Restauração transcirúrgica: inter-relação periodontia e dentística / Transsurgical restoration: interrelationship between periodontics and dentistry

Tendo em vista a importância da relação Dentística Restauradora e Periodontia na Odontologia atual, o presente estudo demonstrou o relato de um caso clínico realizado no Complexo Odontológico do Centro Universitário da Serra Gaúcha (FSG), retratando um procedimento de restauração transcirúrgica em um paciente cujo elemento 13 estava comprometido com uma cavidade subgengival disto-palatino, sendo a resina composta o material restaurador de escolha. Este estudo teve como objetivo apresentar um caso clínico demonstrando a técnica de restauração transcirúrgica e a integração do planejamento entre Periodontia e Dentística Restauradora realizado na Clínica de Odontologia do Centro Universitário da Serra Gaúcha -FSG. Este trabalho mostrou a importância da realização de uma técnica cirúrgica e restauradora correta por parte dos cirurgiões-dentistas, assim como na verificação de que os tecidos periodontais podem reagir de forma positiva à presença de materiais restauradores adesivos posicionados subgengivalmente(AU)

In view of the importance of the restorative dentistry and periodontics relationship in current dentistry, the present study demonstrated the report of a clinical case carried out in the Dental Complex of the Centro Universitário da Serra Gaúcha - FSG, portraying a transsurgical restoration procedure in a patient whose element 13 was compromised with a subgingival cavity of this-palatine, the composite resin being the restorative material of choice. This study aimed to present a clinical case demonstrating the technique of transsurgical restoration and the integration of planning between Periodontics and Restorative Dentistry carried out at the Dentistry Clinic of the University Centro Universitário da Serra Gaúcha - FSG. This study showed the importance of performing a correct surgical and restorative technique by dentists, as well as in verifying that periodontal tissues can react positively to the presence of adhesive restorative materials positioned subgingival(AU)

Exploring of Transformation Rule of Saponins in Polygalae Radix Before and After Processing Based on Simulated Processing Technology / 中国实验方剂学杂志

ObjectiveTo investigate the transformation mechanism and content variation of saponins from Polygalae Radix before and after being boiled with licorice juice and water. MethodSimulated licorice juice boiled products and simulated water boiled products of onjisaponin B， onjisaponin Z， onjisaponin F， polygalasaponin ⅩⅩⅧ were prepared by simulated processing technology， and analyzed by ultra-performance liquid chromatography-quadrupole-electrostatic field orbitrap high resolution mass spectrometry（UPLC-Q-Exactive Orbitrap/MS）. Then the contents of onjisaponin B， onjisaponin Z， onjisaponin F， polygalasaponin ⅩⅩⅧ and tenuifolin in Polygalae Radix， licorice-boiled Polygalae Radix and water-boiled Polygalae Radix were determined by UPLC-triple quadrupole tandem mass spectrometry（UPLC-QQQ-MS/MS）. ResultDuring the boiling process with licorice juice and water， onjisaponin B could be hydrolyzed to produce 4-methoxycinnamic acid， desacylsenegin Ⅲ， polygalasaponin ⅩⅩⅧ and tenuifolin， onjisaponin Z could be hydrolyzed to produce 3，4，5-trimethoxycinnamic acid， onjisaponin TF， polygalasaponin ⅩⅩⅧ and tenuifolin， onjisaponin F could be hydrolyzed to produce 3，4，5-trimethoxycinnamic acid， onjisaponin G， polygalasaponin ⅩⅩⅧ and tenuifolin， and polygalasaponin ⅩⅩⅧ was hydrolyzed to produce tenuifolin. After being boiled with licorice juice or water， the content of onjisaponin B decreased significantly（P<0.05， P<0.01）， but the contents of onjisaponin Z， onjisaponin F， polygalasaponin ⅩⅩⅧ and tenuifolin increased significantly（P<0.05， P<0.01） in Polygalae Radix. Compared with the water-boiled products， the contents of onjisaponin Z and tenuifolin increased significantly（P<0.05， P<0.01）， and the change of tenuifolin content was the most significant in the licorice-boiled products.However， there was no significant difference in the content of onjisaponin B， onjisaponin F and polygalasaponin ⅩⅩⅧ between the water-boiled products and the licorice-boiled products. ConclusionBeing boiled with licorice juice or water can hydrolyze onjisaponin B， onjisaponin Z， onjisaponin F and polygalasaponin ⅩⅩⅧ， and generate secondary glycosides and aglycones（organic acids） through deglycosylation， which leads to obvious changes in the contents of onjisaponins after Polygalae Radix being processed.It is inferred that licorice juice can promote the hydrolysis of some onjisaponins in Polygalae Radix to onjisaponin Z and tenuifolin.This study provides an experimental basis for revealing processing mechanism of Polygalae Radix.

How does the increase of body mass and ageing affect sprinter's results in a 100 m run? / ¿Cómo afecta el aumento de la masa corporal y el envejecimiento a los resultados del velocista en una carrera de 100 m?

SUMMARY: The career of a sprinter is analyzed with U. Bolt achievements as an example. The effects of the increase of body mass and ageing are discussed within the framework of the polynomial models for the velocity, muscular isometric force and age. The analysis presented demonstrates the influence of the BM factor in analyzed racing. The nonlinear increase of the BM for 9 kg in the period 2009 - 2017 in was one of the reasons of Bolt's unsuccessful attempt to repeat or confirm the time 9.58 s. Another limiting factor was the fact that due to the age, Bolt was not able to increase isometric muscular force which, after the year of maximal efficiency (2009) decreased.

RESUMEN: La carrera de un velocista se analiza con los logros de U. Bolt como ejemplo. Los efectos del aumento de la masa corporal y el envejecimiento se discuten en el marco de los modelos polinomiales de velocidad, fuerza isométrica muscular y edad. El análisis presentado demuestra la influencia del factor MC en el análisis en las carreras. El aumento no lineal de la MC para 9 kg en el período 2009 - 2017 fue una de las razones del intento fallido de Bolt de repetir o confirmar el tiempo 9,58 s. Otro factor limitante fue el hecho de que debido a la edad, Bolt no fue capaz de aumentar la fuerza muscular isométrica que disminuyó luego del año de máxima eficiencia (2009).

Paraganglioma. Presentación de caso / Paraganglioma. Case presentation / Paraganglioma. Apresentação do caso

RESUMEN El Paraganglioma es un tumor poco frecuente de origen neuroectodérmico derivado del sistema nervioso autónomo. Acude a consulta paciente masculino de 52 años de edad, procedencia rural con antecedente de salud. El cual acude a la consulta, refiriendo que hace más menos 6 meses presenta un aumento de volumen en la región lateral izquierda del cuello, que fue aumentando de tamaño progresivamente, sin presentar dolor. Se le realizó biopsia incisiónal, que confirmó un Angioendotelioma papilar seromatoso; luego de la excerilisis presentó dehiscencia de la herida y aumento de tamaño de la lesión en forma de ulcerada de más menos 10cm, por lo que es remitido al Hospital Oncológico de Santiago de Cuba, centro donde se decide su inscripción para evaluar inicio de tratamiento oncoespecifico. En el examen de la lámina se diagnostica histopatológicamente un Ganglioma sugiriéndose estudio en centro de referencia nacional. Se aplicó tratamiento quirúrgico. El tratamiento de elección fue la cirugía con su embolización previa. Se recomendó seguimiento a largo plazo del paciente por el alto riesgo recurrente de enfermar.

ABSTRACT Paraganglioma is a rare tumor of neuroectodermal origin derived from the autonomic nervous system. A 52-year-old male patient, rural origin with a health history, comes to the office. The patient attended the consultation, reporting that for more than 6 months he had an increase in volume in the left lateral region of the neck, which was progressively increasing in size, without presenting pain. An incision biopsy was performed, which confirmed a seromatous papillary angioendothelioma; After excerilysis, he presented dehiscence of the wound and an increase in the size of the lesion in the form of an ulcerated lesion of more than 10cm, for which he was referred to the Oncological Hospital of Santiago de Cuba, a center where his registration was decided to evaluate the start of cancer-specific treatment . In the examination of the lamina a ganglioma is diagnosed histopathologically, suggesting study in a national reference center. Surgical treatment was applied. The treatment of choice was surgery with its prior embolization. Long-term follow-up of the patient was recommended due to the high recurrent risk of illness.

RESUMO O paraganglioma é um tumor raro de origem neuroectodérmica derivado do sistema nervoso autônomo. Paciente do sexo masculino, 52 anos, origem rural e histórico de saúde, chega ao consultório. O paciente compareceu à consulta, relatando que há mais de 6 meses apresentou aumento de volume na região lateral esquerda do pescoço, que foi aumentando de tamanho progressivamente, sem apresentar dor. Foi realizada biópsia incisional, que confirmou um angioendotelioma papilar seromatoso; Após a excerilise, apresentou deiscência da ferida e aumento do tamanho da lesão em forma de lesão ulcerada de mais de 10cm, pela qual foi encaminhado ao Hospital Oncológico de Santiago de Cuba, centro onde se decidiu seu cadastro para avaliar o início do tratamento específico do câncer . No exame da lâmina é feito o diagnóstico histopatológico de ganglioma, sugerindo estudo em centro de referência nacional. O tratamento cirúrgico foi aplicado. O tratamento de escolha foi a cirurgia com sua embolização prévia. O acompanhamento em longo prazo do paciente foi recomendado devido ao alto risco recorrente de doença.

Adherencia terapéutica en hipertensos con incremento matutino de la presión arterial / Therapeutic adherence in hypertensive patients with morning hypertension

Introducción: El incremento matutino de la presión arterial detectado por monitoreo ambulatorio se asocia a daño de órgano blanco y a una mayor incidencia de eventos cardiovasculares. Objetivo: Determinar la adherencia terapéutica en hipertensos con incremento matutino de la presión arterial. Métodos: Se realizó un estudio transversal en 195 pacientes hipertensos ingresados en el servicio de medicina interna del Hospital Universitario Calixto García en el año 2018. Estos mostraron incremento matutino de la presión arterial y se valoró la adherencia terapéutica mediante el test de cumplimiento autocomunicado de Morisky-Green-Levine. Las variables identificadas como predictores relevantes de no adherencia fueron introducidas en un modelo multivariado de regresión logística. Resultados: 63,6 por ciento de los pacientes con incremento matutino de la presión fueron no adherentes, predominaron los pacientes del sexo masculino, 71,6 por ciento. El 84,0 por ciento (p=0,00) de los no adherentes ingerían de 3 a 4 fármacos antihipertensivos, 90,2 por ciento (p=0,00) tomaban 3 o más dosis. 50,5 por ciento de los pacientes tenía un diagnóstico de más de 5 años. Conclusiones: Los pacientes con incremento matutino de presión arterial se caracterizaron por ser no adherentes a la terapéutica antihipertensiva(AU)

Introduction: The morning hypertension detected by ambulatory monitoring is associated with target organ damage and a higher incidence of cardiovascular events. Objective: To determine the therapeutic adherence in hypertensive patients with a morning hypertension. Methods: A cross-sectional study was carried out in 195 hypertensive patients admitted to the internal medicine service at Calixto García University Hospital in 2018. They showed a morning increase of blood pressure and therapeutic adherence was assessed using the self-reported compliance test by Morisky-Green-Levine. The variables identified as relevant predictors of non-adherence were entered in a multivariate logistic regression model. Results: 63.6 percent of the patients with morning hypertension were non-adherent. Male patients predominated. 71.6 percent 84.0 percent (p = 0.00) of the non-adherents had 3 to 4 antihypertensive drugs, 90.2 percent(p = 0.00) took 3 or more doses. 50.5 percent of the patients were diagnosed for more than 5 years. Conclusions: Patients with morning hypertension were described as non-adherent to antihypertensive therapy(AU)

Progresión de talla y peso en niños y niñas entre 6 y 12 años y su diferencia con las tablas de Ramos Galván 40 años después / Height and weight progression patterns in Mexican children aged between 6 and 12 years and differences with Ramos-Galvan growth charts 40 years later

Resumen Introducción: El peso y la talla de niños y adolescentes son un reflejo del estado de salud y desarrollo socioeconómico de la población. Objetivo: Evaluar las progresiones de talla y peso de niños y niñas mexicanos y compararlas con las tablas del doctor Ramos Galván a 40 años de distancia. Método: Encuesta transversal realizada en población del Programa Nacional de Activación Física Ponte al 100, que incluye niños y niñas de seis a 12 años. Resultados: Se evaluaron 43 670 niños y 44 103 niñas, que se estratificaron por sexo y edad. La progresión de talla entre los seis y 12 años fue de 21 cm en hombres y de 22 cm en mujeres; la progresión de peso fue de 9.86 y 10.05 kg, respectivamente para hombres y mujeres. La proporción de niños de seis y 12 años con sobrepeso fue de 11.2 y 9 % y con obesidad, de 14.7 y 15 %. La proporción de niñas de seis y 12 años con sobrepeso fue de 8.2 y 9.1 % y con obesidad, de 21.7 y 13.3 %, respectivamente. Al comparar los valores obtenidos con los de las tablas del doctor Ramos Galván para niños y niñas, el promedio de diferencia fue de 2 cm. Conclusiones: No se documentó un incremento secular de la talla ni del peso en los últimos 40 años.

Abstract Introduction: Children and adolescents weight and height are a reflection of the health status and socioeconomic development of a population. Objective: To evaluate height and weight progression patterns of Mexican children and compare them with Dr. Ramos-Galván growth charts 40 years later. Method: Cross-sectional survey conducted on the population of the National Physical Activation Program Ponte al 100, which includes boys and girls aged 6-12 years. Results: 43,670 boys and 44,103 girls were assessed, stratified by gender and age. The height progression pattern between six and 12 years was 21 cm in males and 22 cm in females, whereas the weight progression pattern was 9.86 and 10.05 kg, respectively, for males and females. The proportion of 6- and 12-year-old boys who were overweight was 11.2 and 9%, while 14.7 and 15% were obese. The proportion of 6- and 12-year-old girls who were overweight was 8.2 and 9.1%, whereas 21.7 and 13.3%, respectively, were obese. When the obtained values were compared with those of Dr. Ramos Galván growth charts for boys and girls, the average difference was 2 cm. Conclusions: No secular height or weight increase within the last 40 years was documented.

Perceptions of Spanish nurses on economic crisis and the impacts on health care system / Percepciones de enfermeras españolas acerca de la crisis económica y sus impactos en el sistema sanitario / Percepções de enfermeiras espanholas sobre a crise econômica e os impactos no sistema de saúde

ABSTRACT Objective: to analyze the perceptions of Spanish nurses regarding the country's economic crisis situation, and its impacts on nursing work, health system and population's health. Methods: qualitative approach, with data collection using an internet-based questionnaire and individual in-depth interviews. Data were analyzed according to Thematic-Categorical Content Analysis, supported by Historical and Dialectical Materialism perspective. Results: the categories produced discuss themes as: cutbacks in health care and the consequences of workforce non-replacement and work overload; salary impact; care model changes; negative impacts on population health. The impact on population health and work was discussed, especially regarding vulnerable groups, as well as in assistance model reconfiguration, reinforcing the biomedical and assistance perspective.

RESUMEN Objetivo: analizar las percepciones de las enfermeras españolas en cuanto a la coyuntura de crisis económica vivenciada por el país y sus impactos en el trabajo, en el sistema de salud y en la salud de la población. Métodos: enfoque cualitativo, con recolección de datos por medio de un cuestionario publicado en Internet y a partir de entrevistas individuales en profundidad. Los datos fueron analizados con base en el Análisis de Contenido Temático-Categorial, con suporte teórico del Materialismo Histórico y Dialético. Resultados: las categorías discuten temas como: los cortes financieros y sus impactos de no-reposición de la fuerza de trabajo, sobrecarga de trabajo, impacto salarial y en las plazas de trabajo; énfasis en un modelo asistencial biomedico; impactos negativos en la salud de la población. Se discutieron los impactos en el trabajo y la salud de la población, sobre todo en los grupos vulnerables, así como en la reconfiguración del modelo asistencial, reforzando la perspectiva biomédica y asistencial. Consideraciones finales: la perspectiva de la enfermería española apunta hacia el agravamiento de las políticas liberales y su expresión en la salud, y para el papel de la enfermería en los sistemas universales de salud.

RESUMO Objetivo: analisar as perceções de enfermeiras espanholas quanto à conjuntura de crise econômica e seus impactos no trabalho, no sistema de saúde e na saúde da população. Método: abordagem qualitativa; coleta de dados por questionário publicado na internet e em entrevistas individuais. Análise com base na Análise de Conteúdo Temático-Categorial, apoiada pela perspectiva teórica do materialismo histórico-dialético. Resultados: as categorias produzidas abordam temas como: cortes financeiros e seus impactos de não reposição da força de trabalho, sobrecarga de trabalho, impacto salarial e na oferta de emprego; ênfase em um modelo de saúde biomédico; impactos negativos na saúde da população. Discussão: destacam-se impactos no trabalho e na saúde, sobretudo nos grupos vulneráveis, assim como sobre o modelo assistencial reforçando a perspectiva biomédica. Considerações finais: as percepções da enfermagem espanhola apontam para o acirramento das políticas liberais e sua expressão na saúde e para o papel da enfermagem nos sistemas de saúde.

El control de la hipertensión arterial, aún sin definir / Arterial hypertension control: still without definition

RESUMEN El debate alrededor de las cifras de tensión arterial, y sobre todo las cifras a obtener mediante el tratamiento es en la actualidad un grave problema de salud. Se realizó una revisión sistemática en inglés y español de los principales artículos publicados en PubMed, Scielo y MEDLINE durante el periodo comprendido desde el año 2012 hasta 2018, acerca de la definición, evaluación y manejó de la tensión arterial. Todas las guías están de acuerdo en la toma de múltiples medidas de la tensión arterial para el diagnóstico, pero no para definir el control de la tensión, definir el control de la tensión arterial debe incluir una dimensión en el tiempo en un año por lo menos, y una proporción mínima de medidas donde debe pensar en la mitad de todas las medidas por lo menos, con medidas de tensión arterial tomadas por lo menos cada tres meses, por lo que sugerimos que un perfil anual de las cifras de tensión arterial debe ser considerado como un requisito mínimo para evaluar el control de la hipertensión arterial, este trabajo ha perfilado dos de los factores menos reconocidos: la necesidad de la intensificación del tratamiento después de la primera toma de tensión arterial por encima de las cifras deseadas, y el incremento de una nueva droga en vez de incrementar las dosis de las ya indicadas.

ABSTRACT The debate on the maintained arterial tension measure, and on the measure to obtain through the long term treatment, is currently a problem for the medical practitioner, due to the variation of arterial tension during the day at different hours because of the patients circadian cycle, and due to variations in different days according to the proper patient's situations or the environment around it, and the different seasons of the year. They make it difficult to know when arterial tension is within the parameters accepted as "controlled". The authors carried out a systematic review of documents published in PubMed, Scielo and MEDLINE in the period 2012-2018, both in English and Spanish, on the arterial tension definition, evaluation and management. The guidelines agree in taking arterial tension measures in different moments for the diagnosis, but not in defining tension control. Defining tension control should include a time dimension of at least a year, and a minimal proportion of measures within the parameters recognized as non-pathological or optimal on the basis of measures taken at least every three months. Therefore, the authors suggest that an annual profile of the arterial tension parameters should be considered as a minimal requirement to evaluate arterial hypertension control.

Restoration of patient accelerating anterior teeth wear by loss of posterior support: Case report / 대한치과보철학회지

Increased anterior teeth mastication following posterior teeth loss leads to greater anterior occlusal force. It may cause greater attrition of anterior teeth, traumatic force occlusion (TFO), also often followed by antagonist extrusion and occlusal disharmony. This clinical report describes the treatment for a 67-year-old female patient diagnosed with loss of both maxillary and left mandibular posterior teeth, severe attrition of maxillary and mandibular anterior teeth and extrusion of multiple teeth. A diagnostic cast was mounted on articular in centric relation (CR) position to evaluate vertical dimension (VD) and interspace. To provide adequate space for the prosthetic reconstructions, VD was increased by 3 mm on the anterior pin. And then diagnostic wax-up was completed upon that VD. Wax-up was converted to provisional restorations and verified in the patient's mouth and the final restorations were delivered. Clinical follow up examination held 3 months after temporary restoration owing to changes in vertical dimension revealed proper function in mastication without evidence of temporo-mandibular joint (TMJ) disorders. This clinical report presents successfully restoring severe attrition case with increasing vertical dimension resulting in satisfaction in esthetics and function.

Consideraciones para el incremento de dimensión vertical de oclusión. Reporte de un caso / Considerations for the increase of occlusal vertical dimension. Report of a case

RESUMEN La dimensión vertical de oclusión (DVO) está representada por la distancia entre dos puntos, que no se pierde; sin embargo, puede verse aumentada o disminuida. Depende en buena medida de la dentición presente. Entidades patológicas como la atrición severa pueden influir su condición. La ruta clínica para llegar a la determinación de realizar un incremento de DVO es un proceso meticuloso, parte de un diagnóstico certero, cuantificación de la misma, así como la vía para realizar el procedimiento. Existen múltiples métodos para la terapéutica del incremento de DVO: dispositivos removibles o fijos. La elección del plan de tratamiento será con base en las particularidades de cada paciente. No existe tratamiento universal sino uno ideal para cada situación específica. Este caso describe las consideraciones previas al aumento de DVO en un paciente masculino de 68 años con atrición generalizada. Se evaluó la magnitud de la reducción de DVO, perfil facial y estética mediante análisis fotográfico y video; el esquema oclusal y la estructura dental presente. La literatura propone calcular con diferentes métodos el restablecimiento de la DVO; antes de elegir alguno se requiere definir y especular qué tanto se encuentra disminuida, para ello no basta un análisis estático o de simple apreciación, debe considerarse el aspecto facial, así como la dinámica mandibular. El incremento de la DVO en una sola intención, mediante restauraciones provisionales, mantenidas dentro de los parámetros de comodidad, es un excelente recurso para ejecutarla, el paciente experimenta una fase de adaptación favorable y sin complicaciones sintomáticas.

ABSTRACT Occlusal vertical dimension (OVD) is represented by the distance between two points, which is not lost, however, can be increased or decreased. Depends to a good extent on the present dentition. Pathological entities such as severe attrition can influence their condition. Clinical route to arrive at the determination to perform an increase of OVD is a meticulous process, part of a correct diagnosis, quantifi cation of the same, as well as the way to perform the procedure. There are multiple methods for this treatment: removable or fi xed devices. Choice of treatment will be based on the particularities of each patient. There is no universal treatment but an ideal for each specific situation. This case describes the considerations prior to the increase of OVD in a 68-year-old male patient with generalized attrition. Magnitude of OVD reduction, facial and aesthetic profi le was evaluated by means of photographic and video analysis; the occlusal scheme and the dental structure present. Literature consulted proposes to calculate with different methods the reestablishment of OVD, before choosing one it is necessary to defi ne and to speculate how much it is diminished, for it is not enough a static analysis or of simple appreciation must consider the facial aspect, as well as the mandibular dynamics. Increasing OVD in a single intention, through provisional restorations, maintained within the parameters of comfort, is an excellent resource to execute it, the patient undergoes a phase of favorable adaptation and without symptomatic complications.

Técnica de Alemán y Pico para la profundización del surco vestibular inferior / Alemán and Pico technique for deepening the inferior vestibular edge

A pesar de los avances en la tecnología para preservar la dentición, aún se requiere la rehabilitación del sistema masticatorio en pacientes desdentados parcial o totalmente, lo que resulta difícil y frustrante -- tanto para los afectados como para los protesistas -- si existe atrofia grave del hueso alveolar. Este problema se puede solucionar mediante una intervención quirúrgica denominada profundización del vestíbulo, dirigida a lograr el aumento de la cresta alveolar y, con ello, el soporte de las prótesis dentales. A tal efecto, en el presente trabajo se propone y describe una nueva opción terapéutica: la técnica de Alemán y Pico, para la profundización del surco vestibular inferior, la cual no es tan invasiva y resulta factible cuando no se cuenta con las condiciones necesarias para colocar implantes, ya sea por escasez de recursos materiales o por situaciones propias del paciente

In spite of the advances in technology to preserve the eruption of teeth, the rehabilitation of the masticatory system is still required in partial or totally toothless patients, what is difficult and frustrating -- either for those affected patients or for the prosthesists -- if serious atrophy of the alveolar bone exists. This problem can be solved by means of a surgical procedure denominated deepening of the vestibule directed to achieve the increase of the alveolar crest and, with it, the support of the dental prosthesis. To such an effect, this work intends and describes a new therapeutic option: the Alemán and Pico technique, for deepening of the inferior vestibular edge, which is not so invasive and it is feasible when the necessary conditions to place an implant are not available, either due to shortage of material resources or due to situations of the patients themselves

The Anti-hyperglycemic and Dipeptidyl Peptidase IV Inhibitory Activities of Bonito Dashi: Efficacy Testing in Human Subjects / 日本補完代替医療学会誌

In food science, natural ingredients that can inhibit dipeptidyl peptidase IV ( DPP IV ) may be useful for preventing diabetes mellitus. This study aimed to evaluate the effectiveness of bonito dashi having a high DPP IV inhibitory activity (IC50 ; 3049 µg/ ml) on the postprandial increase in blood glucose levels in 14 subjects. Bonito dashi (5 g) was subsequently subjected to oral glucose tolerance tests. Blood glucose levels of all subjects were measured at fasting and at 30 min after ingesting of bonito dashi or of warmed tap water as a control, and were also measured at 30, 45, 60, 75, 90, 120, and 150 min after ingestion of cooked rice. The maximum blood glucose level between 0 and 150 min after ingesting of bonito dashi was for 30 min, of warmed tap water for 45 min ). The blood glucose levels after ingestion of bonito dashi and warmed tap water were 135.6 ± 8.7 mg/ dl and 140.3 mg/ dl, respectively at 30 min ( p = 0.602 ); 135.6 ± 8.7 mg/ dl and 144.1 ± 10.7 mg/ dl, respectively at 45 min ( p = 0.057 ); 120.0 ± 4.9 mg/ dl and 136.8 ± 7.8 mg/ dl, respectively at 60 min ( p = 0.063 ); 110.0 ± 5.9 mg/ dl and 134.9 ± 6.9 mg/ dl, respectively at 75 min ( p = 0.006 ); 110.3 ± 6.8 mg/ dl and 129.3 ± 6.6 mg/ dl, respectively, at 90 min ( p = 0.036 ); 103.4 ± 4.1 mg/ dl and 118.7 ± 8.0 mg/ dl, respectively, at 120 min ( p = 0.091 ); 91.5 ± 3.8 mg/ dl and 102.3 ± 5.9 mg/ dl, respectively, at 150 min ( p = 0.232 ). The area under the curve for blood glucose levels after ingestion of bonito dashi and warmed tap water was 4753.1 ± 439.7 mg/ dl ×min and 6879.4 ± 728.1 mg/ dl ×min, respectively ( p = 0.005 ). Postprandial increase in blood glucose levels was lower in subjects ingestion of bonito dashi than in those ingestion of the warmed tap water. No serious adverse events related to ingestion of bonito dashi were observed. Our findings suggested that the ingestion of bonito dashi (5 g) suppressed postprandial increase in blood glucose levels in our subjects.

Impactos da ocupação urbana na permeabilidade do solo: o caso de uma área de urbanização consolidada em Campina Grande - PB / Impacts of the disordered land occupancy: a study about an urban consolidated area in Campina Grande - PB

RESUMO A ocupação urbana intensa e não planejada acarreta problemas diretos à população. Um desses problemas é a diminuição do índice de permeabilidade do solo gerada pela pavimentação crescente que sempre acompanha o desenvolvimento urbano de uma região. Em consequência, o sistema de drenagem pode sofrer sobrecargas uma vez que a capacidade de infiltração do solo é alterada e a pavimentação aumenta a velocidade de escoamento e as vazões de pico. Este trabalho apresenta uma análise integrada da dinâmica do uso do solo ao longo de 32 anos e do comportamento do sistema de microdrenagem urbana para o cenário atual de ocupação dos bairros Catolé e Sandra Cavalcante, em Campina Grande (PB). Verifica-se a deficiência do sistema de microdrenagem em não acompanhar o acelerado crescimento da região, acarretando em pontos de alagamento que geram prejuízos e desconfortos à população em períodos de chuva mais concentrada.

ABSTRACT The intense and unplanned urban occupation entails direct problems to the population. One of these problems is the decrease in the permeability index of soil generated by increasing paving that always accompanies the urban development of a region. As a result, the drainage system may experience overloads, once the infiltration capacity of the soil is changed and the paving increases the flow rate and the peak flows. This paper presents an integrated analysis of land use dynamics over the course of 32 years and the behavior of the urban micro-drainage system to the current scenario of occupation of Catolé and Sandra Cavalcante neighborhoods, in Campina Grande, PB. It verifies the disability of the micro-drainage system to accompany the accelerated growth of the region, leading in points of flooding that generate losses and discomforts to the population in more concentrated rain periods.

Colocación de implantes dentales en maxilar atrófico con técnica de cresta dividida y expansión del reborde / Placement of dental implants in atrophic jaw with divided crest and ridge expansion technique

RESUMEN: Este reporte de caso describe la colocación de implantes dentales en un paciente con antecedente del hábito de fumar y que presenta periodontitis crónica severa y atrofia maxilar con deficiencia de volumen óseo en sentido horizontal. Simultáneamente a la colocación de implantes se utilizó la técnica de cresta dividida, expansión del reborde y colocación de injerto óseo bovino. Después de seis meses, se observó la oseointegración de todos los implantes y se procedió a la confección de la prótesis implantosoportada de tipo híbrida (anclaje óseo completo). Finalmente, se realizó el seguimiento del caso durante un periodo de 18 meses sin observar complicaciones y con un resultado funcional y estético satisfactorio para el paciente.

ABSTRACT: The present case report describes placement of tooth implants in a patient with history of smoking, exhibiting severe, chronic periodontitis and maxillary atrophy with horizontal bone volume deficiency. Simultaneously to implant placement, the technique of divided crest, ridge expansion and bovine bone graft placement was used. After six months, bone integration of all implants was observed and a hybrid, implant-supported prosthesis was manufactured (full bone anchorage). Finally the case was followed for 18 months without observing any complications, and with satisfactory functional and esthetic results for the patient.

Prevalence of myopia and increase trend in children and adolescents aged 7-18 years in Han ethnic group in China, 2005-2014 / 中华流行病学杂志

Objective To understand and evaluate the prevalence of myopia and its trend in children and adolescents aged 7-18 years in Han ethnic group in China from 2005 to 2014,and provide evidence for the prevention of myopia.Methods The data of 2005,2010 and 2014 Chinese National Students Constitution and Health Surveys were collected.The children and adolescents with complete detection data of binoculus were selected as study subjects.The sample size of three studies were 233 108,215 319 and 212 743,respectively.The method of curve fitting was used to simulate the myopia detection increase model and analyze the gender and area specific myopia detection increase trends and characteristics from 2005 to 2014.Results The overall myopia detection rate increased gradually in the children and adolescents aged 7 to 18,which was 47.5％ in 2005,55.5％ in 2010 and 57.1％ in 2014,respectively.The increase slowed in 2014.A "parabola" shape of myopia detection increase rate was observed.Myopia detection rate increased with age before puberty and decreased with age after puberty gradually.A "cross phenomenon" of myopia detection increase was observed in boys and girls between urban and rural areas.The increase of myopia detection was mainly in urban students before puberty and in rural students after puberty.The age of myopia prevalence peak has become earlier constantly in children and adolescents aged 7-18 years from 2005 to 2014,which was 13 years old in 2005,12 years old in 2010 and 11 years old in 2014.The increase rate was about 7％.During 2005-2014,the increase rate of myopia detection gradually increased in younger students and tended to zero in older students.Conclusion The detection rate of myopia was still high in children and adolescents in China.The age of myopia prevalence peak has become earlier gradually.

Metastatic follicular thyroid carcinoma as a cause of low serum thyroxine with a normal thyroid stimulating hormone level / Journal of the ASEAN Federation of Endocrine Societies

@#Thyroid function is usually normal in differentiated thyroid carcinoma. We describe a case of a female patient who had metastatic follicular thyroid carcinoma (FTC) to the spine and lungs, who was clinically euthyroid but had very low free tetraiodothyronine (fT4) and normal thyroid stimulating hormone (TSH). Free triiodothyronine (fT3) and total T3 (TT3) were normal. Levothyroxine treatment increased fT4 marginally but caused a two- to three-fold rise in fT3 and TT3 along with suppressed TSH. This is likely due to hyperconversion of T4 to T3 from elevation in D2 deiodinase activity in the tumor. This phenomenon has been reported to occur in about 20% of metastatic FTC.

Prevalence of myopia and increase trend in children and adolescents aged 7-18 years in Han ethnic group in China, 2005-2014 / 中华流行病学杂志

Objective To understand and evaluate the prevalence of myopia and its trend in children and adolescents aged 7-18 years in Han ethnic group in China from 2005 to 2014,and provide evidence for the prevention of myopia.Methods The data of 2005,2010 and 2014 Chinese National Students Constitution and Health Surveys were collected.The children and adolescents with complete detection data of binoculus were selected as study subjects.The sample size of three studies were 233 108,215 319 and 212 743,respectively.The method of curve fitting was used to simulate the myopia detection increase model and analyze the gender and area specific myopia detection increase trends and characteristics from 2005 to 2014.Results The overall myopia detection rate increased gradually in the children and adolescents aged 7 to 18,which was 47.5％ in 2005,55.5％ in 2010 and 57.1％ in 2014,respectively.The increase slowed in 2014.A "parabola" shape of myopia detection increase rate was observed.Myopia detection rate increased with age before puberty and decreased with age after puberty gradually.A "cross phenomenon" of myopia detection increase was observed in boys and girls between urban and rural areas.The increase of myopia detection was mainly in urban students before puberty and in rural students after puberty.The age of myopia prevalence peak has become earlier constantly in children and adolescents aged 7-18 years from 2005 to 2014,which was 13 years old in 2005,12 years old in 2010 and 11 years old in 2014.The increase rate was about 7％.During 2005-2014,the increase rate of myopia detection gradually increased in younger students and tended to zero in older students.Conclusion The detection rate of myopia was still high in children and adolescents in China.The age of myopia prevalence peak has become earlier gradually.

Metastatic Follicular Thyroid Carcinoma as a cause of low serum thyroxine with a Normal Thyroid stimulating hormone level / Journal of the ASEAN Federation of Endocrine Societies

@#Thyroid function is usually normal in differentiated thyroid carcinoma. We describe a case of a female patient who had metastatic follicular thyroid carcinoma (FTC) to the spine and lungs, who was clinically euthyroid but had very low free tetraiodothyronine (fT4) and normal thyroid stimulating hormone (TSH). Free triiodothyronine (fT3) and total T3 (TT3) were normal. Levothyroxine treatment increased fT4 marginally but caused a two- to three-fold rise in fT3 and TT3 along with suppressed TSH. This is likely due to hyperconversion of T4 to T3 from elevation in D2 deiodinase activity in the tumor. This phenomenon has been reported to occur in about 20% of metastatic FTC.

Adaptabilidade e estabilidade e a produtividade de grãos em cultivares de feijão preto recomendadas no Brasil nas últimas cinco décadas / Adaptability and stability and grain yield of black common bean cultivars used in Brazil in the last five decades

RESUMO:O objetivo deste trabalho foi estudar os parâmetros de adaptabilidade e estabilidade fenotípica e avaliar o incremento na produtividade de grãos em genótipos de feijão preto, desenvolvidos pelos programas brasileiros de melhoramento genético entre os anos de 1960 a 2013. Os experimentos foram realizados considerando 38 cultivares e duas linhagens em quatro ambientes (Coimbra e Viçosa nas safras da seca e de inverno de 2013), usando um delineamento em blocos casualizados com três repetições. Os resultados evidenciaram incremento efetivo na produtividade de grãos, proporcionado pela recomendação de novas cultivares pelos programas de melhoramento de feijão do Brasil nas últimas cinco décadas. Além disso, a análise da interação GxA indicou que as cultivares recomendadas após o ano de 2005 foram as que apresentaram conjuntamente altas produtividades de grãos, ampla adaptabilidade e alta previsibilidade de comportamento.

ABSTRACT:The objective of this research was to study the parameters of adaptability and phenotypic stability and estimate the increase in grain yield in black common bean genotypes developed by brazilian breeding programs between the years 1960-2013. The experiments were carried out considering 38 cultivars and two lines in four different environments (Coimbra and Viçosa cities, and dry and winter seasons of 2013 year) by using a randomized block design with three replications. Results showed an effective increasing of the grain yield provided by the recommendation of new cultivars from different Brazilian breeding programs in the past five decades. In addition, the GxE analysis interaction indicated that cultivars recommended after the year 2005 were those with high average grain yield, wide adaptability and high predictability.

BIOLOGÍA DEL ÁFIDO NEGRO (Aphis craccivora: APHIDIDAE) SOBRE FRÍJOL CAUPI (Vigna unguiculata, FABACEAE) / Biology of Black Aphid (Aphis Craccivora: Aphididae) on Cowpea(Vigna Unguiculata, Fabaceae)

Este trabajo describe los parámetros biológicos y poblacionales del pulgón negro, Aphis craccivora Koch, sobre fríjol caupí (Vigna unguiculata (L. Walp.)), bajo condiciones de laboratorio. Los insectos se criaron sobre plántulas individualizadas a una temperatura promedio de 28 °C, humedad relativa de 70 % y fotoperiodo de 12 horas. Los parámetros medidos fueron periodo ninfal, fecundidad, supervivencia, periodo pre-reproductivo y aspectos relativos a la tasa de crecimiento del áfido. La tasa reproductiva neta R (0) fue 66,00, la tasa intrínseca de crecimiento del áfido (r m) fue 0,51, el tiempo de duplicación de la población (TD) fue 2,3. Se analizaron las curvas de supervivencia (lx), fecundidad (mx), la duración del período ninfal y reproductivo del áfido. Los resultados difieren de los realizados en otras variedades de fríjol caupí, evidenciándose la susceptibilidad de la variedad criolla usada por los agricultores en la costa Caribe colombiana.

This research describes the population and biological parameters of the black aphid (Aphis craccivora Koch) on cowpea bean (Vigna unguiculata (L. Walp.)), under laboratory conditions. The insects were raised on individualized seedlings in an average temperature of 28 °C, at 70 % relative humidity during a photoperiod of 12 hours. The parameters measured were the nymphal period, fecundity, longevity, pre-reproductive period and aspects of aphid growth rate. The net reproductive rate R (0) was 66.00, the intrinsic g rate of increase of the aphid (rm) was 0.51, and the population doubling time (TD) was 2.3. Survival curves (lx), fecundity (mx), the duration of nymphal and the reproductive period of the aphid were analyzed. The results differ from those found in other varieties of cowpea beans, demonstrating the susceptibility of the native variety used by farmers in the Colombian Caribbean coast.