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1.
Hist. ciênc. saúde-Manguinhos ; 26(1): 245-264, Jan.-Mar. 2019.
Artículo en Inglés | LILACS | ID: biblio-989863

RESUMEN

Abstract This paper focuses on geneticists Salvador Armendares's and Rubén Lisker's studies from the 1960s to the 1980s, to explore how their work fits into the post-1945 human biological studies, and also how the populations they studied, child and indigenous, can be considered laboratories of knowledge production. This paper describes how populations were considered for different purposes: scientific inquiry, standardization of medical practices, and production or application of medicines. Through the narrative of the different trajectories and collaborations between Armendares and Lisker, this paper also attempts to show the contact of their scientific practices, which brought cytogenetics and population genetics together at the local and global levels from a transnational perspective.


Resumo Aborda o trabalho dos geneticistas Salvador Armendares e Rubén Lisker, entre 1960 e 1980, para analisar como se insere nos estudos biológicos humanos do pós-1945, e demonstra como as populações estudadas por eles, a infantil e a indígena, podem ser consideradas laboratórios de produção de conhecimento. O artigo revela como as populações foram consideradas para diversos propósitos: investigação científica, padronização das práticas médicas e produção ou aplicação de suas medicinas. Por meio da narrativa das diferentes trajetórias e colaborações entre Armendares e Lisker, também procura discutir o contato de suas práticas científicas, que colocaram a citogenética e a genética de populações lado a lado nos níveis local e global a partir de uma perspectiva transnacional.


Asunto(s)
Humanos , Niño , Historia del Siglo XX , Genética Humana/historia , Pueblos Indígenas/historia , Genética de Población/historia , Errores Innatos del Metabolismo de los Carbohidratos/historia , Citogenética/historia , Lactasa/deficiencia , Lactasa/historia , Pueblos Indígenas/genética , Deficiencia de Glucosafosfato Deshidrogenasa/historia , Cariotipificación/historia , México
5.
Rev. biol. trop ; 52(3): 537-544, sept. 2004.
Artículo en Español | LILACS | ID: lil-501727

RESUMEN

This is an overview of the past, present and future of human Cytogenetics in Costa Rica. It started in 1965 at the University of Costa Rica where it has been developed slowly but steadily. There is only one overloaded clinical cytogenetic laboratory in the social security system. The tests currently performed are peripheral blood and blood marrow karyotypes, prenatal cytogenetic diagnosis (amniotic fluid and fetal blood) and less frequently skin biopsies. The task now is to standardize molecular cytogenetic techniques, we are actually working with PRINS in order to study submicroscopic subtelomeric rearrangements associated with mental retardation and other microdeletion syndromes as well.


Asunto(s)
Humanos , Recién Nacido , Niño , Adolescente , Adulto , Historia del Siglo XX , Historia del Siglo XXI , Citogenética/historia , Citogenética/tendencias , Técnicas de Diagnóstico Molecular/historia , Técnicas de Diagnóstico Molecular/tendencias , Citogenética/métodos , Costa Rica , Técnicas de Diagnóstico Molecular/métodos
6.
Rev. méd. Chile ; 131(2): 220-224, 2003.
Artículo en Español | LILACS | ID: lil-342246

RESUMEN

The classical Mendelian genetics forged the development of biomedical sciences in the twentieth century. However, the classical works that allowed the sequencing of human genoma, have not received the recognition that they deserve. The author does a historical revision of works, considered classic in genetics and its specialties such as cytogenetics, biochemical genetics, immunogenetics and molecular genetics, published between 1990 and 1999. Authors that received the Nobel Prize are identified and the works are sorted in chronological order. Most founders of genetics specialties, have not received the Nobel Prize. Only 26 of 80 classical works have been awarded with such distinction. Almost all founders of Mendelian genetics and human cytogenetics, have been unrewarded. The author proposes to create the "Johan Gregory Mendel Prize" for geneticists


Asunto(s)
Humanos , Genética/historia , Historia de la Medicina , Genoma Humano , Biología Molecular/historia , Citogenética/historia , Inmunogenética/historia , Selección de Libros
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