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1.
Acta bioquím. clín. latinoam ; 54(1): 13-18, mar. 2020. graf, tab
Artículo en Español | LILACS | ID: biblio-1130574

RESUMEN

La deteccion de trastornos metabolicos minerales puede explicar diversas anomalias fisiologicas que exigen para su interpretacion la comparacion con valores de referencia validados. El objetivo de este trabajo fue la determinacion de valores de referencia en la poblacion infantil uruguaya, de los analitos sodio, potasio, calcio, magnesio, fosforo y urato relacionados con la creatinina en muestras de la segunda miccion de la manana en 470 escolares (240 ninas y 230 ninos) con edades comprendidas entre 7 y 12 anos. Las medianas obtenidas fueron: Na/Crea: 139 mmol/g, K/Crea: 78 mmol/g, Ca/Crea: 77 mg/g, Mg/Crea: 71 mg/g, P/Crea: 500 mg/g, Ur/Crea: 554 mg/g, Crea: 117 mg/dL. A excepcion de los cocientes Na/Crea y K/Crea se encontro una disminucion de la excrecion de estos analitos con la edad, independientemente del sexo. Los valores obtenidos resultaron ser analogos a los de otras poblaciones con tipo de alimentacion similar.


The detection of mineral metabolic disorders can explain several pathologies which require the comparison with reference values for their interpretation. The aim of this study was to determine the reference values of 470 Uruguayan school children with ages between 7 and 12 for sodium, potassium, calcium, magnesium, phosporous and urate and their relationship with creatinine in urine samples of the second urination of the morning. The median obtained were: Na/Crea: 139 mmol/g, K/Crea: 78 mmol/g, Ca/Crea: 77 mg/g, Mg/Crea: 71 mg/g, P/Crea: 500 mg/g, Ur/Crea: 554 mg/g, Crea: 117 mg/dL. A diminishment of excretion with the age was found, regardless the sex, except for Na/Crea and K/Crea. The values obtained were similar to those of others populations with a similar diet.


A detecção de distúrbios metabólicos minerais pode explicar várias anomalias fisiológicas, que exigem a comparação com valores de referência validados para serem interpretados. O objetivo deste estudo foi determinar valores de referência na população infantil uruguaia, dos analitos sódio, potássio, cálcio, magnésio, fósforo e urato relacionados com a creatinina em amostras da segunda micção da manhã em 470 alunos (240 meninas e 230 meninos) com idades entre 7 e 12 anos. As medianas obtidas foram: Na/Crea: 139 mmol/g, K/Crea: 78 mmol/g, Ca/Crea: 77 mg/g, Mg/Crea: 71 mg/g, P/Crea: 500 mg/g, Ur/Crea: 554 mg/g, Crea: 117 mg/dL. Com exceção dos quocientes Na/Crea e K/Crea, foi encontrada uma diminuição na excreção destes analitos com a idade independentemente do sexo. Os valores obtidos foram análogos aos de outras populações com um tipo similar de dieta.


Asunto(s)
Humanos , Masculino , Femenino , Niño , Valores de Referencia , Orina/química , Fósforo , Potasio , Sodio , Estudiantes , Ácido Úrico , Calcio , Creatinina , Dieta , Magnesio , Minerales
2.
Artículo | IMSEAR | ID: sea-186476

RESUMEN

Background: Worldwide urolithiasis is most common urological disease affecting both males and females. A kidney stone is a disease caused by some multi-factorial reasons like biochemical, environmental, epidemiological, genetic factors and especially diet will play an important role in expression of the tendency to stone formation. Aim: The present study was aimed to determine the composition of renal calculi by biochemical analysis. Materials and methods: A total of 43 study subjects of both sex groups were selected from the surgical urology unit of S.V.I.M.S Tirupati, and private Nursing homes in Tirupati, during the period of 16 months (May 2009 to September 2010). Nidumuru S, Kollur PB, Kollur BP, Kashinakunti SV, Pyadala N. Assessment of biochemical composition of renal calculi among patients visiting SVIMS, Tirupati. IAIM, 2016; 3(9): 103-107. Page 104 Results: A total of 50 renal stones were analyzed qualitatively, from 43 patients. In 43 patients, 39 were Males (90.69 %) and only 4 were Females (9.31%) and the incidence in male and female was in the ratio of 10:1. The highest number of cases, 40% of the total case is present in age group of 35-40 years followed by 32% in age group of 30-35 years. The Qualitative chemical analysis of renal stones revealed the presence of mixed stones with highest percent of CaOx (Calcium Oxalate) with CaP (Calcium Phosphate) stones for followed by uric acid. Conclusion: The present study concluded that knowing the biochemical composition of renal calculi is important during the treatment of renal stone disease and also giving advice to people for taking preventive measures for reducing the stone formation.

3.
Artículo en Inglés | IMSEAR | ID: sea-165940

RESUMEN

Background: Some studies highlighted that there was increase in the incidence of urinary tract problems related to frequent Urinary Tract Infections (UTIs) and crystalluria. This induces us to understand the prevalence of crystals in urine samples and its association with bacterial urinary tract infections. For determining the different types of urinary crystals, the role of microscopic examination for identification are routine and identical. Methods: The main objective of this study is to find out the predominant types of crystals in urine, age and sex incidence value, urine pH correlated with crystals and bacteriological examination of urine samples associated with UTIs. Results: Among 88 urine samples included, 49 (55.6%) were males and 39 (44.3%) were females of different age groups. By urine sediment analysis, among the normal crystals, calcium oxalate and amorphous urates were found predominant followed by cholesterol found among abnormal crystals. The results highlighted the presence of different types of crystals in the urine samples and strongly supported the pH ranges. The variations in the pH range from 3 to 7. The correlation of the results of crystal formation with bacterial culture showed predominance of Escherichia coli (19.3%) and further it gets proved with the theory and reference interpretation. Conclusion: By this study, the authors have a mystery whether the crystal formation leads to the bacterial infection or the infection leads to crystal formation. In the case of positive urine crystal analysis, the clinicians may consider the microbiological investigations to find out the real picture.

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