Acute acalculous perforated cholecystitis

A case of acute acalculous perforated cholecystitis with acute generalized peritonitis in a middle aged cachectic man, presenting late in a moribund condition, is reported. He underwent emergency laparotomy [subtotal cholecystectomy], went into multi-organ failure and was managed accordingly. The patient recovered in about 2 weeks and was followed-up regularly

Acute acalculous cholecystitis in an immunocompetent patient with severe acquired toxoplasmosis

Acute acalculous cholecystitis (AAC) is an inflammatory disease of the gallbladder not associated with gallstones. It is more often seen in hospitalized patients on mechanical ventilation due to life-threatening conditions and superimposed sepsis. Occasionally, infection itself may be the only predisposing factor identified. AAC has rarely been observed in severely immunocompromised patients with reactivated Toxoplasma infection. We were able to document for the first time a case of AAC in an otherwise healthy adult with acute acquired toxoplasmosis. A prompt diagnosis and early onset of effective antiparasitic treatment allowed the resolution of the episode without further complication