RESUMEN
BACKGROUND: Viral warts are a common infectious disease and liquid nitrogen cryotherapy is one of the most common methods for treatment of these warts. Hand-foot viral warts frequently recur and reduce quality of life as well. OBJECTIVE: To find the ideal treatment interval between cryotherapy sessions that can influence not only the cure rate but also the recurrence rate for hand-foot viral warts. METHODS: A retrospective study was designed to compare a 2 week interval and a 3 week interval between cryotherapy sessions on hand-foot viral warts with respect to cure rate, recurrence rate, treatment number, duration of treatment, mean time to recurrence and adverse events. RESULTS: A total of 560 patients were enrolled. The overall cure rate was 75.7% and the recurrence rate was 19.6%. The mean time to recurrence was 7.8 months (range 1~26 months). For the 2-week and 3-week groups, cure rates were, respectively, 76.6% (196) and 75.0% (228); recurrence rates were 13.3% (26) and 25.0% (57). The mean time to recurrence was 9.8 months and 6.9 months, respectively. Adverse events were not statistically different. CONCLUSION: We suggested that 2-week cryotherapy is optimal not only because of the rapid cure but also because of the lower recurrence rate and similar adverse events.
Asunto(s)
Humanos , Enfermedades Transmisibles , Crioterapia , Nitrógeno , Calidad de Vida , Recurrencia , Estudios Retrospectivos , VerrugasRESUMEN
Until the recent development of the Q-switched lasers, it was not possible to remove tattoos without permanent scarring and pigmentary changes. Among the Q-switched lasers which was introduced under the concept of selective photothermolysis, Q-switched Nd-YAG laser has a longer wave(1064nm), deeper penetration, and lesser pigmentary change of skin than other type Q-switched laser. So, proved effectivity in removing pigmented lesion and tattoos without scarring and pigmentary changes. But repeated treatment is essential for a good result and than there is no agreement on the treatment interval in using Q-switched Nd-YAG laser. In this experiment, the author tattooed on the back skin of rabbits and treated them twice using Q-switched Nd-YAG laser in 5 groups of different treatment interval(1,2,4,6,8 weeks). The authors analysed the histology and final therapeutic results of the 5 groups to find a reasonable and shorter treatment interval by which we can obtain an effective therapeutic result without causing permanent tissue injury and change of the skin texture. The result shows that the 4 week treatment interval of Q-switched Nd-YAG laser for the tattoo removal in rabbits is the shortest term by which we can get effective therapeutic results without permanent scar and pigmentary changes.
Asunto(s)
Conejos , Cicatriz , Láseres de Estado Sólido , PielRESUMEN
Until the recent development of the Q-switched lasers, it was not possible to remove tattoos without permanent scarring and pigmentary changes. Among the Q-switched lasers which was introduced under the concept of selective photothermolysis, Q-switched Nd-YAG laser has a longer wave(1064nm), deeper penetration, and lesser pigmentary change of skin than other type Q-switched laser. So, proved effectivity in removing pigmented lesion and tattoos without scarring and pigmentary changes. But repeated treatment is essential for a good result and than there is no agreement on the treatment interval in using Q-switched Nd-YAG laser. In this experiment, the author tattooed on the back skin of rabbits and treated them twice using Q-switched Nd-YAG laser in 5 groups of different treatment interval(1,2,4,6,8 weeks). The authors analysed the histology and final therapeutic results of the 5 groups to find a reasonable and shorter treatment interval by which we can obtain an effective therapeutic result without causing permanent tissue injury and change of the skin texture. The result shows that the 4 week treatment interval of Q-switched Nd-YAG laser for the tattoo removal in rabbits is the shortest term by which we can get effective therapeutic results without permanent scar and pigmentary changes.