RESUMEN
Infectious epidermal cyst (IEC) is one of the most common cutaneous cysts. It sometimes causes severe bacterial infection and requires incisional drainage under local anesthesia. We reviewed the short-term outcome of the severe IEC patients with the Japanese traditional medicine, hainosankyuto, instead of surgical drainage. We retrospectively examined 125 patients of IEC (52 males and 73 females) administered hainosankyuto (HST). No recurrence for a year after the inflammatory symptoms disappeared was defined as short-term cure. We compared the cure rate and the internal use period by gender, age, affected area, premedication of antibiotics, and complications of immunosuppressive therapy. Overall, 88 cases (70%) were short-term cured and the average oral administration was 14.6 days. There was no gender difference. In age-related analysis, the cure rate tended to be lower in the 30s-50s because of many dropouts. In the examination by site, the cure rate was significantly higher in the other site group (63/78 cases : 80%) than back and buttock group. The average oral administration period was longer in the back and buttock group, respectively. The cure rate was higher in the antibiotic premedication group. The average oral administration period was significantly shorter in the no premedication group. In immunosuppressive group, 21 of 24 patients (87.5%) were cured, which was significantly higher than normal group. There was no difference in average oral administration period between the two groups. Hainosankyuto treatment was beneficial for short-term cure of severe IEC.
RESUMEN
Night owl is one of the painful symptoms for cancer patients. Patients with advanced cancer, who tend to bed on bed rest, often sleep during the day and are awake at night, especially. Night owl may make worse the QOL of patients. We controlled night owl and cancer pain of a patient with advanced cancer by treatment with Kampo, Japanese herbal medicine. The case was a 53-year-old female patient with metastatic head and neck cancer. She tended to be a night owl. So, we administered maobushisaishinto and keishikaryukotsuboreito to her, because we regarded her as qi obstruction. During the night, she was able to sleep successfully. After that, administration of hainosankyuto and bukuryoingohangekobokuto reduced the use of rescue medication. Moreover, Kampo was useful for pain control.
RESUMEN
We report a case of pyoderma chronica capillitii successfully treated with shokenchuto. The patient was a 20-year-old man, who had been suffering from an abscess and hair loss in the occipital region of his scalp for the past 6 months ; the lesion was gradually enlarging and was 3×3 cm in diameter at presentation. He was diagnosed with pyoderma chronica capillitii by a dermatologist and treated with puncture and drainage, multiple courses of oral antibiotics, and focal injections of tetracycline twice, with no beneficial response. Furthermore, another similar abscess with hair loss appeared on his occipital scalp and a new similar nodule appeared on his right cheek. He consulted my clinic to receive Kampo therapy. His abdominal examination revealed spasm of the bilateral rectus abdominis ; his abdomen was remarkably hypersensitive. He felt tickling intensely on abdominal palpation. Based on these findings, he was treated with shokenchuto, and hainosankyuto was added to relieve his symptoms. After a month of therapy, the nodule on his cheek disappeared, and several months later, the two occipital lesions improved and growth of new hair was noted. With continued treatment, his scalp and hair lesions healed completely and no recurrence was noted. To our knowledge, there is no previous report on the treatment of pyoderma chronica capillitii with shokenchuto. Based on the Kampo diagnostic pattern, Kampo medicine can be a beneficial therapeutic option for pyoderma chronica in cases where standard treatments are ineffective.
RESUMEN
For the purpose of confirming the effectiveness of hainosankyuto against periodontitis, we induced periodontitis by treating carrageenin in the gingiva at the right mandibular first molar in the oral cavity of a rat. We administered 2900 mg/kg of hainosankyuto orally for 10 days, and then, examined the anti-inflammatory effect of hainosankyuto on periodontitis. The gingival condition was evaluated by photographing, and histopathological analysis was performed by pathological specimens of removed inflamed-sites after the final administration. As a result, swelling of the gingival was suppressed by hainosankyuto. The periodontal pockets became shallower. Erosion of the epithelial layer was improved. Extension of the epithelial process, decrease of inflammatory cells, and maturing of periodontal membrane were observed. In addition, decrease of the neutrophils, increase of blood vessels and decrease of the osteoclasts were also revealed by histopathological analysis. Furthermore, extension of the junctional epithelium leg and shortened distance of apical movement on junctional epithelium were observed. These results suggested that hainosankyuto would have an anti-inflammatory effect on periodontitis.
RESUMEN
We successfully treated a patient with palmoplantar pustulosis, with a combined formulation of hainosankyuto and maobushisaishinto. The patient was a 64-year-old female, who had frequently occurring pustulae of about 2 mm in size on her palms and soles, from about May 2000. These pustulae became a crust over time, and the skin peeled off and healed. However, pustulae would persist again every two weeks. We diagnosed this as palmoplantar pustulosis and administered hainosankyuto, but with limited results, whereupon we added maobushisaishinto. As a result of this combined hainosankyuto and maobushisaishinto formulation, our patient with palmoplantar pustulosis recovered significantly after 4 weeks.