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1.
Indian J Cancer ; 2023 Jun; 60(2): 245-247
Artículo | IMSEAR | ID: sea-221790

RESUMEN

We present the case report of a 58?year?old man with recurrent chondroid syringoma, which was histopathologically confirmed, who underwent exenteration surgery of the right eye. Furthermore, the patient was receiving postoperative radiation therapy, and presently there is no local and/or distant evidence of disease in the patient

2.
Artículo | IMSEAR | ID: sea-222218

RESUMEN

Chondroid syringomas are similar to mixed parotid tumors and present in both benign and malignant forms. Malignant chondroid syringoma (MCS) is a rare skin tumor that has a predilection for extremities, particularly in young women. It is even rarer to present as a scalp tumor with very few reported cases in the literature. We present a middle-aged woman, with a history of increasing fatigability of her right arm for the past 3 months who, on examination, was found to have scalp swelling and matted right posterior triangle lymph nodes. The working diagnosis on her was a large sebaceous cyst with secondary in the neck from an occult primary/non-Hodgkin抯 lymphoma. Preliminary fine-needle aspiration was inconclusive. Imaging followed by wide excision of the tumor and the nearby occipital node was done. The final histopathological diagnosis was MCS with secondary in the lymph node. These tumors are aggressive and metastasize early. Radical surgery is the only hope of cure as adjuvant treatment is yet to be standardized

3.
Artículo | IMSEAR | ID: sea-196225

RESUMEN

Chondroid syringoma (CS) also known as mixed tumor of the skin, is a rare benign adnexal tumor accounting for < 0.098%. Epithelial cells arranged in cords and tubules set in myxoid or chondroid stroma. Differentiation such as osteoid, sebaceous or mature adipocytes can be seen rarely. Hyaline cell rich is a rare variant of CS composed of cells with eosinophilic hyaline cytoplasm and plasmacytoid features. CS can have benign, atypical and malignant variants. The term atypical mixed tumor is recommended for those tumors which have histological features of malignancy such as infiltrative margin, satellite tumor nodules and tumor necrosis but without proven metastasis. Very few case reports of hyaline cellrich benign CS have been reported in the past, but to the best of our knowledge, possibly it is the first case of atypical hyaline cellrich CS of the little finger in a 65 year-old female showing divergent differentiation.

4.
Rev. ADM ; 73(2): 88-91, mar.-abr. 2016. ilus
Artículo en Español | LILACS | ID: lil-789839

RESUMEN

Paciente masculino de 81 años de edad que acudió a consulta con un cirujano dentista por presentar una lesión nodular, asintomática, firme y móvil en el labio superior del lado derecho. El sujeto refi rió tener la lesión desde la infancia, pero notó crecimiento lento en el último año. El diagnóstico clínico indicaba un adenoma pleomorfo, por lo que el individuo se sometió a biopsia escisional bajo anestesia local. El espécimen se envió a estudio histopatológico. La evolución del paciente fue satisfactoria, sin reincidencia de la lesión. El examen microscópico reveló la presencia de una neoplasia bien delimitada constituida pormúltiples estructuras ductales pequeñas en la dermis. Estos ductos se encontraban revestidos por dos hileras de células epiteliales planas y contenían cantidades variables de material amorfo en la luz. El estroma presentaba diferenciación condroide.


An 81-year-old male patient consulted a dental surgeon due to his presenting a fi rm, mobile, asymptomatic nodular lesion on the upper lip. The patient stated that he had had the mass since childhood but that it had grown slowly over the course of the previous year. The clinical diagnosis was pleomorphic adenoma, for which reason the patient underwent an excisional biopsy under local anesthesia. The specimen was sent for histopathological examination. The patient’s progress was satisfactory and there was no recurrence of the lesion. Micro-scopic examination revealed the presence of a well-defi ned neoplasm consisting of multiple small ductal structures located in the dermis. These ducts were lined with two rows of fl attened epithelial cells and contained varying amounts of amorphous material in the lumen. The stroma exhibited chondroid differentiation.


Asunto(s)
Humanos , Masculino , Anciano de 80 o más Años , Adenoma Pleomórfico/diagnóstico , Adenoma Pleomórfico/ultraestructura , Neoplasias de los Labios/clasificación , Biopsia/métodos , Servicio Odontológico Hospitalario , México , Procedimientos Quirúrgicos Orales
5.
Artículo en Coreano | WPRIM | ID: wpr-62964

RESUMEN

BACKGROUND: Chondroid syringoma is a rare benign tumor composed of epithelial and stromal elements. Studies of chondroid syringoma are lacking in Korea and controversy still exists regarding the stromal cell origins. OBJECTIVE: To investigate the clinicopathological and immunohistochemical characteristics of chondroid syringoma in Korea. METHODS: We included 23 patients who were diagnosed with chondroid syringoma. RESULTS: There was a predilection for males (M : F=2.3 : 1), and the mean patient age was 50.4+/-15.4 years (range 22~78 years), peaking in the forties. Of the 23 cases, 22 (95.7%) had it on the head and neck. There were 21 apocrine type cases and 2 eccrine type cases. Apocrine type cases showed decapitation secretion as well as follicular and sebaceous differentiations. Myxohyaline matrix was present in all cases, and in some cases, chondroid, lipomatous, and osseous metaplasias were also observed. In apocrine type cases, inner cell layers displaying tubuloglandular structures expressed cytokeratin, carcino-embryonic antigen, and epithelial membrane antigen, while outer cell layers expressed vimentin, S-100 protein, neuron-specific enolase, and smooth muscle actin. Stromal cell immunophenotypes were similar to those of the outer layer. CONCLUSION: Chondroid syringoma was most commonly observed on the head and neck in middle-aged males. The apocrine type was far more common than the eccrine type and showed various differentiating characteristics. The matrix may contain myxohyaline stroma with alterations, including chondroid, lipomatous, and osseous metaplasias. Our immunohistochemical study suggests that myoepithelial cells play an important role in the histogenesis of chondroid syringoma and matrix production.


Asunto(s)
Humanos , Masculino , Actinas , Adenoma Pleomórfico , Decapitación , Cabeza , Queratinas , Corea (Geográfico) , Metaplasia , Mucina-1 , Músculo Liso , Cuello , Fosfopiruvato Hidratasa , Proteínas S100 , Células del Estroma , Vimentina
6.
Rev. cir. traumatol. buco-maxilo-fac ; 13(4): 29-32, Out.-Dez. 2013. ilus
Artículo en Portugués | LILACS, BBO | ID: lil-792294

RESUMEN

O siringoma condróide é um tumor misto cutâneo, benigno e raro, com prevalência de aproximadamente 0,01% dos tumores de pele. Oitenta por cento dos siringomas condróides são encontrados em idosos, sendo que a proporção é de duas mulheres para cada homem. Frequentemente encontrado na região da cabeça e pescoço principalmente no couro cabeludo, face e nariz. Lesões no tronco e extremidades são extremamente raras. As lesões possuem entre 0,5 e 3 cm e são firmes e aderentes à pele, mas distinguível das demais estruturas. Neste artigo se relata um caso de uma lesão na região do lábio superior... (AU)


Chondroid syringoma is a rare benign skin mixed tumor, with a prevalence of approximately 0,01% of skin tumors. Eighty percent of chondroig syringoma are found in the elderly, and the ratio is two women for every man. Often found in the head and neck, especially on the scalp, face and nose. Typical clinical presentation of these tumours is a slow-growing, painless, firm, nonulcerated cutaneous or intracutaneous nodule (0.5-3 cm in size). This article reports a case of a lesion in the left upper lip area... 9AU)


Asunto(s)
Humanos , Masculino , Anciano , Adenoma Pleomórfico , Tabaquismo
7.
Artículo en Francés | IMSEAR | ID: sea-157521

RESUMEN

Primary pleomorhic adenoma (Chondroid syringoma) arising from the external auditory canal is very rare and because of the unremarkable clinical presentation, the diagnosis is often made after microscopic examination. We reviewed the worldwide literature and found that only forty one cases have been previously reported. In this report, we describe one such unusual case. The treatment of choice is wide local excision without esthetic or functional disruption of surrounding structures, followed by careful long-term post-operative observation of the clinical course.


Asunto(s)
Adenoma Pleomórfico/diagnóstico , Adenoma Pleomórfico/patología , Adenoma Pleomórfico/diagnóstico por imagen , Adenoma Pleomórfico/cirugía , Adulto , Conducto Auditivo Externo/patología , Conducto Auditivo Externo/diagnóstico por imagen , Humanos , Masculino , Literatura de Revisión como Asunto , Tomografía Computarizada por Rayos X
8.
Hosp. Aeronáut. Cent ; 7(2): 124-126, 2012. ilus
Artículo en Español | LILACS | ID: lil-716487

RESUMEN

Introducción: El siringoma condroide maligno es un tumor cutáneo muy infrecuente pero que debemos tener en cuenta en el diagnóstico diferencial de los tumores axilares. Objetivos: Se realiza el análisis y la presentación del siguiente caso clínico con el objetivo de considerar esta entidad como diagnostico diferencial de los tumores axilares.Presentación de Caso: Paciente de sexo femenino de 82 años que refiere la presencia de una tumoración cutánea en axila derecha de 3 años de evolución, con realización de biopsia (PUNCH) que informa infiltración por carcinoma moderadamente diferenciado. Se decide su exéresis quirúrgica.Discusión: El siringoma condroide maligno es un tumor infrecuente, pero puede dar metástasis, pero con prolongados tiempos de sobrevida. Prefiere las extremidades y el tronco. Su pronóstico es bueno cuando la exéresis es completa, aunque es necesario realizar un seguimiento completo de los pacientes.


Introduction: Malignant chondroid syringoma is a very rare skintumor but must be considered in the differential diagnosis of axillary tumors. Objectives: We performed the analysis and presentation of thefollowing clinical case in order to consider this entity in the differential diagnosis of axillaries tumors. Case Presentation:Female 82 years old patient referring the presence of a skin tumor in the right axilla for three years standing. Biopsy (PUNCH) reports moderately differentiated carcinoma infiltration. S urgical excision is decided. Discussion: Malignant chondroid syringoma is a rare tumor, but can metastasize, with prolonged survival times. It prefers limbs and trunk. Its prognosisis good when the removal is complete, but anyway it is necessary to follow up patients.


Asunto(s)
Humanos , Femenino , Anciano de 80 o más Años , Adenoma Pleomórfico/diagnóstico , Adenoma Pleomórfico/patología , Adenoma Pleomórfico/terapia
9.
Artículo en Coreano | WPRIM | ID: wpr-48930

RESUMEN

PURPOSE: To report a case of chondroid syringoma that involved the eyelid margin, was accompanied by cilia loss, and required differential diagnosis with other malignant eyelid masses. CASE SUMMARY: A 46-year-old woman presented with a recurrent mass in the right lower eyelid margin, which was observed 10 years earlier, where incision and curettage had already been performed twice. The mass was neither tender nor ulcerated, was brighter in color than the neighboring skin, and had a smooth surface with cilia loss. The pathologic findings obtained from an incisional biopsy were compatible with a dermoid cyst. Full-thickness excision of the eyelid mass and direct closure were subsequently performed. The pathologic diagnosis after excisional biopsy was chondroid syringoma because cystic structures in the chondroid stroma were observed.


Asunto(s)
Femenino , Humanos , Persona de Mediana Edad , Adenoma Pleomórfico , Biopsia , Cilios , Legrado , Quiste Dermoide , Diagnóstico Diferencial , Párpados , Piel , Úlcera
10.
Artículo en Coreano | WPRIM | ID: wpr-109518

RESUMEN

PURPOSE: Chondroid syringoma is a rare mixed tumor of the skin that was first described by Hirsch and Helwig (1961). Characteristically, it is composed of the proliferation of epithelial cells in a myxoid and chondroid matrix. Most lesions occur on the head and neck region, and their size may range from 0.5~3 cm. Since a chondroid syringoma presents similar characteristics to other masses on the head and neck region, it is significantly important to distinguish with other masses by a surgical biopsy. METHODS: A 51-year old woman presented with a painless nodular mass (0.5 x 0.5 x 0.5 cm) on the philtrum, which appeared during the previous year. The mass was treated with a laser without a surgical biopsy. However, the size of the mass showed no changes. Surgical excision under local anesthesia was performed and sent for histopathology. RESULTS: Gross examination showed a mass surrounded by a well developed capsule within the dermal layer. After complete excision without injury to the orbicularis oris muscle, the wound was covered with a local flap. The histology examination revealed numerous cuboid epithelial cells with tuboalveolar structures and keratinous cysts within a chondroid stroma. No recurrence or metastasis was observed at the follow-up visits. CONCLUSION: Chondroid syringoma is a rare mass on the face. An accurate diagnosis is essential for optimal treatment. This paper reports a case of a chondroid syringoma on the philtrum with a brief review of the relevant literature.


Asunto(s)
Femenino , Humanos , Adenoma Pleomórfico , Anestesia Local , Biopsia , Células Epiteliales , Estudios de Seguimiento , Cabeza , Queratinas , Labio , Músculos , Cuello , Metástasis de la Neoplasia , Recurrencia , Piel
11.
Korean Journal of Dermatology ; : 1118-1120, 2010.
Artículo en Coreano | WPRIM | ID: wpr-23197

RESUMEN

Chondroid syringoma is a myxoid tumor of the skin and the reported incidence of this is 0.098% among all the primary skin tumors. This tumor generally occurs in middle or old aged patients. A 15-year-old woman presented with a 2-year history of a 0.4x0.4 cm sized whitish papule on her nasolabial fold. The tumor was diagnosed as chondroid syringoma by histologic examinations. We present here a case of chondroid syringoma in an adolescent girl, and such a case has not been previously reported in the Korean medical literature.


Asunto(s)
Adolescente , Anciano , Femenino , Humanos , Adenoma Pleomórfico , Incidencia , Surco Nasolabial , Piel
12.
Artículo en Coreano | WPRIM | ID: wpr-64822

RESUMEN

Chondroid syringoma is a rare epithelial tumor with an adnexal gland origin, and it clinically presents as a slowly growing benign nodule. A 57-year-old woman presented with a 1-year history of 1x1 cm subcutaneous firm nodule on her scalp. The biopsy specimen showed a basophilic stroma and small tubular structures that were lined by a single layer of epithelium, small groups of epithelial cells and solitary epithelial cells. The tumor cells showed positive immunoreactivity for S-100. Herein, we report on a case of chondroid syringoma that histopathologically presented with small tubular lumina.


Asunto(s)
Femenino , Humanos , Persona de Mediana Edad , Adenoma Pleomórfico , Basófilos , Biopsia , Glándulas Ecrinas , Células Epiteliales , Epitelio , Cuero Cabelludo , Siringoma
13.
Indian J Dermatol Venereol Leprol ; 2009 Nov-Dec; 75(6): 600-602
Artículo en Inglés | IMSEAR | ID: sea-140471

RESUMEN

Eccrine spiradenoma (ES) very rarely presents in a linear or zosteriform distribution. It may be associated with foci of various other appendageal tumors. We report a 14-year-old boy who presented to us with multiple nodules in a linear distribution in the posterior aspect of the right lower limb since 2 years of age. The lesions became significantly painful for the past 2 years. Histopathology revealed dermal lobules of ES with smaller foci of chondroid syringoma.

14.
Artículo en Coreano | WPRIM | ID: wpr-653161

RESUMEN

Chondroid syringoma is a benign sweat gland tumor composed of a mixture of epithelial cells and mesenchymal tissue. It is most frequently located on the head and neck. Chondroid syringoma is usually present as a firm intradermal or subcutaneous nodule. Histologically, the epithelial component consists of tubulocystic structures and aggregates of epithelial cells as well as single scattered epithelial cells throughout the stroma. The treatment of choice is complete local excision. We report a case of chondroid syringoma presenting as a external auditory canal mass in 54 year old man with a brief review of literature.


Asunto(s)
Adenoma Pleomórfico , Conducto Auditivo Externo , Células Epiteliales , Cabeza , Cuello , Glándulas Sudoríparas
15.
Artículo en Coreano | WPRIM | ID: wpr-101995

RESUMEN

Chondroid syringoma is an uncommon, benign and adnexal tumor which is composed of a mixture of epithelial cells and mesenchymal tissue. The usual presentation is of an asymptomatic, slowly growing mass, typically located in the head and neck region. We report a case of chondroid syringoma located in the right heel of a 46-year-old male patient. The tumor grew over a 10-year period, increasing rapidly in size over the last few months. It was a skin colored, 4.5x5x4 cm-sized, hyperkeratotic hard pedunculated nodule. The diagnosis of giant chondroid syringoma was made by clinical and histopathological examination, which showed a tubular structure and solid nest composed by more than two layers of epithelial cells embedded in a myxoid-adipoid tissue. The tubular lumina contained small amounts of amorphous, eosinophilic material. Regarding previous reports, this is a quite rare case of benign chondroid syringoma due to it's unusually large size and rare location.


Asunto(s)
Humanos , Masculino , Persona de Mediana Edad , Adenoma Pleomórfico , Eosinófilos , Células Epiteliales , Cabeza , Talón , Cuello , Piel
16.
Korean Journal of Dermatology ; : 1221-1224, 2008.
Artículo en Coreano | WPRIM | ID: wpr-40583

RESUMEN

Chondroid syringoma is rare, benign tumor of the sweat gland. It clinically presents as intradermal or subcutaneous nodule on the head and neck, measuring 5 to 30 mm in diameter. Giant chondroid syringoma can be defined as chondroid syringoma that exceed 30 mm at the point of greatest diameter if it occurs on the head and neck area. Most chondroid syringomas on the head and neck do not exceed 30 mm in diameter. We herein, report a case of giant chondroid syringoma of the nose in an 87 year-old woman.


Asunto(s)
Femenino , Humanos , Adenoma Pleomórfico , Cabeza , Cuello , Nariz , Glándulas Sudoríparas
17.
J. bras. patol. med. lab ; J. bras. patol. med. lab;43(3): 191-194, maio-jun. 2007. ilus
Artículo en Portugués | LILACS | ID: lil-460976

RESUMEN

O siringoma condróide maligno, também designado tumor misto maligno da pele, é lesão extremamente rara com aproximadamente 40 casos descritos até o presente momento. Trata-se de neoplasia derivada das glândulas sudoríparas que acomete preferencialmente tronco e extremidades distais em pacientes na sexta década e predomina no sexo feminino. Relatamos um caso com os aspectos clínicos e histológicos característicos para familiarizar o patologista com esse diagnóstico, visto que essa neoplasia com freqüência apresenta metástases locais e/ou regionais (cerca de 60 por cento), sobretudo para linfonodos, pulmões e ossos; além disso, possui taxa de mortalidade de aproximadamente 25 por cento após curso evolutivo prolongado.


Malignant chondroid syringoma (malignant mixed tumor of the skin) is an extremely rare tumor. Approximately 40 cases have been described to date. It is a neoplasm originated from sweat gland. The tumor predominantly affects the trunk and distal extremities, arises in the sixth decade and shows a predilection for females. We relate one case with clinical and histopathologic typical features to alert the pathologist to this diagnosis, since this neoplasm has a metastasic rate of approximately 60 percent (lymph nodes, lungs and bones are predominantly affected) and a mortality of roughly 25 percent.


Asunto(s)
Humanos , Masculino , Persona de Mediana Edad , Adenoma Pleomórfico/diagnóstico , Adenoma Pleomórfico/patología , Enfermedades Raras/diagnóstico , Neoplasias de las Glándulas Sudoríparas/patología , Inmunohistoquímica
18.
Artículo en Coreano | WPRIM | ID: wpr-113006

RESUMEN

PURPOSE: Chondroid syringoma, previously known as 'mixed tumor of the skin', is a rare benign tumor. It usually presents an asymptomatic solitary firm intradermal or subcutaneous slowly growing nodule. It occurs frequently in the head and neck region of middle-aged men. We would like to report an uncommon chondroid syringoma about the clinical and histologic presentation. about the clinical and histologic presentation. METHODS: We experienced two cases of chondroid syringoma on the nose and the upper lip, each other. Both masses were totally excised with clear margin. RESULTS: On histologic examination, the masses showed a biphasic pattern-an epithelial component exhibiting apocrine/eccrine differentiation and a stromal component exhibiting myxoid/collagenous change-consistent with the diagnosis of chondroid syringoma. There have been no evidence of recurrence and malignant transformation during postoperative follow-up. CONCLUSION: There is no one distinctive clinical feature that is specific for chondroid syringoma. However, it should be included in the differential diagnosis of a solid nodule in head and neck region with long standing duration, such as epidermal inclusion cyst, pilomatrixoma, dermoid cyst, sebaceous cyst, neurofibroma, and basal cell carcinoma.


Asunto(s)
Humanos , Masculino , Adenoma Pleomórfico , Carcinoma Basocelular , Quiste Dermoide , Diagnóstico , Diagnóstico Diferencial , Quiste Epidérmico , Estudios de Seguimiento , Cabeza , Labio , Cuello , Neurofibroma , Nariz , Pilomatrixoma , Recurrencia
19.
Annals of Dermatology ; : 40-43, 2006.
Artículo en Inglés | WPRIM | ID: wpr-32312

RESUMEN

Chondroid syringoma is an uncommon, benign neoplasm of sweat gland origin. It clinically presents as a slowly-growing intradermal or subcutaneous nodule, and is usually observed on the head and neck of middle-aged to elderly people. Histologically, two types of chondroid syringoma can be recognized: one common type has tubular and cystic lumina and the other extremely rare type has small tubular lumina. We herein report a rare case of chondroid syringoma with small tubular lumina.


Asunto(s)
Anciano , Humanos , Adenoma Pleomórfico , Cabeza , Cuello , Glándulas Sudoríparas
20.
Artículo en Coreano | WPRIM | ID: wpr-648423

RESUMEN

Chondroid syringoma, or mixed tumor of skin is a benign cutaneous neoplasm of sweat gland origin. It is rare in incidence, and most frequently found at the head and neck area. It is usually present as a slowly growing, painless intradermal or subcutaneous nodule in patients between the ages of 20 and 60 years. Histologically, there are two types, which are tubular, branching lumina type and small, tubular lumina type, and it contains both epithelial and stromal component. The treatment of choice is complete local excision. We report a case of chondroid syringoma presenting as a nasal columellar mass in a 50 year old woman with a brief review of literature.


Asunto(s)
Femenino , Humanos , Persona de Mediana Edad , Adenoma Pleomórfico , Cabeza , Incidencia , Cuello , Nariz , Piel , Glándulas Sudoríparas
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