (L. Karst) methanol extract. T. aphylla leaves extract was administered intraperitoneally (100 mg, 250 mg and 400 mg/kg body weight per day) to diabetic Wister rats for 21 days. The various parameters were studied including fasting blood glucose levels, haemoglobin and glycosylated haemoglobin. Results The treatment groups with the extract at three dose levels expressively abridged the intensities of blood glucose and Glycosylated Haemoglobin. The earlier detected reduced level of plasma haemoglobin of the diabetic rats was raised to near normalcy with treatment of extract. Conclusions The results of the current study confirm that the leaves extract of T. aphylla are nontoxic and have antidiabetic nature.
RESUMEN
Objective: To evaluate the antihyperglycemic potential of Tamarix aphylla (T. aphylla) leaves in STZ–NIC induced diabetes in Wister Albino rats. Methods: Acute toxicity study was done to check the toxicity of T. aphylla (L. Karst) methanol extract. T. aphylla leaves extract was administered intraperitoneally (100 mg, 250 mg and 400 mg/kg body weight per day) to diabetic Wister rats for 21 days. The various parameters were studied including fasting blood glucose levels, haemoglobin and glycosylated haemoglobin. Results: The treatment groups with the extract at three dose levels expressively abridged the intensities of blood glucose and Glycosylated Haemoglobin. The earlier detected reduced level of plasma haemoglobin of the diabetic rats was raised to near normalcy with treatment of extract. Conclusions: The results of the current study confirm that the leaves extract of T. aphylla are nontoxic and have antidiabetic nature.
RESUMEN
The main objective of this study was to generate perception in community regarding pollution of heavy metals contained in Aloe vera and Tamarix aphylla plants which have wide range of medicinal use but having toxic concentration of heavy metals. The plant samples were collected at three different areas referred as spots i.e. polluted (spot 1), less polluted (spot 2) and non- polluted (spot 3) from District Kohat, Khyber Pakhtunkhwa, Pakistan. In the present study, essential heavy metals such as Cobalt (Co), Nickel (Ni), Chromium (Cr), Copper (Cu), Iron (Fe) and Zinc (Zn) and non-essential heavy metals Cadmium (Cd), Lead (Pb) were analyzed in Aloe vera leaves and Tamarix aphylla by using Flame atomic absorption spectrophotometer. Heavy metals concentration in different spots were found to be in order as Spot 1> Spot 2>Spot 3 with the concentration range of found heavy metals., Cd 0.25-0.51 mg/kg, Pb BDL-15.23, Co 1.90-3.31mg/kg, Ni 2.98-4.01 mg/kg, Cr 4.86- 6.01 mg/kg, Cu 2.32-3.01 mg/kg, Fe 12.42-22.47 mg/kg, Zn 34.53-53.08 mg/kg for Aloe vera leaves and concentrations of the same heavy metals like Cd 0.13-0.31 mg/kg, Pb 1.00-18.01 mg/kg, Co 0.25-2.90 mg/kg , Ni 3.75-5.93 mg/kg , Cr 3.83-5.32 mg/kg , Cu 1.01-1.90 mg/kg, Fe 23.65-30.10 mg/kg , Zn 13.70-25.63 mg/kg were observed in the bark of Tamarix aphylla. Thus it was concluded from the present study that the samples collected from polluted area were found more contaminated with heavy metals as compared to less polluted and nonpolluted area.