1.
Indian J Physiol Pharmacol
;
1975 Jan-Mar; 19(1): 34-8
Artículo
en Inglés
| IMSEAR
| ID: sea-108466
RESUMEN
Two basic anilides EA-7 and EA-8 were investigated for their antispasmodic activity against a variety of spasmogens on different tissues from different species of animals and comparison was made with lignocaine. EA-8 was found to be the most potent in this respect, followed by EA-7 and lignocaine. The antispasmodic potency does not correspond to their local anaesthetic potency. This suggests a direct depressant effect on tissues.
Asunto(s)
Acetilcolina/antagonistas & inhibidores , Anestésicos Locales/farmacología , Anilidas/farmacología , Animales , Aorta/efectos de los fármacos , Bario/antagonistas & inhibidores , Depresión Química , Epinefrina/antagonistas & inhibidores , Cobayas , Antagonistas de los Receptores Histamínicos H1 , Íleon/efectos de los fármacos , Lidocaína/farmacología , Contracción Muscular/efectos de los fármacos , Músculo Liso/efectos de los fármacos , Norepinefrina/antagonistas & inhibidores , Conejos , Ratas , Tráquea/efectos de los fármacos
2.
Indian J Physiol Pharmacol
;
1974 Apr-Jun; 18(2): 97-101
Artículo
en Inglés
| IMSEAR
| ID: sea-108099