Magnésio mononuclear em hipertensos idosos tratados com tiazídico / Mononuclear magnesium in aged hypertensive patients treated with thiazide

Purpose­To study mononuclear magnesium and serum cations (Na, K and Mg) in elderly hypertensive patients treated with hydrochlorothiazide during 90 days. Patients and Methods­ 15 elderly hypertensive patients treated with hydrochlorothiazide, 25 mg/day or placebo. A method of freezing produced total Iysis of the cells; Mg was measured by atomic spectrophotometry. Results­No differences were noted in mononuclear or serum magnesium in the thiazide or placebo treated patients, and the diuretic produced significant decreases in supine systolic and diastolic blood pressure. Conclusion­Magnesium supplementation does not seem essencial in most patients in this conditions