Alcaptonuria: evolución y curso de la enfermedad hacia artropatía ocronótica. Serie de casos manejados con reemplazo articular / Alkaptonuria: evolution and course of the disease towards ochronotic arthropathy. Series of cases managed with joint replacement

Resumen: Introducción: la alcaptonuria es una enfermedad metabólica inusual, de herencia autosómica recesiva dada por la deficiencia de la oxidasa de HGA. Clásicamente descrita y diagnosticada sobre la tercera a cuarta década de la vida, la cual tiene afectación en ambos sexos, su impresión diagnóstica es clínica, basándose en la coloración azul/negro de las conjuntivas; sin embargo, se confirma mediante el análisis específico de la enzima en la orina, actualmente no existe un tratamiento definitivo, sólo alternativas en cuanto a lo paliativo y sintomático. Material y métodos: estudio descriptivo, observacional, de tipo serie de casos, como objetivo primario se describe la progresión de la enfermedad y su compromiso en el sistema musculoesquelético. Resultados: se presentan dos casos clínicos en mujer y hombre, los cuales ilustran: variedad clínica, avance progresivo y las alteraciones que puede generar en el sistema musculoesquelético. Conclusiones: la alcaptonuria es una enfermedad rara, la cual conlleva una artropatía secundaria severa, sin un tratamiento definitivo dirigido a tratar los síntomas, incluso en sus estadios finales los reemplazos articulares son una opción para proporcionar manejo del dolor obteniendo resultados satisfactorios.

Abstract: Introduction: alkaptonuria is a very rare metabolic disease with autosomal recessive inheritance due to HGA oxidase deficiency. Classically described and diagnosed in the third to fourth decade of life, affecting both men and women; Its diagnostic impression is clinical based on the blue/black coloration of the conjunctivae, however it is confirmed by the specific analysis of the enzyme in the urine, to date there is no cure and its treatment is palliative and symptomatic. Material and methods: descriptive, observational, case series study, the primary objective of which is to describe the progression of the disease and its involvement in the musculoskeletal system. Results: two clinical cases are presented in women and men in which the broad clinic is illustrated, its progressive advance and the different alterations that it can generate in the musculoskeletal system. Conclusions: alkaptonuria is a rare disease which leads to a severe secondary arthropathy, currently without a specific management which is based on treating the symptoms, in its final stages joint replacements are a management option with satisfactory results for the relief of pain.

Hemiartroplastía por interposición utilizando el extensor hallucis brevis para el tratamiento de hallux rigidus con involucro unicompartimental lateral: reporte de un caso / Interposition hemiarthroplasty using extensor hallucis brevis for the treatment of hallux rigidus with lateral unicompartmental involvement: a case report

Resumen: Hallux rigidus es la patología degenerativa de la articulación metatarsofalángica del hallux. Esta patología provoca dolor y disminución en el movimiento. Existen múltiples tratamientos quirúrgicos para esta patología, todas con sus respectivas indicaciones. Presentamos el caso de un paciente de 54 años de edad con el diagnóstico de hallux rigidus quien tenía afectación únicamente del aspecto lateral de la cabeza del metatarsiano. Este paciente fue tratado con un procedimiento quirúrgico novedoso, se realizó una hemiartroplastía de interposición utilizando el extensor hallucis brevis asociado a una queilectomía y exostectomía. El paciente tuvo una favorable evolución clínica con mejoría evidenciado por escalas clínicas, con resolución de la sintomatología y sin complicaciones. La hemiartroplastía de interposición utilizando el extensor hallucis brevis es un tratamiento exitoso de preservación articular y del movimiento para el hallux rigidus en pacientes jóvenes en los que hay afectación unicompartimental lateral de la cabeza metatarsiana, en quienes es importante preservar el movimiento.

Abstract: Hallux rigidus is the degenerative pathology of the metatarsophalangeal joint of the hallux. This pathology causes pain and decreased movement. There are multiple surgical treatments for this pathology, all with their respective indications. We present the case of a 54-year-old patient diagnosed with hallux rigidus who had only the lateral aspect of the metatarsal head affected. This patient was treated with a novel surgical procedure, performing an interposition hemiarthroplasty using the hallucis brevis extender associated with a cheilectomy and exostectomy. The patient had a favorable clinical evolution with improvement evidenced by clinical scales, with resolution of the symptoms and without complications. Interposition hemiarthroplasty using the extensor hallucis brevis is a successful joint and movement preservation treatment for hallux rigidus in young patients with lateral unicompartmental involvement of the metatarsal head, in whom it is important to preserve movement.

Factores relacionados con osteoartritis en trabajadores informales del centro de Medellín, Colombia / Related factors with Osteoarthritis in informal workers in Medellin downtown, Colombia

Resumen Introducción: Se hace una correlación entre la osteoatrosis y las condiciones laborales, hábitos y estilos de vida de los trabajadores informales del centro de Medellín, Colombia. Objetivo: Identificar la relación de la osteoartritis y la prevalencia de enfermedades crónicas y degenerativas con las condiciones sociodemográficas, laborales, hábitos y estilos de vida en un grupo de trabajadores informales de Medellín, Colombia. Materiales y métodos: Estudio transversal, con fuente primaria de información de 686 trabajadores informales. Se realizó una encuesta asistida, previa toma de consentimiento. Se seleccionaron 289 trabajadores con diagnóstico de enfermedad crónica o degenerativa, ≥18 años, con ≥5 años en su oficio. Se realizaron análisis exploratorios y de asociación con prueba Chi2, y cálculo de RP con IC del 95%. Resultados: el 79,9% de la población padecía alguna enfermedad crónica. El 3,46% presentaba diagnóstico de osteoartritis, siendo significativamente mayor (p<0,05) en quienes tenían entre 21 y 30 años en su oficio (RP=5,62. IC:1,20;26,34). También fue mayor la prevalencia de osteoartritis en; >45 años (RP=2,26), mujeres (RP:4,44), trabajadores sedentarios (RP=1,71), obesos (RP=3,40), así como en quienes habían sido obreros (RP=1,30), en aquellos que tenían puestos de venta semiestacionaria (RP=2,21), vendían productos de cosecha y perecederos (RP=1,78), en quienes trabajaban >8 horas diarias (RP:2,77), ≤5días a la semana (RP=3,10), no tenían espacio suficiente para moverse (RP=2,08), y en quienes tenían posturas o movimientos forzados (RP=2,72). Conclusión: En la población de vendedores informales del centro de Medellín, los factores sociodemográficos, laborales, hábitos y estilos de vida modificables se relacionan con una mayor prevalencia de osteoartritis.

Abstract Introduction: A correlation is made regarding osteoarthrosis and working conditions and lifestyles of informal workers in Medellin downtown. Objective: To identify the prevalence of chronic and degenerative diseases, and the relationship of osteoarthritis with sociodemographic and work conditions, habits and lifestyles, in a group of informal workers from Medellín, Colombia. Materials and methods: Cross-sectional study, with a primary source of information, with 686 workers. An assisted survey was applied, after obtaining consent. 289 workers with a diagnosis of chronic or degenerative disease, ≥18 years old, with ≥5 years in their profession were included. Exploratory and association analysis with Chi2 test, and calculation of PR with 95% CI. Results: 79.9% of them suffered from a chronic disease. 3.46% had a diagnosis of osteoarthrosis, being significantly higher (p <0.05) in those who had spent between 21 and 30 years performing their profession (PR=5,62.CI:1,20;26,34). The prevalence of osteoarthrosis was also higher in; >45 years (PR=2.26), women (PR=4,44), sedentary workers (PR=1,71), obese (PR=3,40), as well as those who had been brick-layers (PR=1,30), in those who had semi-stationary sales positions (PR=2,21), they sold harvest and perishable products (PR=1,78), in those who worked> 8 hours a day (PR:2,77), ≤ 5 days a week (PR=3,10), they did not have enough space to move (PR = 2.08), and in those who had forced postures or movements (PR=2,72). Conclusion: sociodemographic and work factors, habits and modifiable lifestyles are related to a higher prevalence of osteoarthrosis in this working population.

Medial Knee Arthrosis: A Pathology with a Progressive Evolution / Artrose medial do joelho: Uma patologia de evolução progressiva

Abstract Medial arthrosis of the knee is an evolutionary pathology that occurs due to progressive muscle imbalance. The muscles of the knee region have a large imbalance caused by the difference of power and lever arm. With the progression of life, this imbalance manifests itself more importantly, especially due to the loss of muscle strength due to aging. Pathological postures begin to occur and determine areas of support and pressure harmful to the joint. Meniscal injury is typical in the evolution of this pathology, as well as cartilage injury. The recognition of this pathology enables good results with less aggressive treatments, such as correction of muscle imbalance and consequent reeducation of joint support. Economic and partial meniscectomy brings good results in the early stages of the degenerative process. Progressive evolution leads to knee degeneration and the consequent need for broader surgeries.

Resumo A artrose medial do joelho é uma patologia evolutiva que ocorre em decorrência de desequilíbrio muscular progressivo. Os músculos da região do joelho têm um grande desequilíbrio, provocado pela diferença de potência e braço de alavanca. Com a progressão da vida, este desequilíbrio se manifesta de forma mais importante, especialmente em decorrência da perda de força muscular em função do envelhecimento. Posturas patológicas passam a ocorrer e determinar zonas de apoio e pressão lesivas para a articulação. A lesão meniscal é típica na evolução desta patologia, assim como a lesão da cartilagem. O reconhecimento desta patologia possibilita resultados bons com tratamentos menos agressivos, como a correção do desequilíbrio muscular e consequente reeducação do apoio da articulação. A meniscectomia econômica e parcial traz bons resultados nas fases iniciais do processo degenerativo. A evolução progressiva leva à degeneração do joelho e à consequente necessidade de cirurgias mais amplas.

Unicompartimental knee arthroplasty - 15 years follow up / Artroplastia unicompartimental do joelho - 15 anos de seguimento

ABSTRACT Objective: To evaluate clinically and radiologically the long-term follow-up of patients with anteromedial osteoarthritis who underwent unicompartmental knee arthroplasty surgery. Methods: This study included 36 patients who underwent unicompartmental knee arthroplasty surgery for medial compartmental osteoarthritis with a minimum of 15-year post-operative follow-up. All surgeries were performed by a single surgeon (G.L.C) using the Miller-Galante unicompartmental knee implant. Patients were analyzed regarding their clinical functional and implant radiographic conditions. Results: From the 46 patients who could have completed 15 years of follow-up, three required revision surgery with conversion to total knee arthroplasty (6.5%), 36 completed the 15-year follow-up period, and the others were lost to follow-up for reasons not related to unicompartmental arthroplasty. Conclusion: In these 36 patients, the result was satisfactory after follow-up, with complaints and sign of progression of osteoarthritis in some cases. Level of Evidence IV, Case series.

RESUMO Objetivo: Avaliar clínica e radiologicamente o acompanhamento a longo prazo de pacientes com osteoartrite anteromedial do joelho que passaram por cirurgia de artroplastia total do joelho. Métodos: Este estudo incluiu 36 pacientes que se submeteram à artroplastia unicompartimental do joelho por lesão do compartimento medial provocada por artrose com, no mínimo, 15 anos de acompanhamento pós-operatório. Todas as cirurgias foram realizadas pelo mesmo cirurgião (G.L.C.) utilizando uma prótese unicompartimental tipo Miller-Galante. Os pacientes foram analisados quanto as suas condições clínicas e condições radiográficas do implante. Resultados: Dos 46 pacientes que poderiam ter concluído 15 anos de acompanhamento, 3 necessitaram de revisão com artroplastia total (6,5%); 36 concluíram os 15 anos de acompanhamento, e o restante abandonou o acompanhamento por razões independentes da artroplastia unicompartimental. Conclusão: Nestes 36 pacientes, o resultado foi satisfatório após o acompanhamento, com queixas e sinais de progressão da artrose em alguns casos. Nível de Evidência IV, Série de casos.

Shoulder Arthroplasty: Tenotomy of the Subscapularis Tendon versus the Lesser Tuberosity Osteotomy / Artroplastia de ombro: tenotomia do subescapular versus osteotomia do tubérculo menor

Abstract Objective To evaluate and compare subscapular muscle function among patients undergoing subscapular tenotomy (Group A) and lesser tuberosity osteotomy (Group B), in patients treated with total and partial anatomic shoulder arthroplasty for primary osteoarthrosis. Methods Retrospective study of patients with primary glenohumeral osteoarthrosis surgically undergoing total or partial anatomic shoulder prosthesis implant, evaluated by clinical examination, imaging exams, analogue pain scale and Constant and Murley functional score. A total of 28 patients were evaluated, totalizing a sample of 32 operated shoulders. The minimum follow-up was of 12 months (mean 47.45 months). Results Among patients submitted to subscapularis tendon tenotomy, 10 had an ultrasound with total rupture of its thickness (56%). All of the patients of the group B showed lesser tuberosity healing. There was no difference between groups comparing strength evaluated by Belly press and Bear hug tests as well as clinical outcome, through the Constant and Murley score. Conclusions We did not find differences between Groups A and B evidenciated by comparing strength in the Lift-off test, in the Belly press and Bear hug tests and through he Constant and Murley score.

Resumo Objetivo Avaliar e comparar a função do músculo subescapular entre os grupos submetidos a tenotomia do subescapular (Grupo A) e osteotomia do tubérculo menor (Grupo B), em pacientes tratados por artroplastia anatômica total e parcial de ombros apresentando osteoartrose primária. Métodos Estudo retrospectivo de pacientes portadores de osteoartrose primária glenoumeral tratados cirurgicamente com prótese anatômica total ou parcial de ombro, avaliados por exame clínico, exames de imagens, escala visual analógica de dor e escore funcional de Constant e Murley. Foram avaliados 28 pacientes, totalizando uma amostra de 32 ombros operados. O seguimento mínimo foi de 12 meses (média 47,45 meses). Resultados Nos pacientes submetidos à tenotomia do tendão subescapular, dez obtiveram resultado ultrassonográfico com ruptura de sua espessura total (56%). A consolidação ocorreu em todos pacientes submetidos a osteotomia do tubérculo menor. Não houve diferença entre os grupos na comparação do teste Lift Off, da força nos testes Belly Press e Bear hug, e no escore de Constant e Murley. Conclusões Não encontramos diferença entre os grupos A e B na comparação do teste Lift Off, da força nos testes Belly Press e Bear hug, e no escore de Constant e Murley.

Review of basic trends in cryotherapy applications for horse injuries / Revisão das tendências básicas em aplicações de crioterapia em lesões em cavalos

While solving the problem of sport horses' pathologies it is important to choose safe and environmentally friendly methods, including cryotherapy, which is the topic of our research. The use of cryotherapy is a promising means of treatment of primary injury, rehabilitation in post-traumatic conditions and in chronic injuries. Prospects of cryotherapy applications in horse breeding, in particular in sports and prize areas, were researched. It was found out that modern sport horses training and their involvement in competitions is associated with serious stress on their locomotor system and maximum mobilization of all body systems, which overstrains certain muscle groups, determines increased probability and severity of injury incidence, reduction of sport longevity and worse performance in competitions.(AU)

Na resolução do problema das patologias dos cavalos esportivos é importante escolher métodos seguros e ecológicos, incluindo a crioterapia, que é o tópico desta pesquisa. O uso da crioterapia é um meio promissor no tratamento de lesões primárias, reabilitação em condições pós-traumáticas e lesões crônicas. Foram pesquisadas as perspectivas de aplicações da crioterapia na criação de cavalos, particularmente em esportes e prêmios. Verificou-se que o treinamento moderno de cavalos esportivos e seu envolvimento em competições está associado com severo estresse sobre seu sistema locomotor e mobilização máxima de todos os sistemas corporais, que sobrecarregam certos grupos musculares, determinam maior probabilidade e severidade da incidência de lesões, e reduzem a longevidade no esporte e pior desempenho em competições.(AU)

Reverse shoulder arthroplasty: Functional results in rotator cuff arthropathy / Artroplastia reversa de ombro: Resultados funcionais na artropatia do manguito

Abstract Objective To evaluate the functional results of patients submitted to reverse shoulder arthroplasty for the treatment of rotator cuff arthropathy refractory to conservative treatment. Methods A retrospective study of 20 patients (21 shoulders), 17 women (81%) and 3 men (19%), underwent a reverse shoulder arthroplasty between October 2012 and September 2017, for a rotator cuff arthropathy treatment, operated by a single surgeon in a single center. The patients were assessed using the Disabilities of the Arm, Shoulder and Hand (DASH) score, the Short-Form (36) Health Survey (SF-36), the visual analogue scale (VAS) of pain rating, and the University of California - Los Angeles (UCLA) score. The mean age at surgery was of 66 years old (range: 55 to 83 years old). The duration of symptoms before surgery was of ∼ 2.5 years (range: 12 months to 6 years). The mean follow-up was of 42.4 months (range: 19 to 56.7 months). Results The mean postoperative scores were 18.2 points in DASH; 2 points in EVA, of which 16 (77%) corresponded to mild pain, 4 (18%) to moderate pain, and 1 (5%) to severe pain; 29 points in UCLA, of which 6 patients presented a regular result (28%), 10 patients a good result (48%), and 5 patients an excellent result (24%); and 63 points in the SF-36. The complications were four cases of notching, one case of acromial fracture due to stress, and one case of postoperative infection. Conclusions Reverse arthroplasty of the shoulder presents good functional results in the evaluated scores, providing a significant improvement in the quality of life of the patients.

Resumo Objetivo Avaliar os resultados funcionais dos pacientes submetidos a artroplastia reversa de ombro, para tratamento da artropatia do manguito refratária a tratamento conservador. Métodos Estudo retrospectivo de 20 pacientes (21 ombros), 17 mulheres (81%) e 3 homens (19%), submetidos a artroplastia reversa de ombro no período de outubro de 2012 a setembro de 2017, para tratamento de artropatia de manguito rotador, operados por um único cirurgião em um único centro. Os pacientes foram avaliados pelo escore de disfunções do braço, ombro e mão (DASH, na sigla em inglês), pelo questionário genérico de avaliação de qualidade de vida SF-36 (SF-36), pela escala visual analógica de dor (EVA) e pelo escore da Universidade de Los Angeles - Califórnia (UCLA, na sigla em inglês). A média de idade na cirurgia foi de 66 anos (variação de 55 a 83 anos). O tempo de sintomas antes da realização da cirurgia foi de ∼ 2,5 anos (variação de 12 meses a 6 anos). O seguimento médio foi de 42,4 meses (variação de 19 a 56,7 meses). Resultados A média dos escores pós-operatórios foi de 18,2 pontos no DASH; de 2 pontos na EVA, sendo 16 (77%) de dores leves, 4 (18%) de dores moderadas e 1 (5%) de dor intensa; de 29 pontos no UCLA, sendo 6 pacientes com resultado regular (28%), 10 pacientes com resultado bom (48%), e 5 pacientes com resultado excelente (24%); e de 63 pontos no SF-36. Tivemos como complicações quatro casos de notching, um caso de fratura de acrômio por estresse, e um caso de infecção pós-operatória. Conclusões A artroplastia reversa do ombro apresenta bons resultados funcionais nos escores avaliados, propiciando melhora significativa na qualidade de vida dos pacientes.

Panorama of Infiltration for Painful Shoulder Among Shoulder Specialists / Panorama da infiltração para ombro doloroso entre especialistas em ombro

Abstract Objective To assess how shoulder specialists have used infiltration in their daily practice. Methods A survey study in which shoulder and elbow specialists answered a questionnaire on the use of infiltration in painful shoulders. Results Most of the doctors (45.9%) have > 10 years of experience in the area and have carried out up to 10 infiltrations in the last 12 months. The main indications for glenohumeral and subacromial infiltration are glenohumeral arthrosis and rotator cuff tendinopathy, respectively. The most used portals are the posterior (52.2%) for glenohumeral infiltration and the lateral (57.5%) for subacromial infiltration. The majority of the doctors (752%) infiltrate in an outpatient setting without imaging methods, and the most commonly used drug is the combination of corticoid and anesthetic. The main contraindication cited is the presence of diabetes, and the most common complication is pain after infiltration. Conclusion Subacromial infiltrations are indicated especially for the treatment of rotator cuff tendinopathies and bursitis, performed by the lateral portal, in an outpatient setting, with low index of long-term complications. Glenohumeral infiltrations are indicated especially for glenohumeral arthrosis, with a combination of a corticoid and anesthetic, performed mostly in an outpatient setting.

Resumo Objetivo Avaliar como especialistas de ombro têm utilizado a infiltração na sua prática diária. Métodos Estudo tipo survey interseccional em tempo único, no qual especialistas em ombro e cotovelo responderam a um questionário sobre o uso de infiltrações no ombro doloroso. Resultados A maior parte (45,9%) dos entrevistados possui experiência > 10 anos na área e realizaram até 10 infiltrações nos últimos 12 meses. As principais indicações para infiltração glenoumeral e subacromial são artrose glenoumeral e tendinopatia do manguito rotador, respectivamente. Os portais mais utilizados são o posterior (52,2%) para infiltração glenoumeral e o lateral (57,5%) na subacromial. A maioria (75,2%) dos entrevistados realiza a infiltração ambulatorialmente sem auxílio de métodos de imagem, e a droga mais utilizada é a combinação de corticoide e anestésico. A principal contraindicação citada é a presença de diabetes, e a complicação mais comum é a dor após a infiltração. Conclusão Infiltrações subacromiais são indicadas especialmente para tratamento de tendinopatias do manguito e bursites, realizadas pelo portal lateral, em ambiente ambulatorial, com baixo índice de complicações em longo prazo. As infiltrações glenoumerais são indicadas especialmente para artrose glenoumeral, com combinação de corticoide e anestésico, realizadas, em sua maioria, ambulatorialmente.

Clinical Experimental Treatments for Arthrosis of the Carpometacarpal Joint of the Thumb Using Kampo Medicine / 日本東洋医学雑誌

Arthritis of the carpometacarpal joint of the thumb is typically treated with oral anti-inflammatory drugs, external medicines, and temporary external fixation. We report 3 cases of arthritis of carpometacarpal joint of the thumb that were successfully treated with sokeikakketsuto. In cases 1 and 2, a 50-year-old woman and 68-year-old man, respectively, were diagnosed with arthritis of the carpometacarpal joint and were successfully treated with sokeikakketsuto. In case 3, a 66-year-old man complained of pain in the second carpometacarpal joint caused by gout, and was successfully treated with eppikajutsuto and daiobotampito. However, the pain in the carpometacarpal joint of the thumb due to arthritis remained, and was successfully treated with sokeikakketsuto. Eppikajutsuto and daiobotampito were effective for acute arthritis such as gout, and sokeikakketsuto was effective for osteoarthritis. Overall, patients with different diseases in the various local regions may have slightly different clinical presentations even in the same case.

Difference in Articular Degeneration Depending on the Type of Sport / Diferença na degeneração articular de acordo com o tipo de esporte

Abstract Objective To determine whether type-II collagen degradation is determined by the type of sport. Carboxy-terminal telepoptide of type-II collagen (CTX-II), a serum biomarker of collagen degradation, was measured in athletes who play different sports, and was compared with matched controls. Methods The sample size consisted of 70 female participants aged between 18 and 25 years, 15 of whom were members of a soccer team, 10 of a futsal (a variant of association football played on a hard court) team, 10 of a handball team, 18 of a volleyball team, and 7 of a swimming team. A total of 9 age- and sex-matched individuals with sedentary lifestyles were included in the control group. 3-mL blood samples were collected from each participant, and they were analyzed using an enzyme-linked immunosorbent assay (ELISA). Results A comparison of the CTX-II concentrations of the players of different sports with those of the control group resulted in the following p-values: volleyball (p = 0.21); soccer (p = 0.91); handball (p = 0.13); futsal (p = 0.02); and swimming (p = 0.0015). Therefore, in the investigated population, futsal represented the highest risk for type-II collagen degradation and, consequently, for articular cartilage degradation, whereas swimming was a protective factor for the articular cartilage. No statistically significant difference was found in the body mass index among the groups. Conclusion Futsal players are exposed to greater articular degradation, while swimmers exhibited less cartilage degradation compared with the control group in the study population, suggesting that strengthening the periarticular muscles and aerobic exercise in low-load environments has a positive effect on the articular cartilage.

Resumo Objetivo Determinar se a degradação de colágeno tipo II é determinada pelo tipo de esporte. O telopeptídeo carboxiterminal do colágeno tipo II (CTX-II), biomarcador de soro de degradação de colágeno, foi medido em atletas de esportes diferentes e comparado aos controles correspondentes. Métodos A amostra consistiu em 70 participantes do sexo feminino com idade entre 18 a 25 anos, das quais 15 eram membros de uma equipe de futebol, 10 de uma equipe de futebol de salão, 10 de uma equipe de handebol, 18 de uma equipe de voleibol, e 7 de uma equipe de natação. Foram incluídos no grupo de controle 9 indivíduos sedentários, pareados por idade e sexo. Uma amostra de sangue de 3 ml foi coletada de cada participante e analisada usando um ensaio imunossorvente ligado a enzima (ELISA, do inglês enzyme-linked immunosorbent assay). Resultados Uma comparação das concentrações de CTX-II das praticantes de diferentes esportes em comparação com o grupo de controle apresentou os seguintes valores de p: voleibol (p = 0,21); futebol (p = 0,91); handebol (p = 0,13); futebol de salão (p = 0,02) e natação (p = 0,0015). Portanto, na população investigada, o futebol de salão apresentou o maior risco de degradação do colágeno tipo II, e, consequentemente, de degradação da cartilagem articular, enquanto a prática de natação foi um fator protetor para a cartilagem articular. Não foi observada diferença estatisticamente significativa no índice de massa corporal entre os grupos. Conclusão As jogadoras de futebol de salão estão expostas a uma maior degradação articular, enquanto as nadadoras apresentam menor degradação da cartilagem em comparação com o grupo de controle na população estudada, o que sugere que o fortalecimento dos músculos periarticulares e o exercício aeróbico em ambientes de baixa carga têm um efeito positivo na cartilagem articular.

Cirugía robótica en artroplastia de rodilla / Robotic surgery in knee arthroplasty

La cirugía protésica de rodilla es un procedimiento ampliamente aceptado como etapa final del tratamiento de la artrosis de rodilla, con sobrevida que supera el 90% a 10­15 años. Dentro de las principales causas de fallo, se encuentran la infección (20,4%) y el aflojamiento mecánico (20,3%). El uso de ayudas tecnológicas en cirugía está en constante desarrollo, con el objetivo de mejorar la precisión del acto quirúrgico. En ese escenario, la Cirugía Asistida por Computador (CAS) en artroplastia de rodilla, crece de forma exponencial, y apunta a mejorar el posicionamiento y selección del tamaño de los componentes protésicos, aumentar la precisión de las resecciones óseas y mejorar el balance de los tejidos blandos, logrando así una mayor sobrevida del implante. En comparación a las técnicas convencionales, la cirugía robótica ha mostrado mejores resultados funcionales, al primer año de seguimiento, en términos de rango articular, menor dolor post-operatorio y menor tiempo de estadía hospitalaria. Pero todavía es necesario establecer si, a largo plazo, esas diferencias funcionales se traducirán en mejores resultados clínicos que permitan, de forma consistente, inclinar la balanza en favor de la técnica asistida por robot por sobre las técnicas tradicionales.

Prosthetic knee surgery is a widely accepted procedure as the final stage in the treatment of knee osteoarthritis, with survival rate over 90% at 10 - 15 years. Among the main causes of failure are infection (20.4%) and mechanical loosening (20.3%). The use of technological aids in surgery is in constant development, with the aim of improving the accuracy of the surgical act. In this scenario, Computer-Aided Surgery (CAS) in knee arthroplasty grows exponentially, and aims to improve the positioning and selection of the size of the prosthetic components, increase the accuracy of bone resections and improve the balance of soft tissues, thus achieving a greater survival of the implant. Compared to conventional techniques, robotic surgery has shown better functional results at the first year of follow-up, in terms of joint range, less post-operative pain and shorter hospital stay. It is still necessary to establish whether, in the long term, these functional differences will result in better clinical results that will allow - in a consistent manner - to tip the balance in favor of robot-assisted technique over traditional techniques.

Carpectomía proximal en paciente con artrosis de muñeca / Proximal row carpectomy in patient with wrist osteoarthritis

Resumen: La artrosis de la muñeca es un proceso degenerativo, postraumático o idiopático que provoca al paciente dolor, pérdida de la movilidad, inflamación y deformidad. Las opciones quirúrgicas incluyen: artrodesis total de muñeca que produce una mejoría del dolor y disminución de la inflamación, otros tratamientos que permiten movilidad relativa son las artrodesis parciales. Otra solución quirúrgica es la carpectomía o la resección de la primera hilera del carpo, de tal manera que constituya una nueva articulación entre el radio y la segunda fila del carpo, obteniendo una congruencia articular adecuada. Material y métodos: Estudio observacional, descriptivo, serie de casos. Se valoraron 15 pacientes con carpectomía proximal durante el período de Enero de 2007 a Agosto de 2009, a quienes se realizó medición de arcos de movilidad y fuerza mediante las escalas de Mayo-DASH. Resultados: En 80% de los pacientes entre 35 y 64 años se encontró predominio del sexo masculino en 67%. La mejoría del dolor fue evidente, pasando de una media 7.7 en el preoperatorio a 2.7 en el postoperatorio, 10% de los casos presentaron dolor residual. Conclusiones: La carpectomía proximal representa una alternativa terapéutica que permite conservar la movilidad con mejora del dolor en la artrosis de muñeca.

Abstract: The arthrosis of the wrist is a degenerative, traumatic or idiopathic process, which cause problem for patient characterized by pain, loss of mobility, swelling and deformity of the affected wrist. A surgical alternative is proximal row carpectomy, which consists of resection of the lunate, scaphoid and triquetrum, forming a new joint between the radius and the distal row carpus. Material and methods: Observational, descriptive, case series. 15 patients were evaluated who underwent proximal row carpectomy during the period January 2007-August 2009, with clinical follow-up until august 2010 through mayo and DASH scores, measuring strength. Range of motion and pain. 80% of patients were between 35 and 64 years. The predominant sex was male in 67%. The result was satisfactory in 73%, according to the scale of Mayo. The DASH scale in the postoperative period also improves. Conclusions: The proximal carpectomy is a surgical alternative, it preserves some joint mobility, reduced pain and improved disability of the limb.

Frecuencia de infecciones en los pacientes con patología reumatológica del IAHULA Mérida 2016-2017

Introducción: Las infecciones se ha señalado que son causa de la descompensación de algunas enfermedades del tejido conectivo. Objetivos: Describir la frecuencia de infecciones asociadas a las diversas patologías reumatológicas en los pacientes que acuden al Hospital Universitario de Los Andes. Métodos: Estudio retrospectivo en el que se revisaron 3 328 historias clínicas pertenecientes a los pacientes del servicio de Reumatología. Resultados: La mayor parte de los pacientes eran del género femenino. La principal patología reumatológica fue artritis reumatoide, seguido del lupus eritematoso sistémico, artrosis en 3 lugar y finalmente otras entidades. Las principales infecciones fueron las del tracto urinario, en segunda instancia piel y partes blandas, en tercer lugar neumonías y en último lugar las no incluidas anteriormente. En cuanto al uso de la terapéutica y el tipo de patología reumatológica se encontró significancia estadística P 0,001. En cuanto al tipo de infección y la patología reumatológica en la cual se presentó dicho evento el valor de P fue 0,724. La principal causa de hospitalización en los 4 grupos de pacientes fue debido a causas infecciosas con un valor de P de 0,001. Discusión: Las infecciones fueron la principal causa de hospitalización en estos pacientes. La infección es causa de morbimortalidad importante en los pacientes reumatológicos. Conclusiones: Se recomienda en base a las observaciones obtenidas en el presente estudio, se evalúen a través de sistemas de estratificación los riesgos para el desarrollo de infecciones en los pacientes reumatológicos y así generar estrategias que disminuyan su frecuencia.

Introduction: Infections have been reported to be the cause of the decompensation of some connective tissue diseases. Objectives: To describe the frequency of infections associated with the rheumatological pathologies in patients of the University Hospital of the Andes. Methods: Retrospective study in which 3 328 clinical histories belonging to the patients of the Rheumatology service were reviewed. Results: Most of the patients were female. The main rheumatological pathology was Rheumatoid Arthritis, followed by Systemic Lupus Erythematosus, Arthrosis in third place and finally other entities. The main infections were those of the urinary tract, secondly skin and soft tissues, thirdly Pneumonia and lastly not previously included. Regarding the use of therapeutics and the type of rheumatological pathology, statistical significance was found P 0.001. Regarding the type of infection and the rheumatological pathology in which the event was presented, the P value was 0.724. The main cause of hospitalization in the 4 groups of patients was due to infectious causes with a p-value of 0.001. Discussion: Infections were the main cause of hospitalization in these patients. Infection is an important cause of morbidity and mortality in rheumatological patients. Conclusions: It is recommended based on the observations obtained in the present study, the risks for the development of infections in rheumatological patients be evaluated through stratification systems and generate strategies that decrease their frequency.

Resultados funcionales en artrosis patelofemoral aislada tratados mediante artroscopía más osteotomía de Fulkerson vs artroplastía patelofemoral / Functional results in isolated patellofemoral arthrosis treated by arthroscopy plus Fulkerson osteotomy vs patellofemoral arthroplasty

Resumen: Objetivo: Comparar los resultados clínicos de la artroplastía patelofemoral y la osteotomía de Fulkerson. Material y métodos: Se trataron 32 pacientes con el diagnóstico de artrosis patelofemoral aislada, 16 con artroplastía patelofemoral y 16 con osteotomía tipo Fulkerson, siendo una muestra no probabilística de conveniencia y de cuota con asignación aleatoria. Las indicaciones para cirugía fueron artrosis patelofemoral grado III-IV de la clasificación Kellgren-Lawrence, lo cual se trató con terapia farmacológica y rehabilitación física sin mejoría de la sintomatología. Las evaluaciones clínicas se realizaron previo a procedimiento quirúrgico, a los seis meses, un año y dos años, con los cuestionarios de Japanese Knee Injury and Osteoarthritis Outcome Score, Lysholm Knee Score y escala visual análoga. Resultados: Se encontró una mejoría significativa en ambos grupos. El componente de dolor mejoró significativamente en ambos grupos a los seis meses, un año y a los dos años (p ≤ 0.001 para ambos), dolor (p = 0.001), actividades diarias (p = 0.001), deportes (p = 0.001). La calidad de vida mejoró (p = 0.001), la correlación entre la puntuación al seguimiento a un año de dolor en el grupo de pacientes tratados con artroplastía patelofemoral en la escala de Lysholm y la subescala de dolor de KOOS (R2 = 0.8508). Una correlación moderada en las dimensiones de dolor y deporte de la escala KOOS (R2 = 0.783). Discusión: En nuestro grupo de estudio, la artroplastía patelofemoral presenta una mejor función, así como una disminución del dolor en comparación con la artroscopía y osteotomía tipo Fulkerson en todas las etapas de seguimiento.

Abstract: Objective: To Compare the clinical outcomes of patellofemoral arthroplasty and Fulkerson osteotomy. Material and methods: 32 patients with the diagnosis of isolated patellofemoral arthrosis were treated, 16 patients with patellofemoral Arthroplasty and 16 patients with Fulkerson type osteotomy. Being a non-probabilistic sample of convenience and quota with random allocation. The indications for surgery were osteoarthritis patellofemoral grade III-IV of the classification Kellgren-Lawrence, treated with pharmacological therapy and physical rehabilitation without improvement of the symptomatology. Clinical evaluations were performed prior to surgical procedure at six months, one year and two years. With the questionnaires of Japanese Knee Injury and Osteoarthritis Outcome Score, Lysholm Knee Score and analogue visual scale. Results: Significant improvement was found in both groups The pain component improved significantly in both groups at six months, one year and at two years (p ≤ 0.001 for both), daily activities (p = 0.001), sports (p = 0.001). The quality of life improved (p = 0.001). correlation between one-year follow-up score in the group of patients treated with patellofemoral arthroplasty on the Lysholm scale and the KOOS pain subscale (R2 = 0.8508). A moderate correlation in pain and sport dimensions on the KOOS scale (R2 = 0.783). Discussion: In our study group, patellofemoral arthroplasty exhibits better function as well as a decrease in pain compared to arthroscopy and Fulkerson's osteotomy at all stages of follow-up.

Artroplastia total de rodilla con defecto angular extraarticular. Reporte de caso / Total knee arthroplasty with extra-articular angular deformity. Case report

Establecer cuales deformidades angulares en el fémur deben ser tratadas con resección ósea intraarticular inusual más artroplastia total de rodilla en artrosis tricompartimental de rodilla es uno de los retos mayores que se enfrenta en cirugía ortopédica. Presentamos el caso de un paciente masculino de 67 años de edad, con antecedente de fractura diafisaria de fémur hace 30 años tratada en forma conservadora con dolor en la rodilla izquierda de 2 años de evolución con un diagnóstico de artrosis tricompartimental de la rodilla asociada a genu valgum de 20° y consolidación viciosa en diáfisis femoral izquierda con valgo femoral de 10°. El tratamiento quirúrgico realizado fue utilizando cortes intraarticulares inusuales y artroplastia total de rodilla. De acuerdo a la escala propuesta por la Knee Society Score el paciente obtuvo 89 al año de la cirugía. Ante deformidades femorales de hasta 20°, suele ser suficiente realizar la corrección con los cortes óseos intraarticulares (inusuales) evitando afectar las inserciones ligamentarias femorales.

To establish the angular deformities in the femur that should be treated with unusual intra-articular bone resection plus total knee arthroplasty in tricompartmental arthrosis of the knee is one of the major challenges faced in orthopaedic surgery. The case is presented of a 67 year-old male patient with a history of diaphyseal fracture of the left femur (30 years ago) treated conservatively with malunion in left femoral diaphysis with 10° femoral valgus and left knee pain of 2 years onset. He was diagnosed with tricompartmental osteoarthritis of the knee associated with genu valgum of 20°. Surgical treatment was performed using intra articular «unusual¼ bone cuts and total knee arthroplasty. According to the scale proposed by the Knee Society Score, the patient obtained a score of 89 one year after surgery. In femoral deformities of up to 20°, it is usually sufficient to perform the correction with intra articular «unusual¼ bone cuts, and avoiding affecting the femoral ligament insertions.

Comportamiento de pacientes con artrosis patelofemoral / Behavior of patients with patellofemoral osteoarthritis

Resumen: Antecedentes: La artrosis patelofemoral es detectada en un gran número de pacientes y es responsable de múltiples síntomas y signos entre los que predomina el dolor, su tratamiento es variado y va desde el conservador hasta el quirúrgico, en el que destaca la vía artroscópica. Objetivo: Mostrar el comportamiento de un grupo de pacientes con artrosis patelofemoral. Material y métodos: Se realizó un estudio observacional descriptivo en 96 pacientes con el diagnóstico clínico y radiográfico de artrosis patelofemoral desde Enero de 2015 hasta Abril de 2017. La muestra no probabilística e intencionada quedó constituida por 77 pacientes que reunieron los criterios de selección (inclusión y exclusión). Resultados: El promedio de edades fue de 52.2 años, predominó el sexo femenino, la rótula derecha y la causa que más se observó fue la primaria. El dolor durante el reposo es una de sus principales manifestaciones. Existe correlación entre la clasificación de Iwano T y Outerbridge RE. Por lo general, existen otros compartimentos afectados de la articulación, la presencia aislada es muy infrecuente y el tratamiento por vía artroscópica es de gran utilidad. Conclusiones: La artrosis patelofemoral es frecuente, genera síntomas y signos en un grupo grande de pacientes. La presencia de esta afección por lo regular está asociada a otras lesiones de la articulación y los enfermos pueden ser tratados por vía artroscópica.

Abstract: Background: Patellofemoral osteoarthritis affects a great number of patients complaining chiefly of knee pain, treatment vary from conservative to surgical, especially arthroscopy. Objective: The aim of this study was to show the behavior of a group of patients with patellofemoral osteoarthritis. Material and methods: A descriptive and transversal study with a level of evidence IV and recommendation grade C in the provincial teaching hospital Manuel Ascunce Domenech in Camaguey city from January 2015 to April 2017 was performed in 96 patients with the diagnosis of patellofemoral osteoarthritis, but 77 of them were selected as a non-probabilistic sample, based on selected criteria. Results: Mean age was 52.2 years. Female sex, right patella and primary etiology prevailed. Rest pain was the most common symptom. There is a strong correlation between Iwano T and Outerbridge RE classifications systems. In general, more than one compartment of the knee is affected in patellofemoral osteoarthritis, isolated presentation is rare and treatment by arthroscopy is of great help. Conclusions: Patellofemoral osteoarthritis is a common disease, patients usually complain of a great number of symptoms and signs. Patellofemoral osteoarthritis is usually associated to affection of other compartments and patients may be treated by arthroscopy.

Resultados funcionales de la doble artrodesis en deformidad del retropié: serie de casos / Functional results of Double arthrodesis in hindfoot arthrosis: Case series

Introducción La doble artrodesis es una técnica quirúrgica para el tratamiento de la artrosis del retropié con resultados equivalentes a la triple artrodesis. El objetivo fue describir los resultados funcionales en pacientes con diagnóstico de artrosis severa del retropié por diferentes causas. Materiales & Métodos Estudio tipo serie de casos de pacientes intervenidos con doble artrodesis entre 2012-2016. La mejoría clínica y funcional se evaluaron a través de la escala análoga del dolor (EVA) y la escala AOFAS del retropié; el estado actual de salud fue evaluado mediante la escala SF-12. Resultados Se incluyeron 14 pies en 12 pacientes (2 Hombres; 10 Mujeres) con un promedio de 62 años (Rango: 38-75 años). Se obtuvo una tasa de fusión del 93% y la principal causa etiológica fue la insuficiencia del tibial posterior. Todos los pacientes presentaron una mejoría significativa del dolor con una mediana EVA de 10 en el prequirúrgico (RIQ 9-10) a una mediana de 2 en el postquirúrgico (RIQ 0-4). El promedio de la escala AOFAS en el prequirúrgico fue 55 puntos en comparación a 76 puntos del postquirúrgico. El estado de salud actual con la escala SF12 reportó una puntuación promedio de 69.3 ± 19.7 en el componente físico y de 88.3 ± 15.6 en el componente mental. Discusión La doble artrodesis es una opción eficaz para el tratamiento de la artrosis del retropié mejorando la calidad de vida, intensidad de dolor y funcionalidad de los pacientes sometidos a esta intervención. Nivel de Evidencia: IV.

Introduction Double arthrodesis is a surgical technique for the treatment of hindfoot arthrosis with results equivalent to triple arthrodesis. The objective was to describe the functional results in patients with a diagnosis of severe hindfoot arthrosis for different causes. Methods Serial series of cases of patients operated with double arthrodesis between 2012-2016. Clinical and functional improvements were assessed through the analog pain scale (VAS) and AOFAS scale of the hindfoot; The current health status was assessed using the SF-12 scale. Results We included 14 feet in 12 patients (2 Men, 10 Women) with an average of 62 years (Range: 38-75 years). A fusion rate of 93% was obtained and the main etiologic cause was posterior tibial insufficiency. All patients had a significant improvement in pain with a median EVA of 10 in the preoperative period (IQR 9-10) and a median of 2 in the postoperative period (IQR 0-4). The average AOFAS scale in the preoperative period was 55 points compared to 76 postoperative points. The current health status with the SF12 scale reported an average score of 69.3 ± 19.7 in the physical component and 88.3 ± 15.6 in the mental component. Discussion Double arthrodesis is an effective option for the treatment of hindfoot arthrosis, improving the quality of life, intensity of pain and functionality at these patients. Level of evidence: IV

Correlation between Ahlbäck radiographic classification and anterior cruciate ligament status in primary knee arthrosis / Correlação entre a classificação radiográfica de Ahlbäck e o estado de conservação do ligamento cruzado anterior em gonartrose primária

ABSTRACT OBJECTIVE: To correlate the Ahlbäck radiographic classification with the anterior cruciate ligament (ACL) status in knee arthritis patients. METHODS: The study evaluated 89 knees of patients who underwent total knee arthroplasty due to primary osteoarthritis: 16 male and 69 females, with mean age 69.79 years (53-87 years). Osteoarthritis was classified radiographically by the Ahlbäck radiographic classification into five grades. The ACL was classified in the surgery as present or absent. The correlation of ACL status and Ahlbäck classification was assessed, as well as those of ACL status and the parameters age, gender, and tibiofemoral angulation (varus-valgus). RESULTS: In cases of varus knees, there was a correlation between grades I to III and ACL presence in 41/47 (86.7%) cases and between grades IV and V and ACL absence in 15/17 (88.2%) cases (p < 0.0001). In valgus knees, no statistically significant correlation was observed between the ACL status and the Ahlbäck classification. In the present study, absence of the ACL was more common in men (9/17; 52%) than in women (19/72; 26%). CONCLUSION: In cases of medial osteoarthritis, the Ahlbäck radiographic classification is a useful parameter to predict ACL status (presence or absence). In gonarthritis in genu valgum, ACL status was not predicted by Ahlbäck's classification.

RESUMO OBJETIVO: Correlacionar a classificação radiográfica de Alhbäck com o estado de conservação do ligamento cruzado anterior (LCA). MÉTODOS: Avaliados 85 pacientes (89 joelhos) submetidos à artroplastia total de joelho por osteoartrose primária. Foram 16 homens e 69 mulheres com média de 69,79 anos (53 a 87). A osteoartrose foi subdividida em cinco graus de acordo com a classificação radiográfica de Ahlbäck. O LCA foi avaliado na cirurgia como presente ou ausente. Foi feita a correlação entre o estado do LCA e a classificação de Ahlbäck. Foi também analisada a correlação entre o estado do LCA e os parâmetros idade, sexo, angulação tibiofemoral (varo-valgo). RESULTADOS: Nos casos de joelho varo, foi observada uma correlação entre os graus I até III e a presença do LCA em 41/47 (86,7%) casos, bem como entre a ausência do LCA e os graus IV e V em 15/17 (88,2%) casos (p < 0,0001). Por outro lado, nos casos de joelho valgo não houve relação estatisticamente significante entre a presença ou ausência do LCA e a classificação de Ahlbäck. Nesta série, foi observado que a ausência do LCA foi mais comum entre os homens 9/17 (52%) do que em mulheres 19/72 (26%). CONCLUSÕES: Nos casos de gonartrose do compartimento medial, a classificação de Ahlbäck é parâmetro confiável para prever a condição do LCA (presente ou ausente). Nos casos de gonartrose em genu valgo não se observou correlação entre a classificação de Ahlbäck e a condição do LCA.

A Metastatic Lung Adnocarcinoma Misdiagnosed as Trauma Induced Sternoclavicular Joint Arthrosis / 대한스포츠의학회지

The prevalence of metastatic tumorous lesion at medial clavicle or sternoclavicular joint is low. Herein, we presented a 45-year-old female patient with left sternoclavicular joint pain followed a weight-lifting exercise. The patient was initially diagnosed as traumatic sternoclavicular arthrosis, however, on later computed tomography scan demonstrated the bony destruction of medial clavicle which was diagnosed as metastasized non-small cell lung carcinoma after a fine needle biopsy.