RESUMEN
In recent years， the field of network pharmacology （NP） has developed rapidly， but the flawed and routine workflow has seriously affected the scientificity and reliability of NP analysis results. For complex diseases caused by environmental and genetic factors， symptomatic treatment or drugs targeting a single pathophysiological process cannot prevent or delay the progression of the disease， so the drug development fails or withdraws from the market. Therefore， there is an urgent need to develop new ideas for NP analysis that combines multiple pathophysiological processes. The key pathophysiological process is an important and complete set of pathological changes in the process of the occurrence， development， and outcome of the disease， which represents the current comprehensive and profound understanding of the nature of the disease. In order to improve the quality of NP research and promote the healthy development of the NP field， this paper proposes a new idea of NP analysis based on key pathophysiological processes. Based on the long-term clinical practice of traditional Chinese medicine and the key pathophysiological process of the disease， the method comprehensively analyzes the pharmacological mechanism and active ingredients of traditional Chinese medicine compound from the perspective of key pathophysiological process， which increases the scientifically， reliability， and repeatability of the analysis results. This paper takes Alzheimer's disease （AD） as an example to illustrate the necessity， feasibility， main workflow， advantages， and disadvantages of this method， and it is expected to screen disease-modifying drugs that prevent or reverse the course of the disease and promote the clinical transformation of research results.
RESUMEN
Currently, researches on traditional Chinese medicine ethics should hold the responsibility to carry forward and inherit the excellent traditional culture, as well to explore the ethics of traditional culture, contemplate the reality, advance with the times, and then to perfect the community. Therefore, we could exploit the following paths:Firstly, contemplating the reality and combing traditional Chinese medicine ethics so as to construct the tra-ditional Chinese medicine ethics system in the modern context. Secondly, tracing problems and strengthening the practice research of traditional Chinese medicine ethics so as to fulfill the statecraft, and being intimate to people. Thirdly, keeping the position of the colleges and universities of traditional Chinese medicine and promoting the in-heritance of traditional Chinese medicine ethics.
RESUMEN
To clarify the meaning, role and significance of the new idea of the modern basic theory of traditional chinese medicine, We clarified its origin and evolution starting from the basic concept of idea in this paper, re-vealed the basic connotation and relationship of ideas, scientific ideas, Chinese medicine ideas, and the new ideas of the modern basic theory of traditional Chinese medicine, and tried to give proper definitions; summarized three roles of scientific ideas. According to this basis, we demonstrated the new idea is the scientific ideas with core spirit run-ning through rational questioning, scientific testing, research and conclusion being accepted three-point line cen-tral interlocking; and have three roles changing the theory of traditional chinese medicine, guiding the innovative research on chinese medicine and elevating the scholars' thoughts. We proposed yin and yang to refer to the hypothesis of body's physiology and pathology and prevention and treatment effects, given an empirical analysis a feasible way of medicine and philosophy separation and yin and yang turning to medicine; displayed the guidance of new idea and to show the scientific connotation and scientific value of the theory of traditional Chinese medicine.
RESUMEN
As a doctor,the beneficene,responsibility,sympathy is the base,considering people,serving people,and summarizing people is the essence,bringing forth new ideas is the soul.The essay expound the point "Morality is important to be a doctor and bringing forth new ideas is also precious" from the 3 aspects.