Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 2 de 2
Filtrar
Añadir filtros








Intervalo de año
1.
Journal of Korean Medical Science ; : S41-S45, 2010.
Artículo en Inglés | WPRIM | ID: wpr-61694

RESUMEN

The purpose of this study was to review occupational reproductive abnormalities and occupational bladder cancer in Korea and to discuss their toxicological implications. Reproductive dysfunction as a result of 2-bromopropane poisoning was first reported in Korean workers. In 1995, 23 of the 33 workers (25 female and 8 male workers) who were exposed to 2-bromopropane during the assembly of tactile switch parts developed reproductive and/or hematopoietic disorders. A total of 17 (68%) workers were diagnosed with ovarian failure. Two of the eight male workers experienced azoospermia and four workers experienced some degree of oligospermia or reduced sperm motility. In summary, 2-bromopropane poisoning caused severe reproductive effects in Korean workers. The prognosis was poor for reproductive dysfunction. A few cases of occupational bladder cancer have been reported in Korea, whereas other cancers of the urinary tract have not been reported after occupational exposure. A few cases of benzidine-induced cancer have been reported in Korea and 592 workers in Japan have received compensation for benzidine and beta-naphthylamine-induced cancer. In conclusion, a few cases of benzidine-induced occupational bladder cancer have been reported in Korea. However, benzidine-induced bladder cancer will likely be an important occupational health issue in Korea in the coming years.


Asunto(s)
Femenino , Humanos , Masculino , 2-Naftilamina/toxicidad , Azoospermia/inducido químicamente , Bencidinas/toxicidad , Hidrocarburos Bromados/toxicidad , Infertilidad/inducido químicamente , Enfermedades Profesionales/inducido químicamente , Exposición Profesional/efectos adversos , Oligospermia/inducido químicamente , Insuficiencia Ovárica Primaria/inducido químicamente , República de Corea , Motilidad Espermática/efectos de los fármacos , Neoplasias de la Vejiga Urinaria/inducido químicamente
2.
Indian J Exp Biol ; 1993 Mar; 31(3): 299-300
Artículo en Inglés | IMSEAR | ID: sea-60678

RESUMEN

Susceptibility of carcinogen (benzidine hydrochloride) was checked by degranulation technique in rats of three different (young, adult and old) age groups. The dose response curves of these three different groups showed different per cent degranulation. Comparative data of dose response of benzidine hydrochloride observed on the basis of RNA/Protein ratio basis showed that old animals were more susceptible to carcinogens than young and adult animals.


Asunto(s)
Envejecimiento , Animales , Bencidinas/toxicidad , Carcinógenos/toxicidad , Degranulación de la Célula/efectos de los fármacos , Masculino , Microsomas Hepáticos/efectos de los fármacos , Ratas
SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA