PROGRESS IN RESEARCH OF MICROORGANISMS OF NATURAL ENVIRONMENTS IN THE VIABLE BUT NON-CULTURABLE STATE / 微生物学通报

At the beginning of the 1980s, a concept of viable but non-culturable(VBNC) was suggested. VBNC is a survival strategy adopted by microorganisms when they are exposed to environmental stress. This article try to make a summary of research of the conditions of VBNC formation, recovery of culturability and methods of VBNC cells detection. In addition, introduces the first growth factor of microorganisms-Rpf.