RESUMEN
OBJECTIVE:To establish TLC scanner method for the determination of stachydrine hydrochloride in xue?niaokang granule.METHODS:Silica gel G thin layer plate was adopted in the determination with n-butanol-hydrochloric acid-ethyl acetate(8∶3∶1)used as developer and thin potassium heptaiodobismuthate test solution used as color-developing agent,the detection wavelength was515nm,the reference wavelength was700nm and the slit size was6.00mm?0.45mm.RESULTS:Good linear correlation with the peak area score of spots achieved when the concentration range of stachydrine hydrochloride was within5.06?g~25.32?g(r=0.9978),the average recovery was96.67%(RSD=2.01%).CONCLUSION:The method was accurate,simple,reliable,sensitive and reproducible,and it can be used for the determination of xueniaokang granule and its quality control.