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AIM:To observe the preventive effects of aluminum phosphate gel and smectite powder on the side effects of erythromycin lactobionate via intervenous drop infusion for the gastrointestinal tract in children.METHODS:249 cases children with mycoplasmal pneumonia were randomly divided into three groups,aluminum phosphate gel group,smectite powder group and control group,83 cases in each group.The side effects of erythromycin lactobionate(abdominal pain,diarrhea,sicchasia,disgorging)for the gastrointestinal tract among three groups were observed.RESULTS:Compared with control group,the incidence rate of side effects was much lower in aluminum phosphate gel group and smectite powder group(P0.05).CONCLUSION:Aluminum phosphate gel and smectite powder significantly decrease the side effects of erythromycin lactobionate for the gastrointestinal tract in children,and especially the former,can be widely applied in pediatric clinic.
RESUMEN
OBJECTIVE:To study the stability of erythromycin lactobionate mixed with five kinds of infusion fluid at room temperature for 6 hours METHODS:Using microbioassay according to Chinese Pharmacopoeia(2000) RESULTS:The potency of erythromycin lactobionate in five kinds of fluid decreased to varying degrees when they were cultured at room temperature for 6 hours And the potency decreased most quickly when erythromycin lactobionate was mixed with glucose injection or glucose in NS CONCLUSION:Erythromycin lactobionate mixed with sodium chloride injection is more stable than that mixed with glucose injection or glucose in NS