Application of Magnetization-prepared True Fast Imaging with Steady-state Precession Sequence in Brain Tumor Enhancement / 中国医学科学院学报

Objective To evaluate the application of two-dimensional magnetization-prepared true fast imaging with steady-state precession(2D-MP-TrueFISP)sequence in brain tumor enhancement.Methods In this study,60 cases of brain tumor patients who underwent enhanced magnetic resonance imaging of brain were scanned with 2D-MP-TrueFISP/two-dimensional spoiled gradient-recalled echo(2D-SPGR)before and after enhancement.The scores of lesions on the images of 2D-MP-TrueFISP/2D-SPGR were compared.At the same level of 2D-SPGE and 2D-MP-TrueFISP,the signal intensities(SIs)of lesions,white matter,and cerebrospinal fluid were measured before and after enhancement,and the contrast ratios(CRs)of lesions were calculated.The CRs before and after 2D-SPGR/2D-MP-TrueFISP enhancement and those between 2D-SPGR and 2D-MP-TrueFISP after enhancement were compared.Results The scores of lesions after 2D-MP-TrueFISP/2D-SPGR T1WI enhancement were 9.0(9.0,9.0)and 7.0(6.0,7.0),respectively,with significant difference(

Application of three-dimensional true fast imaging with steady-state precession sequence combined with diffusion tensor tractography for lumbar disc herniation / 中国介入影像与治疗学

Objective: To explore the value of three-dimensional true fast imaging with steady-state precession (3D-Ture FISP) sequence combined with diffusion tensor tractography (DTT) in determining the responsible nerve root of sciatica caused by lumbar disc herniation (LDH). Methods: MR examinations of lumbosacral region were performed on 40 LDH patients with unilateral sciatica (lesion group) and 40 healthy volunteers (control group). FA and ADC values of bilateral nerve roots were measured at L4-S1 vertebral level based on 3D-Ture FISP sequence and DTT fusing images. The responsible nerve roots of LDH patients with sciatica were detected combining with morphologic findings, course and FA and ADC values of the nerve roots shown on the fusing images. And statistical analysis was carried out. Results: All 3D-True FISP sequence and DTT fusing images could clearly show the morphology and course of nerve roots. In lesion group (51 involved nerve roots and 189 uninvolved nerve roots), 37 cases were found to be in accordance with the clinical symptoms whereas 3 cases were not. In control group (240 nerve roots), there was no statistical difference of FA and ADC values between the left and the right nerve roots (both P>0.05). The mean FA value of bilateral nerve roots was 0.346±0.042, and the mean ADC value was (1.296±0.080)mm2/s. The mean FA and ADC values of involved nerve roots in lesion group was 0.253±0.021 and (1.743±0.089)mm2/s, respectively. And the mean FA and ADC values of contralateral uninvolved nerve roots was 0.339±0.013 and (1.297±0.075)mm2/s, respectively. FA value of involved nerve roots in lesion group was significantly lower than that of contralateral uninvolved nerve roots in lesion group (t=0.806, P=0.038) and the mean FA value of control group (t=0.963, P=0.043), respectively,while ADC value significantly increased compared with contralateral uninvolved nerve roots (t=0.866, P=0.040) and control group (t=0.921, P=0.042). There was no statistical difference of the mean FA and ADC values between contralateral nerve roots in lesion group and control group (both P>0.05). Conclusion: 3D-Ture FLSP sequence combined with DTT technique can not only clearly show the anatomical morphology and course of nerve root, but also quantitatively detect the responsible nerve roots of sciatica in LDH patients, so as to provide information for clinical diagnosis and treatment.

MR findings and comparative study of MR sequences in several twin pregnancy with comorbidities / 实用放射学杂志

Objective To compare the applications of half-Fourier acquisition single-shot turbo spin-echo(HASTE)sequence and true fast imaging with steady state precession(True FISP)sequence for the delineation of structures and diseases in several twin pregnancy with comorbidities and to explore the clinical value of two series of fast imaging for MRI of fetus.Methods 27 twin preg-nancy women with comorbidities were imaged with HASTE and True FISP sequences.All images were statistically analyzed in re-spect of imaging qualities and artifacts.MR signs of fetal brain were analysized.Results There were abnormal changes in brains in 7 of 27 cases.Both sequences could demonstrate the structures and lesions of the fatus.Imaging quality scores of HASTE were higher than that of True FISP,but with more respiratory blurring.Conclusion There might be varying abnormalities in central nervous system in twin pregnancy with comorbidities.Combining the demonstration abilities of HASTE and True FISP is needed when de-tecting fetus lesions,especially the brain.