A Case of Gallbladder Perforation Complicated by Acalculous Cholecystitis due to Non-Typhoidal Salmonella / 대한내과학회지

Salmonella infections can cause a variety of diseases, but acute acalculous cholecystitis complicated by gallbladder perforation occurs very rarely in adults. Here, we report a case of acute acalculous cholecystitis with gallbladder perforation after non-typhoidal group D Salmonella infection. A 71-year-old man was admitted with fever, chills, and watery diarrhea. Blood cultures taken on admission were positive for non-typhoidal group D Salmonella. The patient subsequently developed acute acalculous cholecystitis, and abdominal ultrasound and computed tomography revealed gallbladder perforation. Because of other medical problems, cholecystectomy could not be performed. The patient's symptoms and signs were not resolved, even after parenteral antibiotic injection and percutaneous cholecystostomy. Despite meticulous supportive care, the patient died after progression to multiple organ dysfunction.

Salmonella wien from gastroenteritis cases encountered in Mangalore, India : A report of 10 cases and review of the literature.

Ten cases of gastroenteritis due to S. Wien were reported from a tertiary care hospital in Mangalore, in the month of April 2008. Biochemically, it resembles S. Paratyphi B or S. Typhimurium. Serotyping was done at the Central Research Institute, Kasauli, to confirm the identity. The food source is more likely to be chicken or some poultry products. All the 10 cases recovered with symptomatic treatment including antimicrobials like fluoroquinolones. To the best of our knowledge, no documented report is available from India regarding the prevalence of this organism in humans.

The Serogroup and Antimicrobial Resistance of Salmonella spp. Isolated from the Clinical Specimens During 6 years in a Tertiary University Hospital / 대한임상미생물학회지

BACKGROUND: Recently, non-typhoidal salmonellosis is increasing and it constituted over 90% of total salmonellosis in 1990s. The antimicrobial resistance of non-typhoidal Salmonella gets higher. So we described the change of serogroup and antimicrobial resistance of Salmonella isolated from clinical specimens in Ewha Womans University Mokdong Hospital during 6 years. METHODS: Clinical specimens were submitted from 1997 to 2002. Stool cultures were inoculated onto MacConkey (MAC) agar and Salmonella-Shigella (SS) agar and into Selenite F (SF) enrichment broth. Identification of Salmonella were performed by Vitek GNI card (BioMerieux, Marcy-I'Eltoile, France) and serotyping were done. Antimicrobial resistance test were performed by Vitek GNS card (BioMerieux, Marcy-I'Eltoile, France). RESULTS: From 1997 to 2002, 594 strains of Salmonella were isolated. Non-typhoidal Salmonella and Salmonella typhi constituted 94.4% and 5.6%. Non-typhoidal Salmonella were mainly composed of group B (21.5%) and group D (48.0%), but in 2002, group C (12.4%) and group E (27.9%) were increased in number. The antimicrobial resistance rate of non-typhpoidal Salmonella were 28% to ampicillin, 4.1% to SXT, 0.2% to ciprofloxacin and 0.7% to ceftriaxone. The animicrobial resistance rate of group B and D Salmonella showed 37.5% and 32.6% to ampicillin, 7.8% and 4.2% to SXT, respectively. CONCLUSIONS: Serogroup B and D Salmonella were most frequently isolated, but group C and E Salmonella have been increased in 2002. Antimicrobial resistance of group B and D Salmonella were higher than other serogroups and have been increased year by year.