RESUMEN
【Objective】 To retrospectively analyze the quality status and annual trend of provincial-level centralized blood screening across Ningxia, and discuss the effect and advantages of the application of centralized blood screening. 【Methods】 The centralized detection, with the combination of enzyme linked immunosorbent assay (ELISA) and nucleic acid test(NAT), in Ningxia from 2016 to 2020 was statistically analyzed, and the sample size, overall unqualified rate and unqualified rate of each item were compared among different regions. 【Results】 There were about 70 000 samples in Ningxia annually, 65% were in Yinchuan city, and 35% in Shizuishan, Wuzhong, Guyuan and Zhongwei city. The unqualified rates of blood screening in above five cities were 1.09% (2 438/223 852), 1.48% (401/27 024), 1.50% (425/28 364), 1.01% (351/34 772) and 1.45% (435/30 002) respectively. Significant differences were noticed in the unqualified rates of HBsAg, anti-HCV, anti-TP, HIV Ab/Ag, ALT and HBV DNA (P0.05) among the five cities. 【Conclusion】 Centralized blood screening at provincial-level in Ningxia can optimize the allocation of laboratory resources and better ensure blood safety, which is of great significance to the construction of urban public health system in Ningxia.
RESUMEN
【Objective】 To retrospectively analyse the quality status and annual trend of centralized blood screening across the regions of Hubei province, and discuss the effect and advantages of the application of centralized blood screening across blood establishment. 【Methods】 Blood screening results of five blood establishment across Hubei province from 2005 to 2019 were statistically analyzed. The sample size, overall rate of qualified blood donations, overall and annual rate of positive testing items were compared among regions. 【Results】 There were differences in blood quality among different regions of Hubei province. In Wuhan, Ezhou, Xiantao, Tianmen and Qianjiang, the overall rate of qualified blood donations was 97.1%(2 466 396/2 538 871), 96.5%(85 405/88 547), 95.2%(59 087/62 047), 95.5%(68 920/72 146) and 94.7%(34 274/36 188), respectively; the overall deferral rate of ALT was 1.472% (37 374/2 538 871), 2.024% (1 792/88 547), 2.840% (1 762/62 047), 2.476% (1 786/72 146) and 3.777% (1 367/36 188), with significant differences across regions; the overall positive rate of HBsAg was 0.587% (14 897/2 538 871), 0.664% (588/88 547), 1.094% (679/62 047), 1.282% (925/72 146) and 0.862% (312/36 188), with significant differences across regions. The deferral rate of ALT showed a downward trend by year in these five regions from 2005 to 2019.An decreasing trend in the seroprevalence of HBV was noticed in Wuhan, Tianmen, and Qianjiang, HCV in Wuhan, Ezhou, and Tianmen, as well as syphilis infections in Wuhan. 【Conclusion】 Centralized blood screening can optimize the allocation of testing resources, reveal problems during blood collection and supply and improve the ability to guarantee blood safety. Future efforts are needed to expand the scope of centralized blood screening and seek for a centralized screening mode suitable for local situation.