RESUMEN
[Objective] To explore the levels of folic acid(FA), vitamin(Vit) Bl2 and homocysteine(Hcy) of gestational diabetes mel itus(GDM) patients and the relation among them. [Method] Select 40 GDM cases from our hospital diagnosed with oral glucose tolerance test(0GTT) and 40 healthy pregnant women in the same period, take circulation enzymic method to test Hcy concentration, and take chemiluminescence to measure FA and VitBl2. [Result] GDM patients’Hcy level is in negative relation with VitBl2 and FA levels. Comparing GDM patients’serum Hcy,VitBl2 and FA with normal pregnant group,Hcy level is raised much(P<0.01), FA and VitBl2 are reduced markedly(P<0.01). In later period of GDM pregnancy, they have high Hcy, lack of FA and Vit-Bl2; the pregnancy hypertension shal strengthen the intake of VitBl2 and FA, as wel as have periodical supervision, to reduce Hcy level and decrease the side effects on fetus and injury to pregnant women’s great vessels and micro-vessels.
RESUMEN
Objective To observe the application effect of Yunnan baiyao powder and alcohol with VitB12 on exosmosis of vincristin. Methods The 40 patients with exosmosis of vincristin were randomly divided into the treatment group(22 cases)and the control group( 18 cases).The treatment group was given the Yunnan baiyao powder and alcohol with VitB12,the control group was given magnesium sulfate for hydropathic compress.The effective rate and red swelling and ulcer of the skin in the two groups were evaluated. Results The effective rate of the treatment group was higher than that of the control group,red swelling and the diameter of the ulcer of the skin on the fifth and seventh day were shorter than the control group. Conclusions The Yunnan baiyao powder and alcohol with VitB12 are effective in treatment of the exosmosis induced by vincristin.
RESUMEN
Objective To explore the relationship between plasma homocysteine(Hcy),folic acid,VB12 level and deep venous thrombosis(DVT).Method With case-control study design,fifty DVT patients were included in this study as case group,and 50 healthy subjects selected from the same area as control group.Epidemiological survey were made,and 4ml fasting venous blood was collected for all subjects.Radio-immunoassay and fluorescence polarization immunoassay(FPIA) were used to measure blood serum folic acid,VB12 and plasma Hcy levels respectively.The correlation between Hcy level and DVT was analyzed.Results Plasma Hcy level of subjects in case group was higher than that in control group,There was significant difference of HHcy and low serum folic acid between case and control,and the OR(95%CI) was 3.74(1.21-11.59)and 0.17(0.05-0.53) respectively.There existed correlation among Hcy level,folic acid and VB12 levels.Partial correlation analysis showed the same results between Hcy level and folic acid level,VB12 level and folic acid level,while there existed negative correlation between Hcy level and VB12 level.Conclusion HHcy and low blood folic acid level increased DVT risk.Low blood levels of folic acid and VB12 increase the risk of HHcy.