RESUMEN
OBJECTIVE: To study the chemical constituents from the roots of Rubus parvifolius. METHODS: Various chromatographic techniques such as silica gel, Sephadex LH-20, and prep-HPLC column chromatography were used. RESULTS: Nineteen compounds, including 12 triterpenoids were isolated from the roots of Rubus parvifolius. Based on the analysis of their spectroscopic data, the structures of these 19 compounds were identified as p-hydroxybenzoic acid(1), 4-hydroxy-3, 5-dimethoxybenzoic acid(2), 3-methoxy-4-hydroxybenzoic acid(3), β-sitosterol(4), oleanolic acid(5), ursolic acid(6), 2-oxopomolic acid(7), pomolic acid(8), p-hydroxyphenylethyl alcohol(9), psiguanin A(10), 2α-hydroxyursolic acid(11), tormentic acid(12), 2α, 3α, 19α, 23-tetrahydroxyurs-12-en-28-oic acid(13), L-epicatechin(14), 2α, 3α, 19α, 24- tetrahydroxyolean-12-en-28-oic acid(15), 2α, 3α, 19α, 24-tetrahydroxyurs-12-en-28-oic acid(16), 2α, 3β, 19α-trihydroxyolean-12-en-23, 28-dioic acid(17), suavissimoside R1(18), and daucosterol(19), respectively. CONCLUSION: Compounds 1-3, 5, 7-10, 12, and 15-17 are isolated from the roots of R. parvifolius for the first time. Compounds 7 and 9 are isolated from the genus Rubus L. for the first time. Compounds 10 and 15-17 are isolated from the family Rosaceae for the first time.