Variables in the Whole Cow's Milk Intake, that Impact upon the Iron Status in Early Childhood / 대한소아혈액종양학회지

BACKGROUND: It was recognized that the intake of the whole cow's milk(WCM) early (before 1 year old of age) and large amount in early childhood is related to the iron deficiency, sometimes the iron deficiency anemia in advanced state. To verify the relationship between the variables in the WCM intake and the iron status, we carried out this study. METHODS: Thirty subjects(1 year to 3 years old of age) were classified as a WCM large intake group and a WCM small intake group. The relationship between the WCM commencing age and the iron status(serum ferritin, transferrin saturation and hemoglobin) in the WCM large intake group was evaluated and analyzed by the linear regression. Futhermore, the relationship between the value of WCM intake amountxduration/10 and the iron status(serum ferritin, transferrin saturation and hemoglobin) in the WCM large and small intake groups was evaluated and analyzed by the linear regression. RESULTS: As the WCM commencing age was earlier, the values of serum ferritin, transferrin saturation and hemoglobin decreased significantly(P0.1). CONCLUSION: The variables in the intake of WCM influence upon the iron status in early childhood. The early commencing of the WCM(before 1 year old of age) is the worst variable that influences adversely upon the iron status in early childhood. The amount of WCM intake and the duration influence upon the storage iron(serum ferritin and transferrin saturation), but not hemoglobin. In this regard, it is necessary to inform the parents of the correct WCM intake ways to avoid the irreversible recognition impairment and behavioral change.

The Impact of Prolonged Breast Milk Feeding and Large Amount of Whole Cow' s Milk Intake on Iron Status in Early Childhood

PURPOSE: The Large amounts of whole cow' s milk intake, just followed by prolonged breast milk feeding may induce a severe deficit of iron. We performed this study to investigate the severity of iron deficiency in these subjects. METHODS: Seventy-one subjects (12 to 48 months of age) were classified according to history of prolonged breast milk feeding and intake of large amounts of whole cow' s milk. Prolonged breast milk feeding and large amounts cow' s milk intake subjects were assigned as group A (n=15), the large amounts of cow's milk intake subjects as group B (n=15), the prolonged breast milk feeding subjects as group C (n=24) and the normal control subjects as Group D (n=17). The hematologic and iron status were evaluated and compared between each group. RESULTS: Although the mean of group A was lower than the mean of group B and C, the level of hemoglobin of group A was significantly lower than group D (P<0.01). The level of the ferritin of group A was significantly lower than group B, C (P<0.05, respectively) and group D (P<0.01). Of the 15 study subjects of group A, 14 (93.3%) had microcytic hypochromic anemia and 7 (46.7%) revealed that serum ferritin levels were at 1.0ng/dL, indicating severe deficit of storage iron. CONCLUSION: The intake of large amounts of whole cow' s milk, just followed by prolonged breast milk feeding induced iron deficiency anemia and a severe deficit of storage iron. It is necessary to inform parents to avoid irreversible recognition impairment and behavioral change.

Serum Concentration of Major Minerals, Trace Elements, Lipids and Fatty Acids Composition Related to Whole Cow's Milk Feeding in Infancy & Young Childhood / 대한지역사회영양학회지

This study was conducted to determine the effect of large amounts of whole cow's milk intake on serum levels of minerals and lipids. Subjects were normal infants who were brought to the pediatric hospital for vaccination at the age of 7-26 months after birth, living in Eumsung-Choongbuk area. The serum concentrations of the imnerals(calcium, phosphorus, magnesium, iron, zinc and copper), lipids and fatty acids composition were analyzed in 38 infants which consumed large amount of whole cow's milk(over 700ml/day). The results obtained are summarized as follows : 1) The mean levels of calcium, phosphorus and magnesium in the serum of the total subjects were 7.56+/-0.51mg/dl, 11.12+/-0.72mg/dl and 1.62+/-0.13mg/dl respectively. The serum concentrations of iron, zinc and copper in total subjects averaged 72.42+/-1.62 microgram/dl, 76.29+/-3. 62 microgram/dl and 86.44+/-2.98 microgram/dl respectively. 2) The mean serum concentrations of triglyceride, total cholesterol, HDL and LDL in the total number of subjects were 96.84+/-9.22mg/dl, 133.45+/-6.30mg/dl, 32.79+/-1.77mg/dl and 81.29+/-4.81mg/dl respectively. 3) The average percentages of SFA, MUFA and PUFA inth total serum fatty acids were 38.98+/-2.42%, 25.82+/-0.98% and 37.30+/-1.09% respectively and the mean omega6/omega3 fatty acids ratio was 13.48. In general, the levels of serum minerals and omega3 fatty acid composition in the subjects of this study, who were whole cow's milk fed infants were lower than those reported in breast milk or formula fed infants. Therefore, the intake of large amount of whole cow's milk in the weani ng period should be controlled and adequate for the infant's nutritional status.

A Survey about the Usage of Whole Cow's Milk and Commercial Baby Food in Children

PURPOSE: The appropriate age and amount that whole cow's milk and commercial baby food can be introduced safely into the infant diet are unknown and remains an area of controversy. Early feeding of excessive amount of whole cow's milk has been associated with iron deficiency anemia and nutritional deficiency. We studied the present status and problems on the feedig of whole cow's milk and commercial baby food in children. METHODS: This survey was done through questionnaire to the 541 out patients who visited Seoul, Chun An and Eum Sung Soon Chun Hyang University Hospitals during the period from Jun. 1994 to Fab. 1995. RESULTS: 1) Feeding patterns according to age of children: Infants were fed prepared milk(63.6%), human milk(16.2%), whole cow's milk(8.1%), commercial baby food(7.1%) and rice(5.0%) in the order of frequency. Children between 1 and 2 years of age were fed rice(37.1%), whole cow's milk (34.3%), prepared milk(17.1%), commercial baby food(7.4%) and human milk(4.0%) in the order of frequency. 2) Whole cow's milk feeding was started at 3 to 6 months of age in 11.5%, at 7 to 12 months of age in 59.6% and after 12months of age in 28.9%. 3) The daily feeding amounts of whole cow's milk was less than 500 ml in 48.2%, 500 to 999 ml in 36.2%, and more than 1000 ml in 15.6%. Suprisingly 49.7% of them were fed more than 500 ml a day. 4) About iron content in whole cow's milk, only 25.9% of mothers gave the correct answer. 5) 62.5% of mothers considered that whole cow's milk was the best food in infant period. 6) Only 19.1% of subjects used commercial baby food properly in method and amount. CONCLUSIONS: Whole cow's milk was introduced during early months of life and fed in excessive amount. There was a lack of maternal knowledge about iron content in whole cow's milk. The improper use of commercial baby food produced the numerous nutritional problems. Thus, we need education about whole cow's milk and commercial baby food to mothers.

The impact of large amount whole cow's milk intake on iron status in early childhood

To determine the impact of intake large amount whole cow's milk (WCM) on iron status during early childhood (18~36 months), selected indices of complete blood count(CBC) and iron status were compared between the WCM large amount intake group (n=20)and small amount intake group (n=20). WCM large amount intake children's mean hemoglobin and mean hematocrit were 9.6+/-1.7 g/dL and 30.8+/-4.5% respectively. These range of peripheral blood with other indices of CBC disclosed the hypochromic microcytic anemia. WCM large amount intake children's some indices of CBC-hemoglobin, hematocrit, MCV, MCH-were significantly lower than those of small amount intake children (P<0.01). WCM large amount intake children had significantly lower mean iron, transferrin saturation and ferritin (P<0.01) and greater mean total iron binding capacity (P<0.05) than did small amount intake children. It is concluded that intake large amount of WCM for long duration impacts on the iron status of 18~36 months old children disadvantageously. It should be avoided for the protection of irreversible recognitive impairment and behavioral change.

Factors which affect the serum ferritin in whole cow's milk related iron deficiency anemia children

No abstract available.