RESUMEN
The present study was performed to evaluate the effect of Tetracycline-HCl on the change of implant surface microstructure according to application time. Implant with hydroxyapatite surface was were utilized. Implant surface was rubbed with 50mg/ml Tetracycline-HCl solution and sterilized saline for 1/2min., 1min., 1 1/2min., 2min., 2 1/2min. and 3min. respectively in the test group. Then, specimens were processed for scanning electron microscopic observation and measured surface roughness by optical interferometer. The results of this study were as follows. 1. Hydroxyapatite surface showed that round particles were deposited irregularly. 2. The roughness of surfaces conditioned with Tetracycline-HCl and saline was lessened and the cracks were increased relative to the application time. In conclusion, the detoxification with 50mg/ml Tetracycline-HCl must be applied respectively with appropriate time according to hydroxyapatite implant surfaces.