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1.
Acta Pharmaceutica Sinica ; (12): 1749-1756, 2021.
Artículo en Chino | WPRIM | ID: wpr-887019

RESUMEN

This paper reviews modern science and technology with regard to traditional Chinese medicine (TCM) research methods, quality control, and discusses the establishment and improvement of the evaluation system for TCM, focusing on the following issues: 1) How to incorporate the efficacy of TCM in the overall evaluation of TCM quality; 2) how to quantify the efficacy and properties of TCM; 3) how to understand the correlation between the efficacy and properties of TCM and its application; 4) how to reflect the specificity of the effective components in the overall evaluation of TCM quality; and 5) how to reflect the quality value transfer of effective components in the whole process of production and metabolism in vivo to the overall evaluation of TCM quality. The overall quality evaluation of TCM needs to better reflect its clinically safety and effectiveness. It is suggested to establish a clinical quality assessment method based on the content of the chemical components of TCM to explore and establish an overall evaluation method of TCM quality that reflects the efficacy of TCM and conforms with clinical practice.

2.
China Journal of Chinese Materia Medica ; (24): 978-983, 2020.
Artículo en Chino | WPRIM | ID: wpr-1008461

RESUMEN

By consulting the literatures of foreign plant medicine Echinacea purpurea at home and abroad, this paper discusses the property and function of E. purpurea from the point of view of traditional Chinese medicine theory, so as to realize "herbalization", provide the theoretical basis of traditional Chinese medicine for the correct clinical application and rational compatibility of E. purpurea, and broaden the scope and varieties of clinical selection of traditional Chinese medicine. Relevant literatures of E. purpurea were selected from PubMed and CNKI databases and classified based on clinical application, chemical composition, pharmacological action, toxic and side effects. Those with a high reliability were screened out, including 313 articles in English and 46 in Chinese. Finally, the basic theory of traditional Chinese medicine was analyzed. In our view, E. purpurea features pungent and bitter tastes and a cold nature, and enters lung, spleen, heart meridians, with effects in evacuating wind-heat, clearing heat and detoxifying, invigorating Qi, strengthening body resistance, and treating wind-heat cold, sore throat swelling pain, cough, heat toxin stagnation, sore carbuncle swelling toxin, red swelling heat pain, body deficiency and multiple diseases, fatigue burnout. This paper analyzes the research literatures of E. purpurea, "herbalize" it, endows it with the property and function of traditional Chinese medicine, lays the foundation for further animal experiment and clinical research, and provides scientific theoretical guidance for the better application of E. purpurea in clinic and its proper compatibility and rational application. This research model will also provide reference for further studies of "traditional Chinese medicine" of foreign plant drugs, enrich traditional Chinese medicine resources, and promote the healthy and sustainable development of traditional Chinese medicine.


Asunto(s)
Humanos , Medicamentos Herbarios Chinos , Echinacea/química , Medicina Tradicional China , Meridianos , Plantas Medicinales/química
3.
China Journal of Chinese Materia Medica ; (24): 3481-3488, 2020.
Artículo en Chino | WPRIM | ID: wpr-828422

RESUMEN

In this article, the foreign and domestic literature on alien plant medicine Cynara scolymus was reviewed to explore its properties and functions in traditional Chinese medicine theory, and provide theoretical basis for clinical application and reasonable compatibility. Based on the literature databases of PubMed, Web of Science, Embase, the Cochrane Library, CNKI, VIP and Sinomed, the articles with high reliability related to C. scolymus were screened out and the obtained articles were systematically classified according to clinical application, chemical compositions, pharmacological action, toxic and side effects, etc. In the analysis with traditional Chinese medicine theory, it is concluded that: C. scolymus tastes bitter and slightly cold, attributing to spleen, stomach, liver and gall meridians. It has the functions of eliminating accumulation and guiding stagnation, regulating Qi-flowing for harmonizing stomach, clearing away dampness and heat, resolving turbidity and lowering blood lipids. It can be used for the treatment of dyspepsia, diet reduction, vomiting, nausea, abdominal distention, hypochondriac pain, jaundice, hyperlipidemia, etc. Through the analysis and research of the relevant literature on C. scolymus, the properties and functions of the drug were clarified, which could provide a theoretical basis for further animal experiments and clinical research. The research model of "traditional Chinese medicine theory" for alien plant medicines can provide reference for the introduction and research of botanical drugs around the world, which can greatly enrich Chinese medicine resources and is of great significance for promoting the sustainable development of traditional Chinese medicine.


Asunto(s)
Animales , Cynara scolymus , Medicamentos Herbarios Chinos , Medicina Tradicional China , Meridianos , Reproducibilidad de los Resultados
4.
China Pharmacy ; (12)2005.
Artículo en Chino | WPRIM | ID: wpr-528301

RESUMEN

OBJECTIVE:To explore a new way for the investigating of processing impact on the property of the traditional Chinese medicine(TCM)so as to provide new ideas and methods for the scientific research on TCM.METHODS:Ideas of in?vestigating the impact of processing on the property of TCM by using the method of biothermodynamics and setting up a new method system of research and evaluation on TCM were put forward through reviewing and analyzing the status quo and problems of processing impact on property of TCM and the commonness and characteristics between TCM and biothermody?natics.RESULTS&CONCLUSIONS:Theoretically and practically,it is feasible to investigate processing impact on the property of TCM by using biothermodynamic ideas and methods,and it is expected that which can serve as a new visual angle and technical platform in the modernization study of TCM.

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