RESUMEN
To evaluate different features of pyogenic liver abscess. Prospective descriptive study. This study was conducted in the Medical Department of Al Tibri Medical College and Hospital, Karachi from Jan 2011 to Jan 2013. Patient presented with upper abdominal pain and fever of more than two weeks duration. All patients undergone ultrasound of abdomen reported at Al Tibri Medical College and hospital were enrolled in the study. All data was recorded in a preset proforma and features like biodata, symptoms, sign, biochemical test, ultrasonographic finding, culture and sensitivity of pus were assessed. The data were analyzed on SPSS version 15. Total cases were 67. Male were 47 and female were 20. The mean age was 47 +/- 18. With range from 29 to 65 years. Male were more as compared with females. The commonest symptoms were abdominal pain in 43 cases [64%], fever was in 39 cases [58%], anorexia was in 39 cases [58%], Jaundice was in 29 cases [43%], weight loss in 24 cases [37%], raised ESR was in 42 cases [62%], raised leukocyte count was in 57 cases [86%], raised bilirubin in 46 cases [69%] ALT was raised in 27cases [40%] and alkaline phosphatase was raised in 20 cases [29%], ultrasound abdomen showing single abscess in 55 cases [83%] and multiple in 12 cases [17%], right lobe involvement in 53 cases [79%], left lobe involvement in 14 cases [21%], 37 cases [55%] were under gone therapeutic percutaneous ultrasound guided aspiration of the abscess . Culture were positive in 49 cases [73%], in which Klebsella pneumonia was the commonest organism found in 22 cases [45%], Enterococcus supp were in 11 cases [23%], E-coli were in 9 cases [18%], While the culture is negative in 18 cases [27%]. No mortality were recorded. The pyogenic liver abscess is one of the common cause of upper abdominal pain and fever of longer duration