Study on Applicability of Microbiological Examination Methods for Shegan Mixture in Chinese Pharmacopoeia 2015 / 中国中医药信息杂志

Objective To standardize the method of microbiological examination on Shegan Mixture in Chinese Pharmacopoeia 2015. Methods Chinese Pharmacopoeia 2015 was used. Microbial enumeration test and specified microorganisms test were used to verify Shegan Mixture. The samples were treated by membrane filtration. Six kinds of strains for microbiological counting and limiting bacteria were used to study applicability. Results Microbial counts of the five strains of the recovery ratio were between 0.5 to 2, and Escherichia coli tested by control bacteria was qualified. Conclusion The microbiological examination methods for Shegan Mixture can meet the requirements of Chinese Pharmacopoeia 2015.