RESUMEN
Objective To study bone remodeling behavior under different damage conditions. Methods A bone remodeling model under fatigue mechanism was proposed. By establishing a three-dimensional (3D) finite element model of the proximal femur and combining with the finite element method, the bone remodeling under three loading conditions was simulated, and the mechanical properties and density changes of the proximal femur were analyzed. Results The damage increased with the number of loading cycles increasing. Under different damage conditions, bone showed different remodeling behaviors. As a kind of repair mechanism, bone remodeling could make up for the loss of bone mass due to fatigue damage within a certain range. Conclusions The damage adaptive remodeling model proposed in this study can simulate the bone remodeling behavior under different damage conditions, and the overload absorption caused by excessive loading cycles. The study on the behavior of bone remodeling under fatigue damage can provide references for fracture prevention and postoperative rehabilitation treatment.
RESUMEN
Objective To construct a three-dimensional (3D) solid model of the cortical bone including osteons,verify the stress concentration effect of osteons,simulate and predict the stress concentration location under fatigue using finite element analysis (FEA).Methods The 3D solid model of the cortical bone including osteons was constructed in Pro/E wildfire 5.0,and local stress and strain distributions in the cortical bone under different axial compression were calculated and analyzed in ANSYS 12.0.Fatigue simulation on the selected locations was conducted to evaluate fatigue status of the model subjected to different fatigue loading intensities.Results Obvious stress concentration at the junction of osteon and the interstitical bone appeared under axial compressive loads,and the percentage of pathological local strain in the cortical bone increased with the axial compression increasing.Fatigue simulation on the selected locations demonstrated that bone fatigue risk during physiological or daily activities was very low,while a high fatigue or fracture risk might occur during high-intensity exercises or training.Conclusions The 3 D solid model of the cortical bone including osteons is successfully established,the stress concentration effect of osteons is verified,and the location of bone fatigue damage under strenuous exercise and its risk are predicted.These experimental results can provide references for training management and athletic fatigue damage prevention in military recruits and long distance running athletes.
RESUMEN
Objective To construct a three-dimensional (3D) solid model of the cortical bone including osteons, verify the stress concentration effect of osteons, simulate and predict the stress concentration location under fatigue using finite element analysis (FEA). Methods The 3D solid model of the cortical bone including osteons was constructed in Pro/E wildfire 5.0, and local stress and strain distributions in the cortical bone under different axial compression were calculated and analyzed in ANSYS 12.0. Fatigue simulation on the selected locations was conducted to evaluate fatigue status of the model subjected to different fatigue loading intensities. Results Obvious stress concentration at the junction of osteon and the interstitical bone appeared under axial compressive loads, and the percentage of pathological local strain in the cortical bone increased with the axial compression increasing. Fatigue simulation on the selected locations demonstrated that bone fatigue risk during physiological or daily activities was very low, while a high fatigue or fracture risk might occur during high-intensity exercises or training. Conclusions The 3D solid model of the cortical bone including osteons is successfully established, the stress concentration effect of osteons is verified, and the location of bone fatigue damage under strenuous exercise and its risk are predicted. These experimental results can provide references for training management and athletic fatigue damage prevention in military recruits and long distance running athletes.
RESUMEN
Bone, acting as the main load-bearing organ in human body, is of mechanical adaptability. It is prevalent but perilous that under fatigue loading, bone suffers from fatigue damage characterized as the initiation, propagation of micro-cracks, deterioration of bone mechanical properties or even stress fracture, which is commonly seen in long distance running of athletes, fitness training of military recruits and daily activities of the elderly. Bone fatigue damages exist in multi-levels of ultra-micro structure, microstructure and macrostructure. The anti-fatigue units in cortical bone (osteons) and cellular components (osteocytes) inside have been proved to play important roles in fatigue damage prevention, micro-cracks recognition and bone-targeted remodeling activation. Therefore, a general review and summing-up of relative research findings can help to provide a systematic understanding of fatigue behavior and corresponding repair process, and to give some useful references and insights for subsequent clinical researches aiming at prevention and treatment for bone fatigue damage.