Adenocarcinoma sincrónico de alto grado de endometrio y ovario; a propósito de un caso clínico / Synchronous high-grade adenocarcinoma of the endometrium and ovary; about a clinical case

RESUMEN El cáncer sincrónico endometrial y ovárico (SEOC) representa alrededor de un 5-10% de las neoplasias de endometrio y ovario. Cuando no existe extensión locorregional y presentan un patrón histológico de bajo grado, actúan como si fueran dos tumores primarios independientes, en lugar de comportarse como un cáncer en estadio avanzado. Los mecanismos para diferenciar si su origen es metastásico o por el contrario, son tumores primarios independientes conlleva una gran dificultad y ha generado una importante controversia dentro del estudio de este tipo de neoplasias. En este artículo, exponemos el caso clínico de una paciente de 46 años que presenta un tumor sincrónico de endometrio y ovario en estadio IA, desconocido hasta el estudio histológico de la pieza quirúrgica.

ABSTRACT Endometrial and ovarian synchronous cancer (SEOC) accounts for about 5-10% of endometrial and ovarian neoplasms. When there is no local extension and they present a low-grade histological pattern, they act as if they were two independent primary tumours, instead of behaving as an advanced stage cancer. Therefore, the differentiation of its origin (metastatic or independent primary tumours) is fraught with difficulty and has generated a significant controversy in the study of this type of neoplasms. In this article, we present the clinical case of a 46-year-old patient presenting a synchronous tumor of the endometrium and ovary in IA stage, unknown until the histological study of the surgical sample.

Synchronous Malignant Intraductal Papillary Mucinous Neoplasms of the Bile Duct and Pancreas Requiring Left Hepatectomy and Total Pancreatectomy / 대한소화기학회지

Intraductal papillary mucinous neoplasm of the bile duct (IPMN-B) and intraductal papillary mucinous neoplasm of the pancreas (IPMN-P) have striking similarities and are recognized as counterparts. However, simultaneous occurrence of IPMN-B and IPMN-P is extremely rare. A 66 year-old female presented with recurrent epigastric pain and fever. During the past 9 years, she had three clinical episodes related to intrahepatic duct stones and IPMN-P in the pancreas head and was managed by medical treatment. Laboratory test results at admission revealed leukocytosis (12,600/mm3) and elevated CA 19-9 level (1,200 U/mL). Imaging study demonstrated liver abscess in the Couinaud's segment 4, IPMN-B in the left lobe, and IPMN-P in the whole pancreas with suspicious malignant change. Liver abscess was drained preoperatively, followed by left lobectomy with bile duct resection and total pancreatectomy with splenectomy. On histologic examination, non-invasive intraductal papillary mucinous carcinoma arising from various degree of dysplastic mucosa of the liver and pancreas could be observed. However, there was no continuity between the hepatic and pancreatic lesions. This finding in our case supports the theory that double primary lesions are more likely explained by a diffuse IPMN leading to synchronous tumors arising from both biliary and pancreatic ducts rather than by a metastatic process. Herein we present a case of simultaneous IPMN of the bile duct and pancreas which was successfully treated by surgical management.

Fallopian tube carcinoma.

Primary adenocarcinoma of Fallopian tube is a rare gynecological malignancy affecting women in the fifth and sixth decades of their lives. The rarity of this type of carcinoma has prompted reports of individual cases rather than publication of a large series. One such case is reported in a 50-year-old nulliparous post-menopausal female. The age, low fertility index and presentation of the disease are in accordance with previous reports in the literature. The present case also fulfills the diagnostic criteria's applied to this tumor.

Ductal Adenocarcinoma Mimicking Intraductal Papillary Mucinous Neoplasm of the Pancreas / 대한소화기학회지

No abstract available.

Two Cases of Pancreatic Ductal Adenocarcinoma, Manifested as Solid Pseudopapillary Tumor and Intraductal Papillary Mucinous Neoplasm / 대한소화기학회지

Compared with other types of cancers, pancreatic cancer is one of the most dreadful malignancies and is fifth leading cause of cancer-related death in Korea. It is difficult to expect early diagnosis or improvement in prognosis due to lack of specific early symptoms and effective diagnostic methods. Whereas cystic neoplasm of the pancreas is a rare type of pancreatic tumor, surgical resection provides good prognosis because of its low possibility of local invasion or distant metastasis. In case of pancreatic cystic tumor, radiologic differentiation between benign and malignant lesions is crucial for the selection of appropriate treatment and the prediction of prognosis. And ductal adenocarcinoma of pancreas presenting in cystic form is an uncommon type of cystic tumor, making it extremely rare among all pancreatic malignancies. We report two cases of atypical pancreatic ductal adenocarcinoma presenting as solid pseudopapillary tumor and intraductal papillary mucinous neoplasm, respectively.

Paratesticular papillary serous cystadenocarcinoma--a case report.

A case of paratesticular papillary serous cystadenocarcinoma in a six year old child is presented. The occurrence of these epithelial tumours of the ovarian type, in the paratesticular region is extremely rare and only six cases have been reported so far. They are thought to arise from Mullerian metaplasia of the peritoneal lining of the tunica vaginalis, appendix testis or mullerian remnants between the testis and spermatic cord.

Carcinoma de parótida e mama concomitantes: relato de caso / Parotid carcinoma concomitant with breast carcinoma: case report

O risco de desenvolvimento de câncer de mama em pacientes que apresentam carcinoma de glândula salivar é discutido desde 1968. Entretanto, não foi encontrado um fator causal comum responsável por esta associação. Os autores relatam um caso de adenocarcinoma papilífero de parótida direita, em uma paciente de 85 anos que também apresentava sincronicamente um carcinoma ductal invasivo da mama ipsilateral à neoplasia da parótida. Clinicamente haviam dados para a malignidade em ambas as lesões. O diagnóstico foi confirmado por citologia da parótida e histologicamente por biópsia na mama. A proposta inicial foi de parotidectomia mais esvaziamento cervical unilateral modificado e mastectomia. A paciente recusou-se ao procedimento de mastectomia, apenas aceitou a proposta cirúrgica para a parótida. Foi realizado parotidectomia total mais esvaziamento cervical modificado, para avaliação radioterápica pós-operatória e uso de tamoxifen para a patologia mamária. Houve uma resposta satisfatória importante na neoplasia da mama, com conseqüente involução da mesma, mas houve recidiva do adenocarcinoma na região parotídea direita, um ano após a primeira cirurgia. Nesta ocasião, realizou-se a ressecção da recidiva com esvaziamento clássico e reconstrução com retalho delto peitoral porque havia comprometimento da pele. Atualmente, após o último procedimento, a paciente vem em controle ambulatorial sem sinais de recidiva local...

Caso inusual de cáncer de ovario avanzado / Unusual case of advanced ovarian cancer

El cáncer de ovario, es una patología de diagnóstico tardío y de alta mortalidad en sus estadios avanzados. Se presenta el caso de una paciente de 51 años, portadora de un cáncer de ovario (Cistoadenocarcinoma seroso papilar ovárico bilateral) estadio IIIb, con 13 años de sobrevida post tratamiento. Se analiza tanto su historia clínica, estudio, tratamiento y su evolución en el tiempo

Primary carcinoma of the fallopian tube: a 20-year review at Ramathibodi Hospital.

Four cases of primary carcinoma of the fallopian tube treated at the Department of Obstetrics and Gynaecology, Ramathibodi Hospital, Mahidol University during a 20-year period were reviewed. The mean age was 54 years. The most common presenting symptoms were watery vaginal discharge, abnormal uterine bleeding and abdominal pain. A palpable abdominal or pelvic mass was also a common physical finding. The preoperative diagnosis was correct in three patients. The possibility of getting an early and correct preoperative diagnosis of this disease is also discussed. All of the patients in this report were in stage I & II. The initial treatment consisted of total abdominal hysterectomy and bilateral salpingo-oophorectomy with postoperative radiotherapy or chemotherapy.

Carcinoma del conducto tirogloso / Thyroglossal duct carcinoma

Se presenta un caso de carcinoma del conducto tirogloso y se revisa la literatura. Este es un tumor inusual del cual pocas veces se sospecha en el preoperatorio. El examen microscópico es diagnóstico. Hasta la fecha, se han reportado 141 casos en la literatura, Desde el punto de vista histológico, el recubrimiento epitelial de los remanentes es variable, y tejido tiroideo se ha encontrado hasta en un 62% de los remanentes tiroglosos. La incidencia del carcinoma es mayor en la tercera década, y en mujeres 1,7:1. El tipo histopatológico más común es el edenocarcinoma papilar (79%). El origen primario del carcinoma tirogloso se confirma con esta. revisión. Hubo diferentes modalidades de tratamiento y no es posible determinar la mejor terapia, sin embargo, se hacen recomendaciones. La tasa de mortalidad es baja, y aparentemente sigue el mismo patrón de los carcinomas tiroideos