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Aim To evaluate the antichlamydial activity of our previously synthesized sixteen 1, 2-disubstituted pyrroles in vitro, providing candidate for the development of novel agents against Chlamydia. Methods Firstly, the inhibitory effect of compounds on the generation of infectious progeny EBs at different concentrations was analyzed for Chlamydia trachomatis L2 (Ct L2), C. muridarum (Nigg II strain, known as MoPn) and C. pneumonia (Cpn AR39). The IC
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Objective To compare the traditional Chinese medicine enema and routine enema in the period of gastrointestinal dysfunction in patients with severe burn infection the clinical effect of treatment. Methods The control group weakened symptoms on gastrointestinal peristalsis began to appear fasting, gastrointestinal decompression, anal exhaust, saline enema, parenteral nutrition, antibiotic treatment. On the basis of routine treatment in the treatment group the enema for Chinese medicine prescription. Results The curative effect in the treatment group after enema 83.3%(30/36) compared with the control group 41.70% (15/36) had significant difference (P<0.05). At the time of borborygmus, abdominal distension disappeared time, anus Exhaust time, the treatment group were (7.0±0.8)d, (3.4±0.9)d, (7.3±0.8)d, the control group were (12.6±1.8)d, (7.1±1.2)d, (13.4±1.9)d, two sets of data were compared with statistical difference (P<0.05). Conclusion The traditional Chinese medicine enema for large surface gastrointestinal dysfunction during infection deposition burn patients is rapid, safe and reliable, convenient administration, significant curative effect on gastrointestinal functions in patients with motility.
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Objective To compare the traditional Chinese medicine enema and routine enema in the period of gastrointestinal dysfunction in patients with severe burn infection the clinical effect of treatment. Methods The control group weakened symptoms on gastrointestinal peristalsis began to appear fasting, gastrointestinal decompression, anal exhaust, saline enema, parenteral nutrition, antibiotic treatment. On the basis of routine treatment in the treatment group the enema for Chinese medicine prescription. Results The curative effect in the treatment group after enema 83.3%(30/36) compared with the control group 41.70% (15/36) had significant difference (P<0.05). At the time of borborygmus, abdominal distension disappeared time, anus Exhaust time, the treatment group were (7.0±0.8)d, (3.4±0.9)d, (7.3±0.8)d, the control group were (12.6±1.8)d, (7.1±1.2)d, (13.4±1.9)d, two sets of data were compared with statistical difference (P<0.05). Conclusion The traditional Chinese medicine enema for large surface gastrointestinal dysfunction during infection deposition burn patients is rapid, safe and reliable, convenient administration, significant curative effect on gastrointestinal functions in patients with motility.