Protective Effect of Hyperoxia Liquid on Multiple Organ Damage during Ischemic Reperfusion Injury in Infants with Muggy Syndrome / 实用儿科临床杂志

0.05).But after the treatment,there were significant increases in pa(O2),SaO2 and PCIS(Pa0.05).Conclusions Early application of hyperoxia liquid could decrease multiple organ anoxia and the damage of lipid peroxidation.It has obviously protective effects on multiple organ damage during ischemic reperfusion in infants with muggy syndrome.

Effect of active oxygen on hepatocarcinoma tissues of rabbits / 中国普通外科杂志

80) via portal vein.After reperfusion 1 h,1 d,3d and 7 d respectively,the concentration of superoxide dismutase(SOD) and catalase(CAT) were tested,and the apoptosis of hepatocarcinoma also was observed using terminal deoxynucleotidyl transferase-mediated dUTP nick end-labeling(TUNEL) method.Results The results indicated that the SOD concentration in both hepatocarcinoma tissue and normal hepatic tissues decreased following I/R and perfusion with hyperoxic fluid liquid.The concentration of CAT increased following I/R in normal hepatic tissues.In hepatocarcinoma tissue,concentration of CAT decreased after reperfusion for 1 d and reached its lowest point.After perfusion with hyperoxic fluid,the concentration of SOD in both hepatocarcinoma tissue and normal hepatic tissues decreased more quickly following I/R and the low level was still found on 7 d after reperfusion.The concentration of CAT in tissues of both groups decreased and reached the lowest level at 1 h after reperfusion,but it was restored at 3 d reperfusion in normal hepatic tissues,and in hepatocarcinoma tissue was still at lower level until 7 d after reperfusion. After I/R,the apoptotic cells increased in normal hepatic and hepatic cancer tissues,and were most marked in tissues of hepatic carcinoma at 1 d and 3 d after perfusion with hyperoxic fluid.After I/R and perfusing with hyperoxic fluid,the changes of SOD and CAT and apoptosis in hepatocarcinoma tissue were more obvious than that in normal hepatic tissues(P

Effect of hyperoxia liquid preconditioning on malondialdehyde and super oxide dismutase during valve replacement with cardiopulmonary bypass / 西安交通大学学报(医学版)

Objective To observe the cardioprotective effects of hyperoxia liquid by comparing the changes of blood concentrations of malondialdehyde(MDA)and super oxide dismutase(SOD)in mechanical heart valve replacement.Methods Thirty patients required mechanical heart valve replacement were randomly divided into hyperoxia liquid group(Group HL) and control group 15 cases in each.From the start of skin incision(T_(0)) to(10min) after CPB,patients received 10mL/kg Ringer's injection(control group) and 10mL/kg hyperoxia liquid(Group HL) seperately.The central venous blood samples,which were collected in both groups respectively at skin incision(T_(0)),1h after start of CPB(T_1),2h(T_2) and 24h(T_3) after aorta off-clamping,were used to test the blood concentrations of SOD and MDA.Also a series of clinical data were recorded,such as the rate of heart automatic rebeat after aorta off-clamping,ventricular arrhythmia,usage of dopamine in operation and postoperation.(Results)In both groups,the blood concentrations of MDA and SOD were all within normal range before operation.MDA level at T_(2) was lower in Group HL than that in control(P