RESUMEN
OBJECTIVE： To provide reference for the improvement of drug information traceability system in China. METHODS： Using “drug information traceability”“drug traceability”“electronic drug supervision” as keywords， related literatures，relevant laws and regulations about drug information traceability were retrieved from PubMed， CNKI， Wanfang database， VIP， Drug Supervision Department or Health Administration websites of USA， EU and China from Jan. 2014 to Apr. 2019. Compared with USA and EU， the problems of drug information traceability system in China were analyzed to put forward the countermeasures and suggestions. RESULTS & CONCLUSIONS：A total of 31 literatures were included. The drug information traceability system was established in USA， EU and China. USA and EU have the advantages of coding to be in line with international standards， making full use of third-party platforms to avoid forming monopoly， etc. Drug information traceability system was still in a crucial stage of improvement in China. There were still many problems， such as more specific operating standards and guidelines are needed， too many supply chain participants， uneven information level， drug information traceability system independent of the transaction， reimbursement and other information systems， and insufficient coordination. It is suggested to improve the relevant laws and regulations on drug information traceability system by drug supervision department as soon as possible， and give full play to the role of third-party platform， and establish drug information traceability platform based on drug trading platform so as to ensure the system to play an important role in deepening the reform of medical and health system， ensuring the supply of shortage drugs， promoting rational drug use and comprehensive supervision.