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Based on WANG Xugao's “thirty methods of treating the liver”, it is believed that the occurrence and development of childhood tic disorders follow the dynamic progression from liver qi disease to liver fire disease and then liver wind disease. The basic pathogenesis of three stages are characterized by binding constraint of liver qi, liver fire hyperactivity, and internal stirring of liver wind. Moreover, liver-blood deficiency and stagnation, and malnutrition of liver yin as the main point in terms of the imbalance of liver qi, blood, yin, and yang should be considered, as well as the imbalance relationship of the five zang organs such as the involvement of other organs and the gradually reach of the other organs. Guided by the principles of “thirty methods of treating the liver”, the treatment of tic disorders in liver qi stage should focus on soothing the liver and rectifying qi, soothing the liver and unblocking the collaterals, using Xiaochaihu Decoction (小柴胡汤) and Sini Powder (四逆散). The treatment of tic disorders in liver fire stage involves clearing, draining and resolving liver heat, using Longdan Xiegan Decoction (龙胆泻肝汤), Xieqing Pill (泻青丸), Danggui Longhui Pill (当归龙荟丸), and Huagan Decoction (化肝煎). The treatment of tic disorders in liver wind stage involves extinguishing wind and subduing yang, using Lingjiao Gouteng Decoction (羚角钩藤汤) and Liuwei Dihuang Pill (六味地黄丸). Throughout the treatment process, attention should be paid to harmonizing the liver's qi, blood, yin, and yang, as well as addressing the pathology of other organs.
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Objective To explore Professor Wu Liqun's medication law for treating tic disorders in children.Methods Medical records of tic disorders children treated by Professor Wu Liqun from September 2016 to October 2022 were collected,and a database was established.SPSS Statistics 23 was used for frequency statistics,and Liquorice software was used for multi-scale backbone network analysis and multi-layer core network analysis to summarize the medication law.Results Totally 709 medical records were included,involving 834 prescriptions and 203 kinds of Chinese materia medica.The drug categories were mostly tonic drugs,heat-clearing drugs,and liver-pacifying and wind-relieving drugs.The properties of the drugs were mainly warming,cold,and mild,and the meridians were mostly in the lung,liver,and spleen meridians.Complex network analysis showed that the core prescription consisted of 20 kinds of Chinese materia medica,such as Angelicae Sinensis Radix,Paeoniae Radix Alba,Chuanxiong Rhizoma,Codonopsis Radix,and 30 groups of commonly used medicine pairs and commonly used medicines with different symptoms and commodities were obtained.Conclusion Professor Wu Liqun's treatment for tic disorders in children focuses on treating"liver wind",evacuating external wind to cut off the course of the disease,soothing the liver and subduing yang to extinguish internal wind,paying attention to regulating liver qi,nourishing yin and soothing the liver,nourishing blood and extinguishing wind.
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The chief physician MEI Da-zhao uses TCM for treatment of children with incurable diseases, which is accurate in syndrome differentiation and with obvious efficacy. This article selected 4 cases (liver wind syndrome, convulsion disease, cough, palpitations), and carried out in depth analysis.
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[Objective] To conclude the clinical experience of vertigo treatment using“wind tranquilizing method”by Pro. Lian Jianwei. [Method] Through analyzing clinical cases, generalizing the major syndrome, basic formula and formula modification of “wind tranquilizing method”used by Pro. Lian Jianwei to treat vertigo. [Result] The major pathogenesis of vertigo is wind, fire, phlegm, blood stasis and deficiency of blood. Pathological change of vertigo is in liver and so the treatment requires the tranquilizing of the liver-wind. Pro. Lian Jianwei is good at using“wind tranquilizing method”to cure vertigo caused by liver-wind stirring internal y. The formula of“wind tranquilizing method”takes into account the nature of vertigo and the physiological characteristics of the liver. He is also good at modifying the formula according to the patient conditions. [Conclusion] Pro. Lian Jianwei is good at prescrib-ing formula according to principles and treating methods. He also has deep understanding for the characteristic of vertigo and liver. Therefore the formula of his“wind tranquilizing method”has clinical value in terms of vertigo treatment.
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Although the treatment of Parkinson's disease is well established, side effects and weaning effects in the long term are a problem. In this context, it is reasonable to establish an alternative medicine for Parkinson's disease. Hange-byakujutsu-tenma-to in traditional Japanese medicine (Kampo) is similar to Teishingan, a formula for Parkinson's disease in traditional Chinese medicine, in that both formulas contain tenma and qi-supplying agents. We therefore administered Hange-byakujutsu-tenma-to (TJ-37, Tsumura, Tokyo) to a 77-year-old woman with Parkinson's disease. After taking Hange-byakujutsu-tenma-to, her symptoms of rigidity of the upper limbs, frozen gait, propulsion and retropulsion improved. These results suggest that Hange-byakujutsu-tenma-to is useful for treating Parkinson's disease.
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Objective:To investigate the clinical effects and main pharmacological actions of Pingantongluo Granules (Radix Paeoniae Alba, Rhizoma Gastrodiae, Radix Salviae Miltiorrhizae, Rhizoma Chuanxiong, Concha Haliotidis, etc.) for migraine with liver wind and blood stasis symptom. Methods: Randomized controlled trail, double blind and double dummy method were applied. Yuntongding Tablets was used as a control drug in clinical investigation and Routunding Tablets as a control drug in pharmacological experiment study. Results: The total effective rates of the treatment group and the control group were 95.0% and 83.3% for migraine and 80.0% and 61.6% for the liver wind and blood stasis symptom, respectively. Pinggantongluo Granules began to act on migraine in ( 11.75 ? 6.70 )h, and the control drug did in ( 18.30 ? 8.22 )h. There were a significant difference between two groups ( P