RESUMEN
Purpose: This randomized, controlled, blinded study evaluates the efficacy of intense pulsed light (IPL) therapy with low?level light therapy (LLLT) in the treatment of meibomian gland dysfunction (MGD) and evaporative dry eye (EDE) compared to a control group. Methods: Hundred patients with MGD and EDE were randomized into control (50 subjects, 100 eyes) and study group (50 subjects, 100 eyes). The study group underwent three sittings of IPL with LLLT 15 days apart and were followed up 1 month and 2 months after the last treatment sitting. The control group underwent sham treatment and was followed up at the same intervals. The patients were evaluated at baseline and 1 month and 3 months (post 1st treatment) for dry eye. Schirmer's test and tear breakup time (TBUT), OSDI, meibomian gland expression, and meibography. Results: The study group showed significant improvement in OSDI scores (P < 0.0001) compared to the control group and a significant improvement in TBUT (P < 0.005) compared to the control group. There was no change in schirmer's test and an improvement in the meibomian gland expression but not significant. Conclusion: The results show that a combined therapy of IPL with LLT is effective in treating MGD with EDE compared to controls, and repeated treatment sessions have a cumulative effect on the disease outcomes
RESUMEN
Objective To compare effect of swaddle bathing and tub bathing on neonatal behavior state, and improve the safety and comfort of newborn infants. Methods This was a prospective non-randomized control study. From February 2016 to September 2017, a total of 110 neonates were divided into swaddle bathing group or tub bathing group, each group including 55 cases. Neonates in swaddle bathing group received swaddle bathing after discharge, while neonates in tub bathing group received tub bathing. Behavior state in the process of bathing and temperature before and after bathing were compared. Results In swaddle bathing group, 85.5％ (47/55) of neonates kept quiet during the bathing process, which was significantly higher than 56.4％(31/55) in the tub bathing group (χ2=11.282, P<0.01). 30.9％(17/55) of neonates in swaddle group were crying, significantly lower than 50.9％ (28/55) in tub bathing group (χ2=4.550, P<0.05). Duration of neonatal grasp reflex, crying time (seconds), and neonatal body temperature after bathing was (2.3±0.4) points,2(0,7)s and (36.49±0.02)℃in swaddle bathing group, and (7.9±0.5) points, 6 (5,10) s and (36.38±0.03)℃in tub bathing group, and the difference was significant(t=4.366, 2.910, Z=3.534, P<0.01). Conclusions Swaddle bathing can promote neonatal behavior state in the process of bathing and reduce neonatal the feeling of fear. Moreover, it could help keep warm more effectively.
RESUMEN
Objective To observe the clinical effect of treating atlanto-axial subluxation by manipulative reduction therapy. Methods 128 patients with atlanto-axial subluxation confirmed by cervical plain X ray were randomized into two groups: 64 in the treatment group treated by manipulative reduction therapy, and 64 in the control group treated by the routine cervical traction. The clinical effect was evaluated by both clinical and X-ray confirmation. Results The X-ray study showed that after treatment the reconstruction of excursion in odontoid process in the treatment group was better than that in the control group significantly (P<0.01). The improvement of vertebra basal artery blood flow in the treatment group was also better than that in the control group significantly (P<0.05). The total effective rate of the treatment group was 95.3%, while the control group was 78.1%. Conclusion The technique of manipulative reduction on atlanto-axial subluxation acts more directly on the cause of the disease than the routine traction, and exerts better results in restoring proper atlanto-axiai joint position and mechanics stability of cervical vertebra.. Thus it is the effective shortcut way with high safety and low cost.