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1.
Arq. Inst. Biol. (Online) ; 77(2): 301-308, abr.-jun. 2010. tab, graf
Artículo en Portugués | VETINDEX, LILACS | ID: biblio-1390861

RESUMEN

Das sementes da mamona extrai-se o óleo de rícino, utilizado in natura ou em sua forma modificada nas áreas médica, farmacêutica e industrial. Um de seus derivados químicos - o Poliquilgerm® - evidencia propriedades antifúngicas sobre Candida albicans e bacteriostática/ bactericida sobre Escherichia coli no nível de 99,9%. Considerando-se essas propriedades, aplicouse o Poliquilgerm® em culturas de Leuconostoc mesenteroides, uma das espécies de bactéria contaminante dos mostos em indústrias sucroalcooleiras. Esta bactéria quando presente em mostos produz além do ácido láctico, a dextrana, que é um polímero da glicose que aumenta a viscosidade dos fluidos dos processos. No presente trabalho avaliou-se o efeito de diferentes concentrações do Poliquilgerm® sobre a viscosidade produzida por L. mesenteroides em diferentes meios de cultivo, condições de pH, e temperatura. Verificou-se 20,56% de diminuição da viscosidade quando se utilizou 1,0% do produto, além da inibição do crescimento da bactéria após 20 horas em contato com 1,0 e 0,2% de Poliquilgerm®. L. mesenteroides apresentou melhor crescimento em valores de pH 6,0, tanto a 28 como a 33º C, evidenciado pela maior produção de biomassa. Além disso, em meio de cultura neste pH verificou-se maior porcentagem de diminuição da viscosidade em ambas as concentrações utilizadas. Estas mesmas concentrações alcançaram até 100% de diminuição das UFC/mL após 24 horas em contato com o produto, evidenciado por quantificação da biomassa e confirmado mediante plaqueamento pela técnica "Pour Plate".


Castor-oil, extracted from seeds of Ricinus communis L., is normally used in natura or in its modified form in the medical, pharmaceutical and industrial areas. One of its chemical derivates ­ Poliquilgerm® ­ has shown antifungal properties on Candida albicans, and bacteriostatic/bactericide effects on Escherichia coli reaching 99.9%. Considering these features, in the present study Poliquilgerm® was applied in cultures of Leuconostoc mesenteroides, a frequent contaminant bacterium of musts in the sugar and alcohol industries. This bacterium, when a contaminant of must, produces lactic acid as well as dextran, a polymer of glucose which may increase the viscosity of fluids in the operation. The present study evaluated the effect of different concentrations of Poliquilgerm® on viscosity produced by L. mesenteroides cultures under different conditions of various culture media, pH and temperature. A 20.56% decrease in viscosity was verified when 1.0% of the product was used, and bacterium growth inhibition after 20 hours in media with 1.0 and 0.2% of Poliquilgerm®. L. mesenteroides showed a higher growth rate in pH 6.0, at both 28 and 33º C, evidenced by greater biomass production. Also, in the culture media at this pH a greater decrease in viscosity percentages was verified at both concentrations used. The media with these same concentrations reached up to 100% decrease of UFC/mL after 24 hours in the presence of the product, observed by biomass quantification and confirmed by the Pour Plate technique.


Asunto(s)
Viscosidad , Aceite de Ricino/administración & dosificación , Leuconostoc mesenteroides , Residuos Industriales/análisis , Antifúngicos/administración & dosificación , Ricinus communis , Industria del Alcohol , Industria del Azúcar
2.
Artículo en Inglés | IMSEAR | ID: sea-38870

RESUMEN

OBJECTIVE: To compare castor oil and sodium phosphate preparation (Swiff) in patients' satisfaction, efficacy for colon cleanness, side effects, and prices. MATERIAL AND METHOD: One hundred patients referred for barium enema were randomized to receive castor oil (n = 50) and sodium phosphate preparation (n = 50). They graded their satisfaction using a 5-point scale (easy, acceptable, slightly difficult, extremely difficult, and unacceptable). The efficacy for colon cleanness was graded by two radiologists using a 5-point scale (excellent, easy for evaluation, acceptable, difficult for evaluation, and unacceptable). Side effects were evaluated by patients' vital signs, total number of bowel frequency, and 10 associated symptoms. RESULTS: Both preparations revealed no difference in patients' satisfaction (p = 0.882) and efficacy of colon cleanness (p = 0.130). Sodium phosphate preparation was more expensive (79 vs. 10 Baht) and caused higher number of bowel frequency (p < 0.001). CONCLUSION: With a cheaper price, castor oil was comparable with sodium phosphate preparation in patients' satisfaction and efficacy of colon cleanness.


Asunto(s)
Adulto , Anciano , Anciano de 80 o más Años , Aceite de Ricino/administración & dosificación , Catárticos/administración & dosificación , Colon/diagnóstico por imagen , Enema , Femenino , Humanos , Masculino , Persona de Mediana Edad , Satisfacción del Paciente , Fosfatos/administración & dosificación , Método Simple Ciego , Adulto Joven
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