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Rev. méd. Chile ; 141(8): 1041-1048, ago. 2013. ilus, tab
Artículo en Español | LILACS | ID: lil-698703

RESUMEN

For years the mainstay of antiphospholipid syndrome treatment has been anticoagulation and antiplatelet therapy, but the autoimmune nature of the disease, and complications of these therapies, created the need to develop new therapeutic strategies. New therapeutic alternatives inhibit at different levels, the cascade of events leading to the pro-thrombotic state characteristic of the antiphospholipid syndrome. We conducted a literature review of these new treatments, focusing on the pathophysiological bases that support them and their possible clinical applications.


Asunto(s)
Humanos , Síndrome Antifosfolípido/tratamiento farmacológico , Agmatina/análogos & derivados , Agmatina/uso terapéutico , Anticuerpos Monoclonales de Origen Murino/uso terapéutico , Síndrome Antifosfolípido/fisiopatología , Dipéptidos/uso terapéutico , Glucocorticoides/uso terapéutico , Hidroxicloroquina/uso terapéutico , Inhibidores de Hidroximetilglutaril-CoA Reductasas/uso terapéutico , Trombosis/tratamiento farmacológico
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