The Analgesic Effects Of Ginger-Juice (Zingiber Officinale Roscoe) On Wistar Albino Rat.

Background: In the view of contradictory reporting concerning analgesic effect, it was planned to investigate the analgesic effect of ginger-juice (ZINGIBER OFFICINALE ROSCOE) on wistar albino rat. Methodology: Wistar albino rats (n=6-12) were administered ginger juice (GJ) at doses (4ml/rat, p.o) as single administration (single dose) and repeated dose over a period of 7 days. Effect of treatment with G.J single and repeated (7days) dose was assessed. Parameter used during assessment was licking of paw after placing the rate on analgesiometer heated up to 50C. Results: The single and repeated administration of GJ (4ml/rat,p.o for 7 days) did not indicate analgesic effect on hot plate model. Conclusion: administered itself did not show analgesic effect on hot plate model.

Effect of shortening article publication time on medical journals / 中华医学图书情报杂志

The effect of shortening article publication time on the publication cycle, impact factor, contributions, quality control and sustainable development of medical journals was elaborated with some measures proposed for preventing their negative effect.

The Status of the Korea Blood Inventory Monitoring System, 2009~2012 / 대한수혈학회지

BACKGROUND: In the Republic of Korea, due to the low birth rate, blood donation is expected to decrease. However, the demand for blood is increasing as the proportion of elderly has increased. Korea Centers for Disease Control and Prevention operate the Korea Blood Inventory Monitoring System (KBIMs) for detection and response to the shortage of blood. The aim of this study was to show the trend of blood supply monitored by KBIMs. METHODS: This study analyzed the red blood cell inventory ratio, average daily usage, time-lag from blood donation to transfusion and from receipt to transfusion in blood banks monitored by KBIMs from 2009 to 2012. RESULTS: A total of 25 hospitals have participated in KBIMs since 2009. The average inventory ratio of blood banks was 5.3 days. By month, the inventory ratio was highest between November and February; and by week, highest on Fridays. Daily amount of RBC utilized in hospitals peaked on Thursday by week. Time-lag from blood donation to transfusion and from receipt to transfusion in blood banks was 12.2 and 6.4 days, respectively. The inventory ratio of type-A RBC was the lowest, because of the highest level of demand. In addition, time-lags from blood donation to transfusion and from receipt to transfusion were shortest in type-A RBC. CONCLUSION: The inventory ratio in blood banks monitored by KBIMs was stable throughout the years. However, due to higher level of demand, there is a risk of shortage of type-A RBC.

Time-lag from Submission to Printing in Indian Biomedical Journals.

The timeliness of publication in five Indian, clinical, biomedical journals (Indian Pediatrics, The Indian Journal of Pediatrics, Neurology India, The Indian Journal of Medical Research and Journal of Postgraduate Medicine) from January 2007 to December 2008 was compared. The time from manuscript submission to publication for the journals studied (median: 358.3 days; range: 202.9-421.3 days) was not significantly different.

Coating technique of pH-time lag colon-specific matrine delivery mini-pill / 中成药

AIM:To study the coating technique of pH-time lap colon-specific matrine delivery mini-pill consisted of the time lag release coating (inner layer) and enteric coating (out layer). METHODS:To filter the coating composition based on the index of dissolution of matrine and oxymatrine in vitro and the appearance rating of miui-pill. RESULTS:4 The coating composition of inner layer was the alcoholic solution,consisted of 2% EC,0.4% DEP and 2% talc powder. Then the coating composition of out layer was the alcoholic solution consisted of 5% Eudragit S100,3% talc powder and 0.5% TEC. The dissolution tests in vitro indicated that matrine and oxymatrine were not dissolved in the simulated gastric juice in 2 h. The accumulative amount of matrine and oxymatrine were less than 15% in the simulated intestinal fluid in 4 h. The amount of matrine and oxymatrine were 80.7% and 83.5% in the simulated colon juice in 2 h. CONCLUSION:The mini-pill could achieve the goal of delivering in the specific colon.