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@#AIM: To investigate the effect of puerarin combined with lecithin complex iodine tablets on hemostasis in patients with fundus hemorrhage. <p>METHODS: Totally 66 patients with fundus hemorrhage who entered into our hospital from April 2016 to March 2017 were collected and randomly divided into 2 groups: group A and group B, 33 cases(50 eyes)in each group. Group A was treated with lecithin complex iodine tablets, and group B was treated with puerarin combined with lecithin complex iodine tablets. Plasma viscosity index, serum homocysteine(Hcy), total cholesterol(TC)and triglyceride(TG)were measured and compared within 2 groups. The therapeutic effects and adverse reactions were compared between 2 groups. <p>RESULTS: Before treatment, there were no significant differences in plasma viscosity, serum Hcy, TC and TG between 2 groups(<i>P</i>>0.05). After treatment, the high blood viscosity, low blood viscosity, low plasma viscosity, plasma viscosity, Hcy, TC and TG in 2 groups had decreased than before treatment(<i>P</i><0.001). Compared with group A, the high blood viscosity, low blood viscosity, plasma viscosity, Hcy, TC and TG had decreased(<i>P</i><0.05). The total effect of group B were better than group A(<i>P</i><0.05). The adverse reaction like thyroid changes, gastrointestinal reactions, mental excitement and bloating happened in 2 groups. There was no significant difference in the adverse reaction rate between 2 groups(<i>P</i>>0.05).<p>CONCLUSION: The efficacy of puerarin combined with lecithin complex iodine tablets in the treatment of fundus hemorrhage is significant, which is related to improving plasma viscosity and decreasing serum Hcy, TC and TG.
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OBJECTIVE@#To observe the clinical effect of ' -- needling technique for diabetic fundus hemorrhage.@*METHODS@#With before-after study design, 34 patients with diabetic eyeground hemorrhage were treated with basic treatment (oral administration of antidiabetic medication or insulin injections to ensure blood glucose in the normal range); in addition, acupuncture was given at bilateral Fengchi (GB 20), Taiyang (EX-HN 5), Jingming (BL 1), Cuanzhu (BL 2), Sanyinjiao (SP 6) and Hegu (LI 4). The ' -- needling technique was applied at Fengchi (GB 20); the heat reinforcing needling technique was applied at Taiyang (EX-HN 5); the slow needle insertion technique was applied at Jingming (BL 1); and the - needling technique was applied at Cuanzhu (BL 2); the neutral supplementation and draining method was applied at remaining acupoints. The acupuncture was given once a day, 6 times as one course, and totally 4 courses were given with an interval of 1 day between courses. The follow-up visit was 6 months after treatment. The TCM symptom scores, fundus examination results and vision improvement were observed before and after treatment, and the effect was observed.@*RESULTS@#Compared before treatment, the visual acuity, TCM symptom scores, fundus microaneurysm and hemorrhage points in 34 patients (68 eyes) were significantly improved after treatment (0.05).@*CONCLUSION@#' -- needling technique could improve symptoms, promote the absorption of fundus hemorrhage, and improve vision in patients with diabetic fundus hemorrhage.