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1.
Artículo | IMSEAR | ID: sea-215915

RESUMEN

In this work the use of a mobile phone as a spectrophotometer using camera resolution by installing the software (application store AAP) on the phone (i Phone 6), which analyzes the colour images (RGB) in results with a colour length where it was possible to calculate the colour value of each image representing a specific concentration of the solution under study. A calibration curve with a range of (1 × 10-3-6.25 × 10-4) mmole.L-1 using optical image analysis with the concentration of the preparation of potassium permanganate (KMnO4). A calibration curve for statistical correlation range of 0.993 (R2) was found

2.
Artículo en Inglés | IMSEAR | ID: sea-163374

RESUMEN

Aims: UV Spectrophotometric Method for the Simultaneous Determination of Desloratidine and Pseudoephedrine HCl in combined Dosage form. Study Design: A simple, rapid and specific UV spectroscopic method with good sensitivity was developed and validated for the simultaneous determination of Desloratidine and Pseudoephedrine HCl in bulk and pharmaceutical dosage form. Place and Duration of Study: Department of pharmaceutical Analysis & Quality Assurance, School of Pharmacy, Anurag Group of Institutions, Venkatapur, R.R Dist, Andhra Pradesh, India during February 2013 and April 2013. Methodology: Vierodt’s (Simultaneous equation) method was performed for Estimation of Desloratidine and Pseudoephedrine HCl in Pharmaceutical dosage form. Results: In Ethanol the max of Desloratidine and Pseudoephedrine HCl was fixed as 240 and 258 nm respectively using a Shimadzu UV-Visible spectrophotometer. In this proposed method both drugs obeyed linearity within the concentration range of 5-30 g/ml and 80-800 g/ml for Desloratidine and Pseudoephedrine HCl respectively. The low RSD values indicate good precision and high recovery values indicate accuracy of the proposed method. The proposed method has been applied to the determination of drugs in commercial formulations. Assay results were in good agreement with label claim. The method was validated as per ICH guidliness. Conclusion: The developed method was simple, accurate, precise, specific, sensitive and reproducible which can be efficiently and easily applied to pharmaceutical dosage forms.

3.
Artículo en Inglés | IMSEAR | ID: sea-148278

RESUMEN

Objective:- Murraya koenigii commonly known as curry patta is used in the ancient medicine for curing different ailments. The aim of the present work is to estimate total phenolic content found in the leaves of Murraya koenigii. Method:- Total phenolic content of Murraya koenigii was assessed by Folin-Ciocalteu reagent by using gallic acid as calibration standard. Result:- The total phenolic content was measured by Folin-Ciocalteu was found to be 5.32. Conclusion:- From the findings it may be concluded that this drug may find use in diabetes and liver related problems.

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