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Objective:To analyze the efficacy and the adverse reactions of conventional treatment-failed advanced refractory ovarian cancer cases after treatment with apatinib.Methods:Six patients enrolled in the Second Hospital of Tianjin Medical University from June 2015 to October 2015 received treatment with apatinib. Treatment efficacy was evaluated by imaging and analysis of tumor markers,including CA125,CEA,and NSE.Results:The age range of the six patients was 48-71 years(median:55 years).Their histopath-ological subtypes included poorly differentiated serous cystadenocarcinoma(4/6),borderline papillary adenoma(1/6),and clear cell carcinoma(1/6).Clinical evaluation of patients revealed no cases with complete remission,two cases with partial response,one case with stable disease,and three cases with progressive disease.The objective response rate was 33%(2/6)and the disease control rate was 50%(3/6).In all patients,the main side effects were hypertension and hand-foot syndrome,which were controlled.Conclusions:The treatment of conventional treatment-failed advanced refractory ovarian cancer with apatinib has better exact effects,and medical toxicity can be controlled.In the future,to seek more effective treatment strategies,the mechanism of apatinib in the treatment of ad-vanced ovarian cancer should be further explored.
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Objective To analyze CT findings of misdiagnosed or missed ovarian cystic mature teratomas to improve the diagnosis.Methods CT images of 145 cases were retrospectively reviewed.Among them,29 cases of ovarian cystic teratomas were misdiagnosed or missed.Results Five cases of struma ovarii were diagnosed as cyctadenocarcinoma,7 cases of cystic mature teratoma were misdiagnosed as cyst in 2 cases,ovarian endometrial cyst in 2 cases and cystadenoma in 3 cases.17 cases of cystic mature teratoma weremissed diagnosis, in which there were torsion in 7 cases,infection in 4 cases,bleeding in 3 cases,endometriosis cyst,serous cystadenoma and tuberculosis in 1 case respectively.Conclusion Understanding the atypical misdiagnosed or missed CT manifestation of ovarian cystic mature teratomas permits a more specific and accurate diagnosis,which may be useful for preoperative diagnosis.
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Pelvic pain syndrome or pelvic congestion syndrome, with no apparent organic cause, is a common gynecologicaldisorder. Ovarian varix, one of the causes of this syndrome, presents a difficult diagnostic and therapeuticproblem, though surgical ligation of the ovarian vein is an effective method of treatment. Although ovarian veinembolization has been recently developed as a useful alternative, no previous reports have described thisprocedure in Korea. We report a case of pelvic pain syndrome successully treated by ovarian vein embolization.