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Artículo en Inglés | IMSEAR | ID: sea-91279

RESUMEN

Nifedipine was evaluated in the prophylaxis of 28 patients each of migraine and tension headache using a double blind cross over design with random allocation to drug or placebo group. The duration of the trial was 3 months with a 2 week run-in period and 2 week wash-oat period separating two treatment periods of 4 weeks each. A satisfactory response was obtained in 71.4% of migraineurs (p < 0.001) and 28.6% of patients with tension headache (p = N.S). Minor side effects were observed in 5 patients. Nifedipine is a useful agent for the management of migraine as it reduces frequency and severity of pain but the drug cannot be recommended for tension headache.


Asunto(s)
Adulto , Bloqueadores de los Canales de Calcio/efectos adversos , Estudios Cruzados , Método Doble Ciego , Esquema de Medicación , Femenino , Humanos , Masculino , Trastornos Migrañosos/prevención & control , Nifedipino/efectos adversos , Cefalea de Tipo Tensional/prevención & control , Factores de Tiempo
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